Protein Alignment Ekar and GLR1.4

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_187408.2
• Gene: GLR1.4 / 819940
• AraportID: AT3G07520
• Length: 861
• Species: Arabidopsis thaliana
• Alignment Length: 942
• Identity: 182/942 - (19%)
• Similarity: 349/942 - (37%)
• Gaps: 276/942 - (29%)

  Fly    69 NRFDSFETVQKVCKLIRVGVQAVFSPTDSVLATHINSICDALDIPNIGRSAHDFSINVYPSKQLV 133
            |:.|:.:.:..|.:.:|:|:.......:..|.|  .||..||.         ||
plant    31 NQKDNVDRLPVVYEDVRIGLVVDMGSMEGKLVT--TSISMALS---------DF----------- 73

  Fly   134 NYAFNDVIQYLNWTRFGILHEKENGIINLHQLSRSFHGEVHMRQVSRDSYVSALNEFKGKEIHNI 198
             |..|:..:    ||..:             |||..||:      ...:..:|::..:.:::..:
plant    74 -YHVNNGYR----TRVSV-------------LSRDSHGD------PLQALAAAMDLLQTEQVEAL 114

  Fly   199 IIDTNSNGISIL-LKNILQ----------------QQMNEYKYHY-----------------LFT 229
            :     .|.|:| .||:.:                ..::..||:|                 ||:
plant   115 V-----GGQSLLEAKNLAELGEKTKVPVISSFQVPSSLSLAKYNYFIQATHDTSSEAKGIAALFS 174

  Fly   230 SFDLET----YDLED------------FKYNFVNI---TSFRLVDTADVGVKQILK----DIGLY 271
            :||..|    |:.:|            |:.|.::|   ..|.:....:..:||:.|    .|.::
plant   175 NFDWRTAVLIYEDDDDWRESIQPLVGHFQQNAIHIEYKAEFSVSSNEECIMKQLRKFKASGIRIF 239

  Fly   272 SHHIFKKPYLNL------------------------HIKKSTILESEPALMFDSVYVFAIGLQTL 312
            ..||.::....|                        :.:.:..|..|.   .:.|..|...:...
plant   240 VAHISERIANRLFPCARRLGMMEEGYAWILTARSMNNFQDTNYLAKEE---MEGVIGFKSYIPLT 301

  Fly   313 EQSHSLTL---LNISCEE-------------ENSWD----------GGLSLINYLNAV----EWK 347
            |:.|:.||   .::..||             :.:|.          .|||:.:.|.|:    :.|
plant   302 EELHNFTLRWKRSLRLEEVVTRMSVCSIWAHDIAWSLARAAEVAKLPGLSVYDLLEAIPESAKHK 366

  Fly   348 GLTGPIQFKDGQRVQFKLDLIKLKQHSIVKVGEWTP-------HGHLNITE--PSMFFDAGSMNV 403
            ||:|.|:|.|.:.:..|.:::.:.......||.|..       ...|:.|:  .::.:..||..:
plant   367 GLSGDIKFIDKKFISDKFEIVNMIGRGERSVGLWNSGSFISNRRRRLSSTKALETIIWPGGSTRI 431

  Fly   404 TLV------------VITILE-----TPYVMMHYGKNFTGNERFYGFCVDILETISREVGFDYIL 451
            ..:            .:.:|.     ||.::.......||.....|:|:|:.||  ..:.|:|.:
plant   432 PKIRSLKEKRHGKKKKLRVLVPAGNITPQILEVKTDFKTGVTAATGYCIDVFET--SILPFNYEV 494

  Fly   452 DLVPDRKYGAKDPETGEWNGMVAQL--MKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFK 514
            :.:|  ..||.:.:  .:|.:|..|  .|.|.|.|||.:|||..|...:|||.||.::|::::
plant   495 EYIP--WPGAINYK--NYNDLVYTLYSQKDKYDAAVGDITITDNRSLYVDFTLPFTDMGLAVV-- 553

  Fly   515 VPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSL 579
              |::...::....||.:.:|:.:...:.|....::::.:..       || |.:. |...|...
plant   554 --TAKDKSMWIIFKPLTLSLWLTIASFFILTGAIVWLIERHD-------NA-DFQG-SCFQQIGT 607

  Fly   580 TDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAED 644
            ...|.|:...|..:  :.....|| |.:...|.|..||:.::|||.|.:.:|.:::..
plant   608 LLCFGFSTLVFAHR--ERLQHNMS-RFVVIVWIFAVLILTSNYTATLTSVMTVQQIRG------- 662

  Fly   645 LASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTY------EDGIKRVNQGN 703
                       |.|...:.||..|:.       .::.|..|:.....|      :|....:..|.
plant   663 -----------LKSNENIGFFSASIA-------ANVVNDNPTFQGPRYKGLKTADDFTNALRNGT 709

  Fly   704 YAFLMEST--MLDYIVQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLY 766
            .:|:::..  :..::.:.......:.....|.|:|.|..||||...|:|..|.:|:....::.:
plant   710 ISFIVDEVPYVKLFVAKHPSEFVIVETESVTNGFGFAFQKGSPLVQKVSREIEKLRRTEKLKAI- 773

  Fly   767 DKWWKNTDETCTRKNTSKQSK--ANSLGLESIGGVFVVLIAGIIVA----------------AVV 813
            :.||      ..|:.||..|:  .:.|.:.:..|:|  :|.|:..|                .|:
plant   774 ENWW------FQRQTTSATSEDTFHPLTVYTFRGLF--MITGVSFAFALIVYLIPWNREQRQVVL 830

  Fly   814 AFFEFWYNFRYNYEATPSQSVVNNKYNQDGIL 845
            ..|..:.:.|:..|..||.: ..|:.|::.::
plant   831 KHFHRYVSHRFAREIRPSPT-TPNRQNENSVI 861

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	77/438 (18%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	83/395 (21%)
		Lig_chan	532..806	CDD:459656	55/283 (19%)
GLR1.4	NP_187408.2	PBP1_GABAb_receptor_plant	47..410	CDD:380645	73/416 (18%)
		GluR_Plant	448..778	CDD:270404	84/383 (22%)
		Periplasmic_Binding_Protein_Type_2	476..>657	CDD:473866	53/202 (26%)