Protein Alignment ey and pax7b

DIOPT Version :10

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_073794722.1
• Gene: pax7b / 566533
• ZFINID: ZDB-GENE-080917-54
• Length: 520
• Species: Danio rerio
• Alignment Length: 801
• Identity: 199/801 - (24%)
• Similarity: 281/801 - (35%)
• Gaps: 364/801 - (45%)

  Fly   101 VNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIG 165
            ||||||||:.|||||:..|.||||:||.|.|||.|||.|:||:|||||||.||.|||||||.|||
Zfish    52 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIG 116

  Fly   166 GSKPR-VATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIP-----SVSSINRVLRNLA 224
            ||||| |||.:|..:|.:||||.|.:|:|||||:||::.||....:|     |||||:||||...
Zfish   117 GSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRSTVPSGEASSVSSISRVLRARF 181

  Fly   225 AQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGA 289
            .:|:.:........|.     ..|...||.|.:     |.:|.:...:|
Zfish   182 GKKDDEDDCDKKDDTG-----EKKTKHSIDGIL-----GDKGRMDEVSD---------------- 220

  Fly   290 SNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQ 354
                                                                             
Zfish   221 ----------------------------------------------------------------- 220

  Fly   355 HQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNC 419
                                    :.|.|:
Zfish   221 ------------------------VESEPD----------------------------------- 226

  Fly   420 PVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQID 484
                                                         |.||||.:|:||:||.:|::
Zfish   227 ---------------------------------------------LPLKRKQRRSRTTFTAEQLE 246

  Fly   485 SLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSS 549
            .|||.||||||||::.||.||.:..|.|||:|||||||||:||::            .||
Zfish   247 ELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ------------AGA----- 294

  Fly   550 STSATASLTDSPNSLSACSSLLSGS---AGGPSVST--INGLSSPSTLSTNVNAPTLGAGIDSS- 608
                        |.|:|.:.||.|.   .|.|::.|  :...|.|:|        ||...:..:
Zfish   295 ------------NQLAAFNHLLPGGFPPTGMPTLPTYQLPESSYPTT--------TLPQDVSGTV 339

  Fly   609 ESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRL 673
            ..|.|:|   ||  :.:..|..|:.               .:.:.:.||.|:
Zfish   340 HRPQPLP---PS--TMHQGGLSSDS---------------SSAYGLSSNRHS------------- 371

  Fly   674 NFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPS-FNHSAVGPLAPPS---PIPQQGDLTPSSLYP 734
                      :|:...|.:|.|.|...:.|:.: .:...:..|:.||   |.||.    ..|:.|
Zfish   372 ----------FSSYTDTFMSQSASSNHMNPVSNGLSPQVMSILSNPSAVAPQPQH----EFSISP 422

  Fly   735 CHMTLRPPPMAPAHHHIVPGDGGRPAGVGLGSGQSAN-LGASCSGSGYEVLSAYALPPPPMASSS 798
            .|.:|                            :::| :.||||.....:.:|.:||.
Zfish   423 LHSSL----------------------------EASNPISASCSQRSEPIKTADSLPS------- 452

  Fly   799 AADSSFSAASSASANVTPHHTIAQESCPSPCSSASHFGVAHSSGFSSDPISPA--VSSYAHMSYN 861
                                  :|..||...|:.|         :|.||::..  .|.|...:.:
Zfish   453 ----------------------SQSYCPPTYSTTS---------YSVDPVTAGYQYSQYGQTAVD 486

  Fly   862 YASSANTMTPSSASGTSAHVA 882
            |.:...:::.........|.|
Zfish   487 YLAKNVSLSTQRRMKLGEHSA 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	82/125 (66%)
		Homeodomain	473..528	CDD:459649	35/54 (65%)
pax7b	XP_073794722.1	None