Protein Alignment HnRNP-K and pcbp4

DIOPT Version :10

• Sequence 1: NP_995906.1
• Gene: HnRNP-K / 43862
• FlyBaseID: FBgn0267791
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_998282.2
• Gene: pcbp4 / 406391
• ZFINID: ZDB-GENE-040426-2122
• Length: 464
• Species: Danio rerio
• Alignment Length: 503
• Identity: 117/503 - (23%)
• Similarity: 175/503 - (34%)
• Gaps: 186/503 - (36%)

  Fly     5 LRMKREMNDEGEGPQDQKRNRRNEETVRILIPSSIAGAVIGKGGQHIQKMRTQYKATVSVDDSQG 69
            :||..| .|.|:|..:...      |:|:|:.....|::|||.|:.::::|.:..|.:::.:...
Zfish    10 VRMNCE-QDFGDGGMNVTL------TLRLLMHGKEVGSIIGKKGETVKRIREESSARINISEGSC 67

  Fly    70 PERTIQISADIESTLEIITEMLKYFEE------------RDEDFDVRLLIHQSLAGCVIGKGGQK 122
            |||.|.|:...|......|.:....||            ......:||:|..|..|.:|||||.|
Zfish    68 PERIITITGATECVFRAFTMITIKLEEDLAALVANGTVTSKPPVTLRLVIPASQCGSLIGKGGSK 132

  Fly   123 IKEIRDRIGCRFLKVFSNVAPQSTDRVVQTVGKQSQVIEAVREVITLTRDTPIKGAIHNYDPMNF 187
            |||||::.|.: ::|..::.|.||:|.|...|.|..:|:.|:.:.|:..::|.|||...|
Zfish   133 IKEIREKTGAQ-VQVAGDLLPNSTERGVTISGSQDAIIQCVKLICTVILESPPKGATIPY----- 191

  Fly   188 DRVYADEYGGYGTGSGSTRPSQRGNNRNGGGAGGVAGGAAGGNGGGFNAGGARGNAGGRGGADRF 252
                              |||
Zfish   192 ------------------RPS-------------------------------------------- 194

  Fly   253 GGAAGGAVAGAGMGQRDNPFINPWANGGGGDVDGFGNNAGGAGGFAGNSFGGGAGGPFGGGSFGN 317
              .|.|||.                                   .|||..            |..
Zfish   195 --PAPGAVL-----------------------------------LAGNQV------------FET 210

  Fly   318 NGFGGGPSDFGGNSGNFGQAQGTNSLPSLGSFSQNQGGT--SSLPSLGSFGQNPGGPGGLGNGLS 380
            :.|...|.        |..|||...|....:. |||.|.  |.|..|.......|
Zfish   211 SEFASHPL--------FSVAQGGLDLQQAYTV-QNQYGIPHSELAKLHQLSMQQG---------- 256

  Fly   381 GGANGGVGTLGGANGAGGFNAVGGANGGPNGSPNAATNVPQGHDPNNST---QVTIPKELAGAII 442
                                      .||.....|...:|.|.:.::.|   ::.||.:|.|:||
Zfish   257 --------------------------LGPIAQATATQVLPAGIESSSQTASQELLIPNDLIGSII 295

  Fly   443 GKGGGRIRRIRNESSAYITIDEPLPNSNDRIITISGTPKQIQMAQYLL 490
            |:.|.:|..||..|.|.|.|...|.:::||.:||:|:|..|.:||||:
Zfish   296 GRQGTKINEIRQVSGAQIKIGSQLDSTSDRHVTITGSPISINLAQYLI 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HnRNP-K	NP_995906.1	KH-I_HNRNPK_rpt1	28..91	CDD:411860	17/62 (27%)
		KH-I_HNRNPK_rpt2	100..170	CDD:411861	28/69 (41%)
		KH-I_HNRNPK_rpt3	426..498	CDD:411862	28/68 (41%)
pcbp4	NP_998282.2	KH-I_PCBP4_rpt1	26..95	CDD:411945	18/74 (24%)
		KH-I_PCBP4_rpt2	110..181	CDD:411948	28/71 (39%)
		KH-I_PCBP4_rpt3	279..346	CDD:411951	28/65 (43%)