Protein Alignment Ekar and GLR2.4

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_001328410.1
• Gene: GLR2.4 / 829299
• AraportID: AT4G31710
• Length: 912
• Species: Arabidopsis thaliana
• Alignment Length: 966
• Identity: 199/966 - (20%)
• Similarity: 352/966 - (36%)
• Gaps: 227/966 - (23%)

  Fly     7 FLLFQF-LSYGLG---VPPLVRIGAIFSNQPGMYNSELAFRYAIHRLNMDKSLLPETTVDYYVEY 67
            ||:|.| :..|.|   ...::.:|.:  ...|...|.|:.......|:...|..||:.....:.:
plant    35 FLVFIFGVKLGKGQNTTIQVINVGVV--TDVGTTASNLSLLAINMSLSDFYSSRPESRTRLLLNF 97

  Fly    68 V-NRFDSFETVQKVCKLIR-VGVQAVFSPTDSVLATHINSICDALDIPNI-----------GRSA 119
            . :|.|..........||: ..|:|:..|..::.|:.:..:.....:|.|           |||.
plant    98 ADSRDDVVGAAAAALDLIKNKEVKAILGPRTTMQASFVIEVGQKSQVPIISFSATSPFLDSGRSP 162

  Fly   120 HDFSINVYPSKQLVNYAFNDVIQYLNWTRFGILHEKENGIINLHQLSRSFHGEVHMRQVSRDSYV 184
            :.|......|.|:  .|.:::|:...|.....::|           :.:| ||..|     ....
plant   163 YFFRSTYDDSSQV--QAISEIIKVFGWREVVPVYE-----------NNAF-GEGIM-----PGLT 208

  Fly   185 SALNEFKGKEIHNIIIDTNS--NGISI-LLK------NILQQQMNEYKYHYLFTSFDLETYDLED 240
            .||.....:..:..:|..|:  :.||: |||      .:....||.:....:|:.........:.
plant   209 DALQAINIRIPYRTVISPNATDDEISVDLLKLMTKPTRVFVVHMNRFLASRVFSKARETGLMKQG 273

  Fly   241 FKYNFVN--ITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYLNLHIKKSTILESEPALMFDSVY 303
            :.:...|  |....|::..|:...|.:  ||:.:|....:   .|...:|.:.::.|
plant   274 YAWILTNGVIDHLVLMNGTDIEAMQGV--IGIRTHFPISE---ELQTFRSRLAKAFP-------- 325

  Fly   304 VFAIGLQTLEQSHSLTLLNISCEEE-------NSWDG--------------GLSLINYLNAVEWK 347
            |..:.:..|....:.|.|.::.||.       :..||              |..||..|:.:::|
plant   326 VSELNIYGLRAYDATTALAMAVEEAGTTNLTFSKMDGRNISDLEALSVSEYGPKLIRSLSQIQFK 390

  Fly   348 GLTGPIQFKDGQRVQFKLDLIKLKQHSIVKVGEWTP---------------------HGHLNITE 391
            ||:|...|.|||......:::.:.....:.||.||.                     ..|||
plant   391 GLSGDYHFVDGQLHASVFEIVNVIDGGGILVGFWTQDKGLVKDLSPSSGTTRTFSSWKNHLN--- 452

  Fly   392 PSMFFDAGSMNVTLVVITILETPYVMMHYGKN--------------------FTGNERFYGFCVD 436
            |.::     ..:||.|....|.|    ..||.                    .|......|||:|
plant   453 PILW-----PGITLTVPKGWEIP----TNGKELQIGVPVGTFPQFVKVTTDPLTHETIVTGFCID 508

  Fly   437 ILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFT 501
            ..|.:.:.:.:|.....:|   :|..|.:|.:                   .||...|.|.:|||
plant   509 FFEAVIQAMPYDVSHRFIP---FGDDDGKTND-------------------TTILANRSSYVDFT 551

  Fly   502 KPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINAC 566
            .|:...|:.::..:..:.......|..||...:|...|.::|:|...::|      :|.: :|:
plant   552 LPYTTSGVGMVVPLKDNVARSSLIFFKPLTPGLWGMTLGSFFVVGFVVWI------LEHR-VNS- 608

  Fly   567 DLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLT 631
               ..:...|:.::..|||.. :.|..:|.....:.:.|::..||.|..|::..||||:|::.||
plant   609 ---EFTGPPQYQISTMFWFAF-SIMVFAPRERVMSFTARVVVITWYFIVLVLTQSYTASLSSLLT 669

  Fly   632 TERMINPIENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFT------- 689
            |:: :||.|        |.|. ..|..|..:.:.|||.:         :...:.|.|.
plant   670 TQQ-LNPTE--------TSIK-NVLAKGGPVAYQRDSFV---------LGKLRESGFPESRLVPF 715

  Fly   690 TTYEDGIKRVNQG------NYAFLMESTMLDYIVQRDCNLTQIGGL-LDTKGYGIATPKGSPWRD 747
            |:.|...:.:|:|      :.|| ||...:...:.:.|...::..: .|..|:|...|.|||...
plant   716 TSPEKCEELLNKGPSKGGVSAAF-MEVPYVRVFLGQYCKKYKMVEVPFDVDGFGFVFPIGSPLVA 779

  Fly   748 KISLAILELQERGDIQMLYDKWWKNTDETC----TRKNTSKQSKANSLGLESIGGVFVVLIAGII 808
            .:|.|||::.|......|...|:||.|:||    ...:.:.......|.|:|    |::|.....
plant   780 DVSRAILKVAESNKATQLETAWFKNIDKTCPDPMNNPDPNPTVSFRKLSLDS----FLLLFVAAA 840

  Fly   809 VAAVVAFFEFWYNFRYNYEATPSQSVVNNKYNQDGILESERNYTPPDRSFWIEIAE 864
            ....:|..:|...|           ::.|:.    ||..|.......:..|::..|
plant   841 TVCTLALLKFVICF-----------LIQNRI----ILNDEFYRGKRMKEMWLKFME 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	82/431 (19%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	91/402 (23%)
		Lig_chan	532..806	CDD:459656	71/291 (24%)
GLR2.4	NP_001328410.1	PBP1_GABAb_receptor_plant	56..434	CDD:380645	79/411 (19%)
		GluR_Plant	474..802	CDD:270404	84/381 (22%)
		Periplasmic_Binding_Protein_Type_2	482..>696	CDD:473866	57/257 (22%)