DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pho and AgaP_AGAP008796

DIOPT Version :9

Sequence 1:	NP_524630.1	Gene:	pho / 43819	FlyBaseID:	FBgn0002521	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_557956.3	Gene:	AgaP_AGAP008796 / 1275653	VectorBaseID:	AGAP008796	Length:	648	Species:	Anopheles gambiae

Alignment Length:	231	Identity:	61/231 - (26%)
Similarity:	93/231 - (40%)	Gaps:	60/231 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 HTGNTG-DLHALPSSVPFRIGLHEGQVNDCLSTISQSTHQDNTDSTGCGEMNLSEVTVSYTNDKK 356
            |||... ..|..|.:.     :|.||:         :||                 ...:.|::.
Mosquito   203 HTGERPFACHLCPKTF-----VHAGQL---------ATH-----------------IARHNNERG 236

  Fly   357 IACPHKGCNKHFRDSSAMRKHLHTHGP----RVHVCAECGKAFVESSKLKRH-QLVHTGEKPFQC 416
            ..|..  |.|.|...:.:|:||.||..    :....|:||:.|..:.:|:|| ::.|:.|.||:|
Mosquito   237 HRCSQ--CGKAFYSKAMLRQHLETHETHETRKASNAAKCGRRFARACELRRHRRIYHSSEHPFRC 299

  Fly   417 TFEGCGKRFSLDFNLRTHVRIHTGDRPFVCPFDACNKKFAQSTNLKSHILTHAKAKRNTSISGKS 481
              |.|||.|....:.|.|:..|...|.|.|  :.|:|||.:..||.:|.::|
Mosquito   300 --EPCGKTFLSSQSYREHMDSHANVRRFEC--EVCDKKFVRRRNLVNHRMSH------------- 347

  Fly   482 GCSNAESNSQSEDTSANYVKV--ELQDSVTENHVPF 515
              :|.....|.|...|..:|.  .||:....:|.||
Mosquito   348 --TNQRPICQVEGGPARTLKTISSLQNHFRSHHYPF 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pho	NP_524630.1	Transpos_assoc	<342..382	CDD:290671	9/39 (23%)
		C2H2 Zn finger	359..381	CDD:275368	7/21 (33%)
		COG5048	<386..515	CDD:227381	39/131 (30%)
		zf-C2H2	386..408	CDD:278523	7/22 (32%)
		C2H2 Zn finger	388..408	CDD:275368	7/20 (35%)
		zf-H2C2_2	401..426	CDD:290200	12/25 (48%)
		C2H2 Zn finger	416..438	CDD:275368	8/21 (38%)
		zf-H2C2_2	430..457	CDD:290200	10/26 (38%)
		C2H2 Zn finger	446..468	CDD:275368	8/21 (38%)
AgaP_AGAP008796	XP_557956.3	C2H2 Zn finger	38..58	CDD:275368
		COG5048	<63..251	CDD:227381	15/80 (19%)
		C2H2 Zn finger	68..88	CDD:275368
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..142	CDD:275368
		C2H2 Zn finger	153..173	CDD:275368
		C2H2 Zn finger	183..203	CDD:275368	61/231 (26%)
		C2H2 Zn finger	211..231	CDD:275368	7/50 (14%)
		C2H2 Zn finger	239..259	CDD:275368	7/21 (33%)
		C2H2 Zn finger	273..291	CDD:275368	6/17 (35%)
		C2H2 Zn finger	299..319	CDD:275368	8/21 (38%)
		C2H2 Zn finger	327..347	CDD:275368	8/21 (38%)
		C2H2 Zn finger	383..403	CDD:275368
		C2H2 Zn finger	410..430	CDD:275368
		C2H2 Zn finger	440..460	CDD:275368
		C2H2 Zn finger	468..488	CDD:275368
		C2H2 Zn finger	576..596	CDD:275368
		zf-H2C2_2	589..613	CDD:290200
		C2H2 Zn finger	604..624	CDD:275368
		C2H2 Zn finger	632..648	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910