Protein Alignment CG11360 and Mex3a

DIOPT Version :10

• Sequence 1: NP_651934.2
• Gene: CG11360 / 43810
• FlyBaseID: FBgn0039920
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_001385668.1
• Gene: Mex3a / 310631
• RGDID: 1564904
• Length: 520
• Species: Rattus norvegicus
• Alignment Length: 627
• Identity: 232/627 - (37%)
• Similarity: 288/627 - (45%)
• Gaps: 182/627 - (29%)

  Fly    43 LSDDPRTLQLAL-ELSLVGFND-------------NQNCYAQPA-----QPLPMPLSARSDFEIG 88
            |.:|.|.||||| :|.|:|..:             .....||||     .|.|.|.:|.:.....
  Rat    31 LLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAAPAAPSAA 95

  Fly    89 TINSTLPIPSAPN-------CLLLPNAGAVSSEDRSKKSQNMTECVPVPSSEHVAEIVGRQGCKI 146
            ....|...|:||.       |.|...|     |.|.|.|.|.|||||||:|||||||||||||||
  Rat    96 PAAQTPQPPTAPKGANDAKLCALYKEA-----ELRLKGSSNTTECVPVPTSEHVAEIVGRQGCKI 155

  Fly   147 KALRAKTNTYIKTPVRGEEPVFVVTGRKEDVNKAKREILSAADHFSLIRASRKPVSDSQNNGMVG 211
            ||||||||||||||||||||||:||||:|||..|:|||:|||:|||:|||||
  Rat   156 KALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASR------------- 207

  Fly   212 STTSSGGGAVPRMSGPPCMPGQVTIQVRVPYRVVGLVVGPKGATIKHIQQETQTYIVTPSREKEP 276
               :..|.|   ....|.:||||||:||||||||||||||||||||.|||:|.|||:||||:::|
  Rat   208 ---NKSGAA---FGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDP 266

  Fly   277 IFEVTGLPDNVDTARKQIEAHIALRTG---SGSGSGDAITMQSSDSVDTKEYASLPSLTQILNDD 338
            :||:||.|.||:.||::||.|||:|||   ..:..||.:......::|::
  Rat   267 VFEITGAPGNVERAREEIETHIAVRTGKILEYNSDGDFLAGSPDAALDSR--------------- 316

  Fly   339 LNSEILSSIYKNSVPSTQ---EYANNSMKTVVNVSNSVKLVQGHHTGNCFQKSEFAEM---EMTA 397
                 .|..::...|..:   .:..||:..:               |.|...|.|...   |...
  Rat   317 -----YSDAWRVHAPGCKPLSTFRQNSLGCI---------------GECGVDSAFEAPRLGEQGG 361

  Fly   398 NITAADILDKRLPGNEVSVPLAKANVANIVFRTTSSKTLSFCPP--------TSTSASFHSNCNA 454
            :......|   .||..|    .|.:|...|..|:        ||        |.||..|
  Rat   362 DFGYGGYL---FPGYGV----GKQDVYYGVAETS--------PPLWAGQENATPTSVLF------ 405

  Fly   455 NILTRSCSSASSTTSTKSTNNSANTPPEILNIWKSISDSIDVDEGIGDSPSIWNQPANIIPTAHC 519
                   |||||::|:.    .|...|                                 |.||.
  Rat   406 -------SSASSSSSSA----KARAGP---------------------------------PGAHR 426

  Fly   520 SPTISISPTDSLLGMGEHSANQQNLNHAKEPIMPNLPQKIKGIQVQSNADNFLTHRECFVCNENT 584
            ||..|..| :.|.|:......        ||:.........|::.....      |:|.||.|:.
  Rat   427 SPATSAGP-EQLTGLPRRPPG--------EPLQGFSKLGAGGLRSPGGG------RDCMVCFESE 476

  Fly   585 VTTALVPCGHNMFCMECANHICLSMDAVCPVCNSIVYHAMRI 626
            ||.||||||||:||||||..||...|..||||:.....|:||
  Rat   477 VTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRI 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11360	NP_651934.2	KH-I_MEX3_rpt1	123..195	CDD:411851	61/71 (86%)
		KH-I_MEX3_rpt2	231..302	CDD:411852	52/70 (74%)
		PEX10	<515..621	CDD:227861	40/105 (38%)
		RING-HC_MEX3	575..627	CDD:438181	31/52 (60%)
Mex3a	NP_001385668.1	KH-I_MEX3_rpt1	132..204	CDD:411851	61/71 (86%)
		KH-I_MEX3_rpt2	221..292	CDD:411852	52/70 (74%)
		RING-HC_MEX3A	465..520	CDD:438380	31/60 (52%)