Protein Alignment HnRNP-K and PBP2

DIOPT Version :10

• Sequence 1: NP_995906.1
• Gene: HnRNP-K / 43862
• FlyBaseID: FBgn0267791
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_009792.3
• Gene: PBP2 / 852533
• SGDID: S000000437
• Length: 413
• Species: Saccharomyces cerevisiae
• Alignment Length: 529
• Identity: 98/529 - (18%)
• Similarity: 177/529 - (33%)
• Gaps: 189/529 - (35%)

  Fly     3 KRLRMKREMNDEGEGPQDQKRNRRNEETVRILIPSSIAGAVIGKGGQHIQKMRTQYKATVSVDDS 67
            ||:.:| :.:...:...|...|..::..:|:|.....|..::|..|..|.:::::..|.:::.::
Yeast    42 KRVALK-DADSHSDNDHDSPDNVPSDVHLRMLCLVKHASLIVGHKGATISRIKSETSARINISNN 105

  Fly    68 -QG-PERTIQISADIESTLE----IITEMLKYF--EERDEDFD--VRLLIHQSLAGCVIGKGGQK 122
             :| |||.:.:....:...:    |:..:|:..  |:..||.:  :.|||...|.||:|||.|.:
Yeast   106 IRGVPERIVYVRGTCDDVAKAYGMIVRALLEEHGNEDNGEDIEISINLLIPHHLMGCIIGKRGSR 170

  Fly   123 IKEIRDRIGCRFLKVFS--NVAPQSTDRVVQTVGKQSQVIEAV----REVITLTRDTP---IKGA 178
            ::||.|....   |:|:  |....|.||::...|....:..|.    :.::....::|   :|.:
Yeast   171 LREIEDLSAA---KLFASPNQLLLSNDRILTINGVPDAIHIATFYISQTLLNFQMESPQKNVKRS 232

  Fly   179 IHNYDPMNFDRVYADEYGGYGTGSGSTRPSQRGNNRNGGGAGGVAGGAAGGNGGGFNAGGARGNA 243
            |: |.|..|:.|..|.          ::|:...:.||
Yeast   233 IY-YQPTQFNSVLIDH----------SQPNTIFHQRN---------------------------- 258

  Fly   244 GGRGGADRFGGAAGGAVAGAGMGQRDNPFINPWANGGGGDVDGFGNNAGGAGGFAGNSFGGGAGG 308
                                                                    :.:
Yeast   259 --------------------------------------------------------HQY------ 261

  Fly   309 PFGGGSFGNNGFGGGPSDFGGNSGNFGQAQGTNSLP---SLGSFSQNQGGTSSLPSLGSFGQNPG 370
                          .|||      .....:...:||   :|.|.:..|..|:|:.:..:|..|..
Yeast   262 --------------HPSD------KLLSYKPNKNLPISSTLLSMATPQYTTASVANATAFQPNFV 306

  Fly   371 GPGGLGNGLSGGANGGVGTLGGANGAGGFNAVGGANGGPNGSPNAATNVPQGHDPNNSTQ--VTI 433
            .|             .|..|                .||..||     .|..|...|..|  :.|
Yeast   307 IP-------------NVTVL----------------DGPVISP-----APGNHLLMNFVQQEIFI 337

  Fly   434 PKELAGAIIGKGGGRIRRIRNESSAYITIDEPLPNSNDRIITISGTPKQIQMAQYLLQQSVH--- 495
            .::..|.:|||.|..|..::..:...|.|.:|:..|::|.:||.||....|.|..|:...:.
Yeast   338 DEKFVGNVIGKDGKHINSVKESTGCSIIIQDPVEGSSERRLTIRGTFMASQAAIMLISNKIEIDR 402

  Fly   496 ---ENGRRN 501
               |..||:
Yeast   403 SNAERKRRS 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HnRNP-K	NP_995906.1	KH-I_HNRNPK_rpt1	28..91	CDD:411860	12/68 (18%)
		KH-I_HNRNPK_rpt2	100..170	CDD:411861	22/77 (29%)
		KH-I_HNRNPK_rpt3	426..498	CDD:411862	22/79 (28%)
PBP2	NP_009792.3	KH-I_PCBP_rpt1	69..137	CDD:411866	13/67 (19%)
		KH-I_Rnc1_rpt2	150..218	CDD:411884	21/70 (30%)
		KH-I	334..394	CDD:411802	18/59 (31%)