Protein Alignment fuss and SKOR2

DIOPT Version :9

• Sequence 1: NP_001162829.1
• Gene: fuss / 43835
• FlyBaseID: FBgn0039932
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001264992.1
• Gene: SKOR2 / 652991
• HGNCID: 32695
• Length: 1015
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 187/315 - (59%)
• Similarity: 223/315 - (70%)
• Gaps: 32/315 - (10%)

  Fly    28 RSNHVSSVLLYGVQIVSLHIEGQERLCLAQISNTLLKQFSYNEIHNRRVALGITCVQCTPVQLEI 92
            :.|.|..|:|||:.||||.|:||||||||||||||||.|||||||||||||||||||||||||||
Human    37 KPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEI 101

  Fly    93 LRRAGAMPVSSRRCGMITRREAERLCKSFLGDNTPPRLPDDFAFNVQHKCAWGCRGSFLPSRYNS 157
            ||||||||:|||||||||:||||||||||||:|.||:|||:|||:|.|:|||||||||:|:||||
Human   102 LRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNS 166

  Fly   158 SRAKCIKCSYCGMFFSPNKFIFHSHRITTNDRYVQPDAANFNSWRRHMSLSGNDYDEKIIHAWED 222
            |||||||||||.|:|||||||||||| |.:.:|.|||||||||||||:.|:.....::::.||||
Human   167 SRAKCIKCSYCNMYFSPNKFIFHSHR-TPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWED 230

  Fly   223 VKAMFNGGTRKRLVGSSINPRSPGS-----PTQS---------TAVSSG---VGSSSCGSPTSFE 270
            ||||||||:|||.:     |: ||:     |..|         .||:.|   :|....|:|....
Human   231 VKAMFNGGSRKRAL-----PQ-PGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPP 289

  Fly   271 RDTNEVDGKSGS-----SLPQRSQIDSQYNYGTVAAAAAVVGVTA---VAAATVG 317
            .....:...:|:     ..|:....|.......|.|||::....|   ||||:.|
Human   290 PPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGG 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fuss	NP_001162829.1	Ski_Sno	25..123	CDD:280577	81/94 (86%)
		c-SKI_SMAD_bind	135..228	CDD:198114	66/92 (72%)
SKOR2	NP_001264992.1	Ski_Sno	39..132	CDD:280577	81/92 (88%)
		c-SKI_SMAD_bind	145..235	CDD:285935	64/90 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	169	1.000	Domainoid score	I3803
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003480
OrthoInspector	1	1.000	-	-		otm42020
orthoMCL	1	0.900	-	-		OOG6_106258
Panther	1	1.100	-	-	LDO	PTHR10005
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5040
SonicParanoid	1	1.000	-	-		X2371
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.990