DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pho and Nacc2

DIOPT Version :9

Sequence 1:	NP_524630.1	Gene:	pho / 43819	FlyBaseID:	FBgn0002521	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001032175.1	Gene:	Nacc2 / 67991	MGIID:	1915241	Length:	586	Species:	Mus musculus

Alignment Length:	223	Identity:	46/223 - (20%)
Similarity:	70/223 - (31%)	Gaps:	78/223 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 GASDLLKGKEEFGIDGFTSQQNKEYQKMESKFTNAQTLEMPHPISSVQIMDHLIKERGNLSQENN 248
            |||.|..      .|..||..|:|.::.:..:..         :...|.....||..||.:
Mouse   248 GASSLPT------TDSPTSYHNEEDEEDDEAYDT---------MVEEQYGQMYIKATGNYA---- 293

  Fly   249 ISERILSKTTLSFEEPILLPDSSSIELVNETAAMTINNHRTLSNHTGNTGDLHALPSSVPFRIGL 313
            :.|:         .||:.| :|.|..|:..                    ||.|||:|:..:||.
Mouse   294 VQEK---------PEPVPL-ESRSCVLIRR--------------------DLVALPASLISQIGY 328

  Fly   314 H-------EGQVNDCLSTISQSTHQDNTDSTGCGEMNLSEVTVSYTNDKKIACPHKGCNKHFRDS 371
            .       ||...:.|..::           |.|        |..|..:.:.|......||   .
Mouse   329 RCHPKLYSEGDPGEKLELVA-----------GSG--------VYITRGQLMNCHLCAGVKH---K 371

  Fly   372 SAMRKHLHTHGPRVHVCAECGKAFVESS 399
            ..:|:.|.|...|..:...||.....|:
Mouse   372 VLLRRLLATFFDRNTLANSCGTGIRSST 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pho	NP_524630.1	Transpos_assoc	<342..382	CDD:290671	8/39 (21%)
		C2H2 Zn finger	359..381	CDD:275368	5/21 (24%)
		COG5048	<386..515	CDD:227381	3/14 (21%)
		zf-C2H2	386..408	CDD:278523	3/14 (21%)
		C2H2 Zn finger	388..408	CDD:275368	3/12 (25%)
		zf-H2C2_2	401..426	CDD:290200
		C2H2 Zn finger	416..438	CDD:275368
		zf-H2C2_2	430..457	CDD:290200
		C2H2 Zn finger	446..468	CDD:275368
Nacc2	NP_001032175.1	BTB_POZ_BTBD14A_NAC2	1..131	CDD:349598
		Prog_receptor	<139..241	CDD:366948
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	177..196
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	236..272		9/29 (31%)
		BEN	371..448	CDD:214981	7/29 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	542..586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910