Protein Alignment CG11360 and Mex3a

DIOPT Version :10

• Sequence 1: NP_651934.2
• Gene: CG11360 / 43810
• FlyBaseID: FBgn0039920
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_001025061.2
• Gene: Mex3a / 72640
• MGIID: 1919890
• Length: 520
• Species: Mus musculus
• Alignment Length: 624
• Identity: 230/624 - (36%)
• Similarity: 288/624 - (46%)
• Gaps: 176/624 - (28%)

  Fly    43 LSDDPRTLQLAL-ELSLVGFND-------------NQNCYAQPA-----QPLPMPLSARSDFEIG 88
            |.:|.|.||||| :|.|:|..:             .....||||     .|.|.|.:|.:.....
Mouse    31 LLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAAPAAPSAA 95

  Fly    89 TINSTLPIPSAPN-------CLLLPNAGAVSSEDRSKKSQNMTECVPVPSSEHVAEIVGRQGCKI 146
            ....|...|:||.       |.|...|     |.|.|.|.|.|||||||:|||||||||||||||
Mouse    96 PAAQTPQPPTAPKGANDAKLCALYKEA-----ELRLKGSSNTTECVPVPTSEHVAEIVGRQGCKI 155

  Fly   147 KALRAKTNTYIKTPVRGEEPVFVVTGRKEDVNKAKREILSAADHFSLIRASRKPVSDSQNNGMVG 211
            ||||||||||||||||||||||:||||:|||..|:|||:|||:|||:|||||
Mouse   156 KALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASR------------- 207

  Fly   212 STTSSGGGAVPRMSGPPCMPGQVTIQVRVPYRVVGLVVGPKGATIKHIQQETQTYIVTPSREKEP 276
               :..|.|   ....|.:||||||:||||||||||||||||||||.|||:|.|||:||||:::|
Mouse   208 ---NKSGAA---FGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDP 266

  Fly   277 IFEVTGLPDNVDTARKQIEAHIALRTG---SGSGSGDAITMQSSDSVDTKEYASLPSLTQILNDD 338
            :||:||.|.||:.||::||.|||:|||   ..:..||.:......::|::
Mouse   267 VFEITGAPGNVERAREEIETHIAVRTGKILEYNSDGDFLAGSPDAALDSR--------------- 316

  Fly   339 LNSEILSSIYKNSVPSTQ---EYANNSMKTVVNVSNSVKLVQGHHTGNCFQKSEFAEMEMTANIT 400
                 .|..::...|..:   .:..||:..:               |.|...|.|....::....
Mouse   317 -----YSDAWRVHAPGCKPLSTFRQNSLGCI---------------GECGVDSAFEAPRLSEQGG 361

  Fly   401 AADILDKRLPGNEVSVPLAKANVANIVFRTTSSKTLSFCPP--------TSTSASFHSNCNANIL 457
            .........||..|    .|.:|...|..|:        ||        |.||..|
Mouse   362 DFGYSGYLFPGYGV----GKQDVYYGVAETS--------PPLWAGQENATPTSVLF--------- 405

  Fly   458 TRSCSSASSTTSTKSTNNSANTPPEILNIWKSISDSIDVDEGIGDSPSIWNQPANIIPTAHCSPT 522
                |||||::|:.    .|...|                                 |.||.||.
Mouse   406 ----SSASSSSSSA----KARAGP---------------------------------PGAHRSPA 429

  Fly   523 ISISPTDSLLGMGEHSANQQNLNHAKEPIMPNLPQKIKGIQVQSNADNFLTHRECFVCNENTVTT 587
            .|..| :.|.|:......        ||:.........|::...:.      |:|.||.|:.||.
Mouse   430 TSAGP-EQLTGLPRRPPG--------EPLQGFSKLGTGGLRSPGSG------RDCMVCFESEVTA 479

  Fly   588 ALVPCGHNMFCMECANHICLSMDAVCPVCNSIVYHAMRI 626
            ||||||||:||||||..||...|..||||:.....|:||
Mouse   480 ALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRI 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11360	NP_651934.2	KH-I_MEX3_rpt1	123..195	CDD:411851	61/71 (86%)
		KH-I_MEX3_rpt2	231..302	CDD:411852	52/70 (74%)
		PEX10	<515..621	CDD:227861	40/105 (38%)
		RING-HC_MEX3	575..627	CDD:438181	31/52 (60%)
Mex3a	NP_001025061.2	KH-I_MEX3_rpt1	132..204	CDD:411851	61/71 (86%)
		KH-I_MEX3_rpt2	221..292	CDD:411852	52/70 (74%)
		RING-HC_MEX3A	465..520	CDD:438380	31/60 (52%)