Protein Alignment fuss and Skor2

DIOPT Version :8

• Sequence 1: NP_001162829.1
• Gene: fuss / 43835
• FlyBaseID: FBgn0039932
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001103213.1
• Gene: Skor2 / 664805
• MGIID: 3645984
• Length: 1008
• Species: Mus musculus
• Alignment Length: 308
• Identity: 187/309 (61%)
• Similarity: 221/309 (72%)
• Gaps: 19/309 (6%)

  Fly    28 RSNHVSSVLLYGVQIVSLHIEGQERLCLAQISNTLLKQFSYNEIHNRRVALGITCVQCTPVQLEI 92
            :.|.|..|:|||:.||||.|:||||||||||||||||.|||||||||||||||||||||||||||
Mouse    37 KPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEI 101

  Fly    93 LRRAGAMPVSSRRCGMITRREAERLCKSFLGDNTPPRLPDDFAFNVQHKCAWGCRGSFLPSRYNS 157
            ||||||||:|||||||||:||||||||||||:|.||:|||:|||:|.|:|||||||||:|:||||
Mouse   102 LRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNS 166

  Fly   158 SRAKCIKCSYCGMFFSPNKFIFHSHRITTNDRYVQPDAANFNSWRRHMSLSGNDYDEKIIHAWED 222
            |||||||||||.|:|||||||||||| |.:.:|.|||||||||||||:.|:.....::::.||||
Mouse   167 SRAKCIKCSYCNMYFSPNKFIFHSHR-TPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWED 230

  Fly   223 VKAMFNGGTRKR-LVGSSINPR-SPGSPTQSTAVSSGVGSSSCGS-----------PTSFERDTN 274
            ||||||||:||| |...|.:|. .|.|..::.||::....:..|.           |........
Mouse   231 VKAMFNGGSRKRALPQPSAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPLA 295

  Fly   275 EVDG--KSGSSLPQRSQIDSQYNYGTVAAAAAVVGVTA---VAAATVG 317
            |:.|  .:....|:....|.......|.|||::....|   |||||.|
Mouse   296 ELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAATGG 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fuss	NP_001162829.1	Ski_Sno	25..123	CDD:280577	82/95 (86%)
		c-SKI_SMAD_bind	135..228	CDD:198114	67/93 (72%)
Skor2	NP_001103213.1	Ski_Sno	39..132	CDD:280577	82/93 (88%)
		c-SKI_SMAD_bind	145..235	CDD:285935	65/91 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_2C3ZR
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0006061
OrthoInspector	1	1.000				T1082423
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR10005
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R5040
TreeFam	1	0.960
	6	5.990