Protein Alignment Atf3 and ATF7-NPFF

DIOPT Version :10

• Sequence 1: NP_001259125.1
• Gene: Atf3 / 43867
• FlyBaseID: FBgn0028550
• Length: 688
• Species: Drosophila melanogaster
• Sequence 2: NP_001353488.1
• Gene: ATF7-NPFF / 114108587
• HGNCID: 55073
• Length: 463
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 77/334 - (23%)
• Similarity: 122/334 - (36%)
• Gaps: 100/334 - (29%)

  Fly     7 PASSLLSIDSGGLLMGGHTPKTPEILNSLIAMTNPLENFSYSSAAAAAAAVSVASSSASCSAAST 71
            |.|.:.........||..|...|.:::.....|.|:   .........:.:|:|          .
Human   172 PTSVITQAPPSNRQMGSPTGSLPLVMHLANGQTMPV---LPGPPVQMPSVISLA----------R 223

  Fly    72 PVVTVRHFNGHPNGQSHSQDSSHSSCSGSPLDSPAGTATTPSVQQTCSRLIKEGLKLSIQSKRKL 136
            ||..|.:..|.|....:|  |...|.||.|:.|.|                |..||.::
Human   224 PVSMVPNIPGIPGPPVNS--SGSISPSGHPIPSEA----------------KMRLKATL------ 264

  Fly   137 STCDSSSGSEQPHSKYSRRSSNHNGHSGSSNNYSGSMSNANDLDDDCEES----SDDDSETKSQP 197
                            :.:.|:.||..|.....:.:|..|..     |:|    ...|:.:.:||
Human   265 ----------------THQVSSINGGCGMVVGTASTMVTARP-----EQSQILIQHPDAPSPAQP 308

  Fly   198 KGLTP----------------EDEDRRRRR-RERNKIAATKCRMKKRERTQNLIKESEVLDTQNV 245
            : ::|                ||.|.||:| .|||:.||::||.|::....:|.|::|.|.:||:
Human   309 Q-VSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNI 372

  Fly   246 ELKNQVRQLETERQKLVDMLKSH-GCQRAGGCQLPSQLLQSPAQKYLSELELE-----------T 298
            :|.|:|..|..|..:|..:|.:| .|        |...||...|.||...:..           |
Human   373 QLSNEVTLLRNEVAQLKQLLLAHKDC--------PVTALQKKTQGYLGGRQRTPPTTGCPDLWVT 429

  Fly   299 VSIDGPNSG 307
            |::..|.:|
Human   430 VALPAPGNG 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf3	NP_001259125.1	bZIP_ATF3	215..268	CDD:269870	19/52 (37%)
		coiled coil	215..265	CDD:269870	18/49 (37%)
ATF7-NPFF	NP_001353488.1	C2H2 Zn finger	9..31	CDD:275370
		GCN4_cent	47..84	CDD:213399
		bZIP_ATF2	334..394	CDD:269835	24/59 (41%)
		coiled coil	334..394	CDD:269835	24/59 (41%)