Protein Alignment Atf3 and Fos

DIOPT Version :10

• Sequence 1: NP_001259125.1
• Gene: Atf3 / 43867
• FlyBaseID: FBgn0028550
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_034364.1
• Gene: Fos / 14281
• MGIID: 95574
• Length: 380
• Species: Mus musculus
• Alignment Length: 488
• Identity: 114/488 - (23%)
• Similarity: 184/488 - (37%)
• Gaps: 158/488 - (32%)

  Fly    61 SSSASCSAASTPVVTVRHFNGHPNGQS----HSQDSSHSSCSGSPLDS---------------PA 106
            :||:.||:||            |.|.|    ||...|.|| .|||:::               |.
Mouse    12 ASSSRCSSAS------------PAGDSLSYYHSPADSFSS-MGSPVNTQDFCADLSVSSANFIPT 63

  Fly   107 GTA--TTPSVQQTCSRLIKEGLKLSIQSKRKLSTCDSSSGSEQPHSKYS--RRSSNHNGHSGSSN 167
            .||  |:|.:|.    |::..|..|:          :.|.:..|| .|.  .:|:.....:|...
Mouse    64 VTAISTSPDLQW----LVQPTLVSSV----------APSQTRAPH-PYGLPTQSAGAYARAGMVK 113

  Fly   168 NYSGSMSNANDLDDDCEESSDDDSETKSQPKGLTPEDEDRRRRRRERNKIAATKCRMKKRERTQN 232
            ..||..:.:.......|:              |:||:|::||.||||||:||.|||.::||.|..
Mouse   114 TVSGGRAQSIGRRGKVEQ--------------LSPEEEEKRRIRRERNKMAAAKCRNRRRELTDT 164

  Fly   233 LIKESEVLDTQNVELKNQVRQLETERQKLVDMLKSHGCQRAGGCQLPSQLLQSPAQKYLSELELE 297
            |..|::.|:.:...|:.::..|..|::||..:|.:|    ...|::|..|      .:..|:.:.
Mouse   165 LQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAH----RPACKIPDDL------GFPEEMSVA 219

  Fly   298 TVSIDGPNSGNNNQRLQSIPSMATFKYGSKTAAAMAQQLPNGYCKPSPSAQEFEHAGYQQQQQQQ 362
            ::.:.|           .:|..:|    .::..|....|.|. .:|.||.:..:..     ...:
Mouse   220 SLDLTG-----------GLPEAST----PESEEAFTLPLLND-PEPKPSLEPVKSI-----SNVE 263

  Fly   363 QQQQP--QSLNPAGNNVIDQQHANPSPSLLSDYVPNCDGLTGS---ASNHPSHNNNNNNNNSSGA 422
            .:.:|  ..|.||.        :.||.|..|..||:.| |:||   |...|.|      :||.|.
Mouse   264 LKAEPFDDFLFPAS--------SRPSGSETSRSVPDVD-LSGSFYAADWEPLH------SNSLGM 313

  Fly   423 SSNTSNNNSNISSHSSNATSSTTPTATSSAIEFVKNELVDSQSPYTTALSAERFLFEPSDGFPDI 487
            .                      |..|.  :|.:...:|......||..|:..|.:..:|.||
Mouse   314 G----------------------PMVTE--LEPLCTPVVTCTPGCTTYTSSFVFTYPEADSFP-- 352

  Fly   488 KHACVLPSPCGINGLNMASVVNTNGSTGNNNNS 520
              :|              :..:..||:.|..:|
Mouse   353 --SC--------------AAAHRKGSSSNEPSS 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf3	NP_001259125.1	bZIP_ATF3	215..268	CDD:269870	19/52 (37%)
		coiled coil	215..265	CDD:269870	18/49 (37%)
Fos	NP_034364.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	117..141		6/37 (16%)
		Basic motif, required for the activation of phospholipid synthesis, but not for CDS1-binding	139..159		13/19 (68%)
		bZIP_Fos	147..200	CDD:269869	19/52 (37%)
		coiled coil	147..199	CDD:269869	19/51 (37%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	165..193		6/27 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	354..380		5/30 (17%)