Protein Alignment HnRNP-K and PCBP4

DIOPT Version :10

• Sequence 1: NP_995906.1
• Gene: HnRNP-K / 43862
• FlyBaseID: FBgn0267791
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_047304568.1
• Gene: PCBP4 / 57060
• HGNCID: 8652
• Length: 426
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 95/479 - (19%)
• Similarity: 153/479 - (31%)
• Gaps: 210/479 - (43%)

  Fly    30 TVRILIPSSIAGAVIGKGGQHIQKMRTQYKATVSVDDSQGPERTIQISADIESTLEIITEMLKYF 94
            |:|:|:.....|::|||.|:.::::|.|..|.:::.:...|||...|:....:....:: |:.:
Human    42 TLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTAAVFHAVS-MIAF- 104

  Fly    95 EERDEDF---------------DVRLLIHQSLAGCVIGKGGQKIKEIRDRIGCRFLKVFSNVAPQ 144
             :.|||.               .:||:|..|..|.:|||.|.||||||:..|.: ::|..::.|.
Human   105 -KLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQ-VQVAGDLLPN 167

  Fly   145 STDRVVQTVGKQSQVIEAVREVITLTRDTPIKGAIHNYDPMNFDRVYADEYGGYGTGSGSTRPSQ 209
            ||:|.|...|....:|..||::..:..::|.|||...|.|            ....|:.....:|
Human   168 STERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHP------------SLSLGTVLLSANQ 220

  Fly   210 RGNNRNGGGAGGVAGGAAGGNGGGFNAGGARGNAGGRGGADRFGGAAGGAVAGAGMGQRDNPFIN 274
                                   ||:..|..                 |||..|.:
Human   221 -----------------------GFSVQGQY-----------------GAVTPAEV--------- 236

  Fly   275 PWANGGGGDVDGFGNNAGGAGGFAGNSFGGGAGGPFGGGSFGNNGFGGGPSDFGGNSGNFGQAQG 339
                                                                             
Human   237 ----------------------------------------------------------------- 236

  Fly   340 TNSLPSLGSFSQNQGGTSSLPSLGSFGQNPGGPGGLGNGLSGGANGGVGTLGGANGAGGFNAVGG 404
                             :.|..|.|                                   :||
Human   237 -----------------TKLQQLSS-----------------------------------HAV-- 247

  Fly   405 ANGGPNGSPNAATNVPQGHDPNNST---QVTIPKELAGAIIGKGGGRIRRIRNESSAYITIDEPL 466
                    |.|..:|..|.||...|   :..:|.:|.|.:||:.|.:|..||..|.|:|.|....
Human   248 --------PFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQA 304

  Fly   467 PNSNDRIITISGTPKQIQMAQYLL 490
            ..:.:|.:||:|:|..|.:||||:
Human   305 EGAGERHVTITGSPVSIALAQYLI 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HnRNP-K	NP_995906.1	KH-I_HNRNPK_rpt1	28..91	CDD:411860	15/60 (25%)
		KH-I_HNRNPK_rpt2	100..170	CDD:411861	27/84 (32%)
		KH-I_HNRNPK_rpt3	426..498	CDD:411862	24/68 (35%)
PCBP4	XP_047304568.1	KH-I_PCBP4_rpt1	40..109	CDD:411945	17/69 (25%)
		KH-I_PCBP4_rpt2	124..195	CDD:411948	26/71 (37%)
		KH-I_PCBP4_rpt3	264..331	CDD:411951	24/65 (37%)