Protein Alignment fuss and SKOR2

DIOPT Version :10

• Sequence 1: NP_001162829.1
• Gene: fuss / 43835
• FlyBaseID: FBgn0039932
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001264992.1
• Gene: SKOR2 / 652991
• HGNCID: 32695
• Length: 1015
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 187/315 - (59%)
• Similarity: 223/315 - (70%)
• Gaps: 32/315 - (10%)

  Fly    28 RSNHVSSVLLYGVQIVSLHIEGQERLCLAQISNTLLKQFSYNEIHNRRVALGITCVQCTPVQLEI 92
            :.|.|..|:|||:.||||.|:||||||||||||||||.|||||||||||||||||||||||||||
Human    37 KPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEI 101

  Fly    93 LRRAGAMPVSSRRCGMITRREAERLCKSFLGDNTPPRLPDDFAFNVQHKCAWGCRGSFLPSRYNS 157
            ||||||||:|||||||||:||||||||||||:|.||:|||:|||:|.|:|||||||||:|:||||
Human   102 LRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNS 166

  Fly   158 SRAKCIKCSYCGMFFSPNKFIFHSHRITTNDRYVQPDAANFNSWRRHMSLSGNDYDEKIIHAWED 222
            |||||||||||.|:|||||||||||| |.:.:|.|||||||||||||:.|:.....::::.||||
Human   167 SRAKCIKCSYCNMYFSPNKFIFHSHR-TPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWED 230

  Fly   223 VKAMFNGGTRKRLVGSSINPRSPGS-----PTQS---------TAVSSG---VGSSSCGSPTSFE 270
            ||||||||:|||.:     |: ||:     |..|         .||:.|   :|....|:|....
Human   231 VKAMFNGGSRKRAL-----PQ-PGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPP 289

  Fly   271 RDTNEVDGKSGS-----SLPQRSQIDSQYNYGTVAAAAAVVGVTA---VAAATVG 317
            .....:...:|:     ..|:....|.......|.|||::....|   ||||:.|
Human   290 PPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGG 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fuss	NP_001162829.1	DHD_Skor	32..122	CDD:410783	79/89 (89%)
		c-SKI_SMAD_bind	135..228	CDD:198114	66/92 (72%)
SKOR2	NP_001264992.1	DHD_Skor	41..131	CDD:410783	79/89 (89%)
		c-SKI_SMAD_bind	144..236	CDD:471667	66/92 (72%)