Protein Alignment fuss and Snoo

DIOPT Version :10

• Sequence 1: NP_001162829.1
• Gene: fuss / 43835
• FlyBaseID: FBgn0039932
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_609164.3
• Gene: Snoo / 5740414
• FlyBaseID: FBgn0085450
• Length: 1223
• Species: Drosophila melanogaster
• Alignment Length: 739
• Identity: 155/739 - (20%)
• Similarity: 255/739 - (34%)
• Gaps: 220/739 - (29%)

  Fly    37 LYGVQIVSLHIEGQERLCLAQISNTLLKQFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPV 101
            |.|..|....:.|:.||||.|..|.:|..||..:|:.....|||.|.|||..||...:.|..:|.
  Fly   121 LEGKTIGCFSVGGEMRLCLPQFLNNVLNDFSLEQINRIFDELGIYCSQCTHDQLVEFKAAKILPS 185

  Fly   102 SSRRCGMITRREAERLCKSFL-GDNTPPRLPDD------FAFNVQHKCAWGCRGSFLPSRYNSSR 159
            ..:..|:|||.:|||||.:.| ..:....:|.:      .:|:|.|||...|.|...|..|:..:
  Fly   186 DVKASGLITRTDAERLCAALLHRSDRNSYVPIESLAKGALSFHVYHKCFGKCEGICTPDMYSYQK 250

  Fly   160 AKCIKCSYCGMFFSPNKFIFHSHRITTNDR-YVQPDAANFNSWRRHMSLSGNDYDE--------K 215
            ..||||..|..:|||.||:.|.||...|.. :...|:.|::.: .|::|...:.::        |
  Fly   251 PTCIKCLECDGWFSPQKFVGHVHRKFENHTCHWGFDSRNWHDY-LHVALDVENREKYQIILDQLK 314

  Fly   216 IIHAWEDVKAMFNGGTRKR-------------------------LVGSSINPRSPGSPTQSTAVS 255
            .:...|..||......:||                         |||:...|..|........:.
  Fly   315 EVELKEMHKAQRELEHKKRKAEMLMDDGMLGSGPVLGLAGHPHGLVGALAPPPPPPMKQPQMDIP 379

  Fly   256 SG-------VGSSSCGSPTSF------------ERDTNEVDGKSGSSLPQRSQIDSQYNYGTVAA 301
            ||       .|::...|...:            ||:      :....||....:..|:.
  Fly   380 SGKKQLQQLKGATVAASALEYQYQVMYAHCVQKERE------REREHLPHSHPLPRQHR------ 432

  Fly   302 AAAVVGVTAVAAATVGVP----------------------------FNLHGSTV----------- 327
                    ||..||...|                            .:.:|:|:
  Fly   433 --------AVLVATTPYPHLPQYPTPPTLNSSSAFRPWGPDTTKAFLHAYGATLSSLPYACQEPP 489

  Fly   328 --------------------------LSPLHS-LRNERDLSIMPISRNFVVDYMWQQKDQHYQQP 365
                                      |:|..| |..|||.....:.|..:.....::|:..:|..
  Fly   490 ELQNPERVVRSTDKRYAERTYQPNVALAPRKSILSKERDKDRERMEREVMERQRLREKETDHQVV 554

  Fly   366 YARK-------IPSGDNSDS---SLDFDSWVKP------DSNNPIP------------------- 395
            :.::       .|:....|.   .||.   |:|      .||:|:|
  Fly   555 HIKQERSQTPTPPTASPPDGVVLPLDV---VEPPHPSSSGSNSPLPAHLPAAPATAPPNAGGAPP 616

  Fly   396 ---NANSVRTSDNCSFNIKNE--SHSSIYGIIKNHKLSGVPNSGLNLSDYNIPSILNCSAFKPVV 455
               |..::|:.:..|....||  |.:|.:....:|.....|.:|......:|.:.:|..| |.:.
  Fly   617 TPTNLRNMRSPEEFSAGGSNEITSSTSPHHQQSSHHQVVQPTAGAPPPSQHIIATVNQHA-KLLP 680

  Fly   456 ASTAIV----STSLYTRSNESTRTDCNNPAQSTRTTTVLTHNSISASSHQIVGHKTFSPILGKIH 516
            :|:::.    |:||...:||.:|...|....|.:  .|:..:.::...||  .|.|.   :....
  Fly   681 SSSSLPNGNGSSSLAATNNEPSRIRINKNLMSQQ--PVVAVSGMTPHHHQ--HHPTH---MHHFS 738

  Fly   517 SNPEKNRIVSVFASSSTGNADDNDDDDEVVDIETTEDEGKFTVQHADSPKTQYDAISGSDSPSRS 581
            ....|::..|...|||.|           :::.|.......:..||..|||.:.::...:...::
  Fly   739 HGYYKSQASSPTQSSSAG-----------LNLSTHSSNVVSSPHHATQPKTHHSSVGSGNHGLQN 792

  Fly   582 PSTSTNIDVEQDVDVDIITTDTED 605
            .......:.|       ::|||:|
  Fly   793 GKPHLGSEFE-------LSTDTDD 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fuss	NP_001162829.1	DHD_Skor	32..122	CDD:410783	34/84 (40%)
		c-SKI_SMAD_bind	135..228	CDD:198114	31/101 (31%)
Snoo	NP_609164.3	DHD_Ski_Sno	116..206	CDD:410782	34/84 (40%)
		c-SKI_SMAD_bind	226..317	CDD:198114	28/91 (31%)
		AF-4	637..>789	CDD:461550	36/170 (21%)