Protein Alignment fuss and skor1a

DIOPT Version :9

• Sequence 1: NP_001162829.1
• Gene: fuss / 43835
• FlyBaseID: FBgn0039932
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001124124.1
• Gene: skor1a / 100170817
• ZFINID: ZDB-GENE-080722-5
• Length: 751
• Species: Danio rerio
• Alignment Length: 799
• Identity: 274/799 - (34%)
• Similarity: 378/799 - (47%)
• Gaps: 187/799 - (23%)

  Fly    25 TSQRSNHVSSVLLYGVQIVSLHIEGQERLCLAQISNTLLKQFSYNEIHNRRVALGITCVQCTPVQ 89
            :|.:.|.||...||||.||||.|:||||||||||||||||.:|||||||||||||||||||||||
Zfish    31 SSMKPNQVSETALYGVPIVSLVIDGQERLCLAQISNTLLKNYSYNEIHNRRVALGITCVQCTPVQ 95

  Fly    90 LEILRRAGAMPVSSRRCGMITRREAERLCKSFLGDNTPPRLPDDFAFNVQHKCAWGCRGSFLPSR 154
            |||||||||||:|||||||||:||||||||||||.:.||:||::|||:|.|:|||||||:|:|:|
Zfish    96 LEILRRAGAMPISSRRCGMITKREAERLCKSFLGAHNPPKLPENFAFDVSHECAWGCRGNFIPAR 160

  Fly   155 YNSSRAKCIKCSYCGMFFSPNKFIFHSHRITTNDRYVQPDAANFNSWRRHMSLSGNDYDEKIIHA 219
            |||||||||||:||.|:|||||||||||| |...:|.|||||||||||||:.|:.....:.:.||
Zfish   161 YNSSRAKCIKCTYCNMYFSPNKFIFHSHR-TPESKYTQPDAANFNSWRRHLKLTDKSLADDLCHA 224

  Fly   220 WEDVKAMFNGGTRKRL-------VGSSINPRSPGSPTQSTAVSSGVGSSSCGSPTSFERDTNEVD 277
            |||||||||||:|||.       :.|.:.|:|.|:.||:|:             :.....|...|
Zfish   225 WEDVKAMFNGGSRKRAMPGSGSEMSSHLKPQSSGNITQTTS-------------SDIPHKTLRCD 276

  Fly   278 GKSGSSLPQRSQIDSQYNYGTVAAAAAVVGVTAVAAATVGVPFNLHGSTVLSPLHSLRNERDLSI 342
            ...|:    .|..:|..||..:...:...|:..      .:|..:.......|...|..::|..:
Zfish   277 DDRGN----LSLSNSVRNYPVIPVPSKSFGMLQ------KIPPPIFPHPYSFPAFGLCQKKDDGV 331

  Fly   343 MPISRNFVVDYMWQ-QKDQHYQQ-----PYARKIP-------------SGDNSDSSLDFDSWVKP 388
            ...::..|....|. .||..|..     |.|..:|             .|..:::.:   |..:.
Zfish   332 GEQNKTNVPSVFWPGAKDGIYPSFPMFWPTAGSLPLSSYQPKPHADLLGGRQTEAEI---SESER 393

  Fly   389 DSNNPIPNANSVRTSDNCSF--NIKN-------ESHSSIYGIIKNHKLSGVPNSGLNLSDYNIPS 444
            ..|.|   .:|:..|:.||.  :::|       |:.||          .|.|::...||
Zfish   394 GGNTP---RDSLFDSERCSSSQSLRNDEDKSGDEARSS----------EGQPSTPRKLS------ 439

  Fly   445 ILNCSAFKPVVASTAIVSTSLYTRSNESTRTDCNNPAQSTRTTTVLTHNSISASSHQIVGHKTFS 509
              ..|||:|||.....:: .||.          |..|.|......|:.:.:|.||    .:::.|
Zfish   440 --YISAFRPVVKDAESIA-KLYG----------NRDAYSGAHPGHLSPDFVSESS----SYRSAS 487

  Fly   510 PILGKIHSNPEKNRIVSVFASSSTGNADDNDDDDEVVDIET-----TEDEGKFTVQHADSPKTQY 569
            |.                        ||..::.|  ||:||     .|:..:.:|....||..:
Zfish   488 PC------------------------ADSGEEPD--VDVETHRIPDDEESIQLSVDDRQSPVRE- 525

  Fly   570 DAISGSDSPSRSP---------STSTNIDVEQDVDV----DIITTDTEDQLELSVGRYSTENTSH 621
                  |:|:..|         |.|.:.|.:|:..|    |.|..|.          ||.|....
Zfish   526 ------DTPTPQPDDDHQTVTFSDSGSPDHKQNKQVAKKSDAIAYDV----------YSHEKDGA 574

  Fly   622 SL-SFFQAEKIQISDLSPNTKTSSGDNET-NTLKDAKGINGNLQILARRKRNKLQKDRCLSKRTV 684
            || :.......::|..:.:|..|...|.| :..:..|..:..:::   .:.|.:  |..|  |:.
Zfish   575 SLQNTLSCSASKLSRCAQDTNDSHISNSTDDECESQKSCSDQIRV---SRENSI--DAAL--RST 632

  Fly   685 SKCVSDKSLIKGLAANELSSSLQIQQHVAFPVFLKSQLHSLRP-----------------QQAQQ 732
            ....:.:..|:.:|..||..  |:.:.|.....|:.:..||:.                 ||.|.
Zfish   633 DNRFNFEKDIENMAKEELQK--QLLEQVELRKKLEREFQSLKDNFQDQMKRELSYREEMVQQLQI 695

  Fly   733 VVSLTTNSVAESNKWSYPV 751
            |.....|.:.:..|..|.:
Zfish   696 VRDTLCNELDQERKARYAI 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fuss	NP_001162829.1	Ski_Sno	25..123	CDD:280577	82/97 (85%)
		c-SKI_SMAD_bind	135..228	CDD:198114	65/92 (71%)
skor1a	NP_001124124.1	Ski_Sno	36..129	CDD:280577	81/92 (88%)
		c-SKI_SMAD_bind	142..232	CDD:285935	63/90 (70%)
		RILP-like	<648..727	CDD:304877	14/69 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	169	1.000	Domainoid score	I3767
eggNOG	1	0.900	-	-		E1_2C3ZR
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003480
OrthoInspector	1	1.000	-	-		otm25922
orthoMCL	1	0.900	-	-		OOG6_106258
Panther	1	1.100	-	-	O	PTHR10005
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5040
SonicParanoid	1	1.000	-	-		X2371
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.800