Protein Alignment CG11360 and Mex3d

DIOPT Version :10

• Sequence 1: NP_651934.2
• Gene: CG11360 / 43810
• FlyBaseID: FBgn0039920
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_001386628.1
• Gene: Mex3d / 299613
• RGDID: 1310576
• Length: 719
• Species: Rattus norvegicus
• Alignment Length: 644
• Identity: 235/644 - (36%)
• Similarity: 299/644 - (46%)
• Gaps: 147/644 - (22%)

  Fly    30 MSEQSKVNESTLPLSDDPRTLQLALELSLVGFNDNQNCYAQPAQPLPMPLSARSDFEIGTINSTL 94
            |:..|.|....|||.|                        ....|.|.|....:.|        .
  Rat   174 MAVASPVAPGGLPLLD------------------------PDVSPRPSPPDVFASF--------A 206

  Fly    95 PIPSA--PNCLLLPNAGAVSSEDRSKKSQNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYI 157
            |.|:|  |:.||......:.|.   |||.||||||||||||||||||||||||||||||||||||
  Rat   207 PHPAALGPSTLLAEQLNVIGSR---KKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYI 268

  Fly   158 KTPVRGEEPVFVVTGRKEDVNKAKREILSAADHFSLIRASRKPVSDSQNNGMVGSTTSSGGGAVP 222
            |||||||||||:||||||||..|||||||||:|||||||:|     |:..|:.|:|
  Rat   269 KTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSLIRATR-----SKAGGLSGAT--------- 319

  Fly   223 RMSGPPCMPGQVTIQVRVPYRVVGLVVGPKGATIKHIQQETQTYIVTPSREKEPIFEVTGLPDNV 287
              .|||.:|||.|||||||||||||||||||||||.|||.|.||||||.|:|||:|.|||:|:||
  Rat   320 --PGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENV 382

  Fly   288 DTARKQIEAHIALRTGSGSGSGDAITMQSSDSVDTKEY----ASL-----------PSLTQILND 337
            |.||::|||||.||||:.:.:|......::.:....:.    |||           |:.|..|..
  Rat   383 DRAREEIEAHITLRTGAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKAPHPGRRPPTATGGLRG 447

  Fly   338 DLNSEILSSIYKNSVPSTQEYANNSMKTVVNVSNSVKL-------------VQGHHTG-----NC 384
            |      :::...|.|......:.....:.:.|.|...             ..|..||     :|
  Rat   448 D------NALGAASTPEPFYVGSRGGPALPDPSPSSPYGGSGNGGFTFGGDGPGAPTGTTTPEDC 506

  Fly   385 FQKSEFAEMEMTANITAADILDKRLPGNEVSVPLAKANVANIVFRTTSSKTLSFCPPTSTSASFH 449
            ....:|..:::|...||.           :..|..:|         ......|.||..:.:.:
  Rat   507 DFGFDFLALDLTVPATAT-----------IWAPFERA---------APLPAFSGCPTVNGAPA-- 549

  Fly   450 SNCNANILTRSCSSASSTTSTKSTNNSANTP-PEILNIWKSISDSIDVDEGIGDSPSIWNQPANI 513
               ..|..||..|......:|  ..:|...| |..|::...::.. .|.:.:|..|  |..|.:.
  Rat   550 ---QPNTGTRRSSGGGGAATT--PRHSPTLPEPGGLSLELPLARR-GVPDPVGAVP--WRPPQST 606

  Fly   514 IPTAHCSPTISISPT-----------DSLLGMGEHSANQQNLNHAKEPIMPNLPQKIKGIQVQSN 567
            :|....|.|.|.:|:           |::...|.|..:....|.:.....|..|.....
  Rat   607 LPPFSGSTTFSTTPSLPSTTPASSTMDTVPSEGNHKPSTTAANSSASAAAPGPPAAALA------ 665

  Fly   568 ADNFLTHRECFVCNENTVTTALVPCGHNMFCMECANHICLSMDAVCPVCNSIVYHAMRI 626
                   |||.||:|.....||||||||:|||:||..||...:..||.|.:....|:.|
  Rat   666 -------RECVVCSEGEAMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIHI 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11360	NP_651934.2	KH-I_MEX3_rpt1	123..195	CDD:411851	67/71 (94%)
		KH-I_MEX3_rpt2	231..302	CDD:411852	56/70 (80%)
		PEX10	<515..621	CDD:227861	35/116 (30%)
		RING-HC_MEX3	575..627	CDD:438181	26/52 (50%)
Mex3d	NP_001386628.1	PHA03247	<27..215	CDD:223021	14/72 (19%)
		KH-I_MEX3_rpt1	234..306	CDD:411851	67/71 (94%)
		KH-I_MEX3_rpt2	326..397	CDD:411852	56/70 (80%)
		PHA03247	<431..643	CDD:223021	43/247 (17%)
		RING-HC_MEX3	666..718	CDD:438181	26/52 (50%)