Protein Alignment CG11360 and mex3b

DIOPT Version :10

• Sequence 1: NP_651934.2
• Gene: CG11360 / 43810
• FlyBaseID: FBgn0039920
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_001074462.1
• Gene: mex3b / 569582
• ZFINID: ZDB-GENE-030131-2628
• Length: 537
• Species: Danio rerio
• Alignment Length: 626
• Identity: 240/626 - (38%)
• Similarity: 322/626 - (51%)
• Gaps: 156/626 - (24%)

  Fly    45 DDPRTLQLAL-ELSLVGFNDNQNCYAQPAQPLPMPLSARSDFEIGTINSTLPIPSAPNCLLLPNA 108
            ||.|.||:|| :|||:|.::::|
Zfish    22 DDQRALQIALDQLSLLGLDNDEN------------------------------------------ 44

  Fly   109 GAVSSEDRSKKSQNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGR 173
             ::...:..|||.||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    45 -SLYDNEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGR 108

  Fly   174 KEDVNKAKREILSAADHFSLIRASRKPVSDSQNNGMVGSTTSSGGGAVPRMSGPPCMPGQVTIQV 238
            :|||..|:|||:|||:|||:|||||     ::|:.:.|:.|      ||   |||.:|||.||||
Zfish   109 REDVAMARREIISAAEHFSMIRASR-----NKNSSLNGNAT------VP---GPPNLPGQTTIQV 159

  Fly   239 RVPYRVVGLVVGPKGATIKHIQQETQTYIVTPSREKEPIFEVTGLPDNVDTARKQIEAHIALRTG 303
            |||||||||||||||||||.|||:|.||||||||:|||:|||||:|:|||.||::||||||:|||
Zfish   160 RVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIAMRTG 224

  Fly   304 S-----------GSGSGDAITMQSSDSVDTKEYASL------PSLTQILNDDLNSEILSSIYKNS 351
            .           .:|:.....:..:.|:.:|..:|:      .:.:...||  :|..|.|
Zfish   225 GLIEFTDENDFHANGTDVGFDLHGNASLWSKASSSVTPTSGRKTFSNYRND--SSSSLGS----- 282

  Fly   352 VPSTQEY--ANNSMKTVVNVSNSVKLVQGHHTGNCFQKSEFAEMEMTAN-------ITAADILD- 406
             .||..|  .|||...:.:.|.....:....:.|....:....|...||       :.:.|..|
Zfish   283 -ASTDSYFGGNNSSSRMADYSPPSPALSYTASSNGNNNNNNINMNANANGFVYSGEVISPDCTDL 346

  Fly   407 --KRLPGNEVSVPLAKANVANIVFRTTSSKTLSFCPPTSTSASFHSNCNANILTR--------SC 461
              :..||.:.:.  |...:....:...::.|.:..|..||:||  :|.|..:|..        .|
Zfish   347 TFESSPGFDPTP--APPGLMWSQYERANNGTPASSPVFSTNAS--TNANNGLLAGQRRVNNGVGC 407

  Fly   462 SSASSTTSTKSTNNSANTPPEILNIWKSISDSIDVDEGIGD------SPSIWNQPANIIPTAHCS 520
            :|...:.....:||||...|        ::..:..|.|.|.      ||        ::|.:| .
Zfish   408 TSQRLSPPLHQSNNSATEHP--------LARRVRSDPGGGTLSFPGYSP--------VLPGSH-H 455

  Fly   521 PTISISPTDSLLGMGEHSANQQNLNHAKEPIMPNLPQKIKGIQVQSNADNFLTHRECFVCNENTV 585
            |.:   |:||.:.....|::..:...::           ||            .|:|.||.|:.|
Zfish   456 PGV---PSDSSISSSSSSSSSSSSGTSR-----------KG------------SRDCSVCFESEV 494

  Fly   586 TTALVPCGHNMFCMECANHICLSMDAVCPVCNSIVYHAMRI 626
            ..||||||||:|||||||.||...:..||||::.|..|:||
Zfish   495 IAALVPCGHNLFCMECANRICERNEPKCPVCHAAVTQAIRI 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11360	NP_651934.2	KH-I_MEX3_rpt1	123..195	CDD:411851	64/71 (90%)
		KH-I_MEX3_rpt2	231..302	CDD:411852	58/70 (83%)
		PEX10	<515..621	CDD:227861	36/105 (34%)
		RING-HC_MEX3	575..627	CDD:438181	31/52 (60%)
mex3b	NP_001074462.1	KH-I_MEX3_rpt1	58..130	CDD:411851	64/71 (90%)
		KH-I_MEX3_rpt2	152..223	CDD:411852	58/70 (83%)
		RING-HC_MEX3B	480..537	CDD:438381	33/79 (42%)