Protein Alignment fuss and daf-5

DIOPT Version :10

• Sequence 1: NP_001162829.1
• Gene: fuss / 43835
• FlyBaseID: FBgn0039932
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_496941.1
• Gene: daf-5 / 175054
• WormBaseID: WBGene00000901
• Length: 627
• Species: Caenorhabditis elegans
• Alignment Length: 268
• Identity: 51/268 - (19%)
• Similarity: 93/268 - (34%)
• Gaps: 74/268 - (27%)

  Fly    35 VLLYGVQIVSLHIEGQERLCLAQISNTLLK-----QFSY-NEIHNRRVALGITCVQCTPVQLEIL 93
            :.|.||::.:|.|:|:..|.:..:.:.|.|     |.|: |.:..:.|.:.:    .:|.|..
 Worm    78 IWLLGVRVPALSIDGEPHLPIEILDDMLTKKDKKDQMSFQNLLRYKNVYIRM----ASPSQFR-- 136

  Fly    94 RRAGAMPVSSRRC--------GMITRREAERL--------------------------------- 117
                |:...|:.|        .:::|.:.||:
 Worm   137 ----AVMEKSKECENLNITSLSLMSRSDIERIMGELRLESMLTLAEHDNWDISDRVHVVHVNFID 197

  Fly   118 -CKSFLGDNTPPRLPDDFAFNVQHKCAWGCRGSFLPSRYNSSRAKCIKCSYCGMFFSPNKFIFHS 181
             |..:|..       ||...:|...   |..|.:..:|.|   .:||:|.:|...|:|..||.|.
 Worm   198 YCSEWLES-------DDLEEDVMQS---GTHGYWYKNRRN---MRCIECQHCEGKFTPTDFIMHH 249

  Fly   182 HRITTNDRYVQPDAANFNSWRRHMSLSGNDYDEKIIHAWEDVKAMFNGGTRKRLVGSSINPRSPG 246
            |.......:|.....:| .|.|.:.:.  |...:.:.||.......:...::....::.:...|.
 Worm   250 HYPIKPSGFVHTGCNSF-QWIRLIEVF--DKSNENLEAWNKFVLNSHRAGKREYDEAAPHQAPPK 311

  Fly   247 SPTQSTAV 254
            .|...|.|
 Worm   312 RPAMETPV 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fuss	NP_001162829.1	DHD_Skor	32..122	CDD:410783	22/134 (16%)
		c-SKI_SMAD_bind	135..228	CDD:198114	22/92 (24%)
daf-5	NP_496941.1	c-SKI_SMAD_bind	<229..288	CDD:471667	17/61 (28%)