Protein Alignment Ekar and GLR3.5

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_001324013.1
• Gene: GLR3.5 / 817800
• AraportID: AT2G32390
• Length: 953
• Species: Arabidopsis thaliana
• Alignment Length: 960
• Identity: 209/960 - (21%)
• Similarity: 372/960 - (38%)
• Gaps: 237/960 - (24%)

  Fly     3 IASGFLL------------------FQFLSYGLGVPPLVRIGAIFSNQPGMYNS------ELAFR 43
            ::.||:|                  |...|....:|..|.:||:|:     |:|      :|||.
plant    10 VSMGFMLLCISALWVLPIQGAGRESFSRNSSSSSLPSSVNVGALFT-----YDSFIGRAAKLAFV 69

  Fly    44 YAIHRLNMDKSLLPETTVDYYVEYVNRFDSFETVQKVCKLIRVGVQAVFSPTDSVLATHINSICD 108
            .||..:|.|:|:|..|.::...:..| ...|.......:|:...|.|...|..|.:...|:.:.:
plant    70 AAIEDINADQSILRGTKLNIVFQDTN-CSGFVGTMGALQLMENKVVAAIGPQSSGIGHIISHVAN 133

  Fly   109 ALDIPNIGRSAHDFSINVYPSKQLVNY---------------AFNDVIQYLNWTR-FGILHEKE- 156
            .|.:|.:..:|.|      |:...:.|               |..|.:.|..|.. ..|..:.|
plant   134 ELHVPFLSFAATD------PTLSSLQYPYFLRTTQNDYFQMNAITDFVSYFRWREVVAIFVDDEY 192

  Fly   157 --NGIINLHQLSRSFHGEVHMRQVSRDSYVSALNEFKGKEIHNIIIDTNSNGISILLKNILQQQM 219
              |||        |..|:...::.::.||.:|...           ..:::.||.||.::...:.
plant   193 GRNGI--------SVLGDALAKKRAKISYKAAFPP-----------GADNSSISDLLASVNLMES 238

  Fly   220 NEYKYHY-------LFTSFDLETYDLEDFKYNFVN----ITSFRLVDTADVGVKQILKDIGLYSH 273
            ..:..|.       :|:.  .::..:....|.::.    :|:...::..|.....:|:.:..:.|
plant   239 RIFVVHVNPDSGLNIFSV--AKSLGMMGSGYVWITTDWLLTALDSMEPLDPRALDLLQGVVAFRH 301

  Fly   274 HI--------FKKPYLNLHIKKSTILESEPAL------MFDSVYVFAIGLQT-LEQSHSLTLLNI 323
            :.        ||..:.||..|:|  |:|:...      .:|||::.|..|.. ..|.:::|..|
plant   302 YTPESDNKRQFKGRWKNLRFKES--LKSDDGFNSYALYAYDSVWLVARALDVFFSQGNTVTFSN- 363

  Fly   324 SCEEENSWDGGLSL------------INYLNAVEWKGLTGPIQF-KDGQRVQFKLDLIKLKQHSI 375
            .....|:.|.|:.|            :..:..:.:.||||.|:| .:..|:....|::.:|....
plant   364 DPSLRNTNDSGIKLSKLHIFNEGERFLQVILEMNYTGLTGQIEFNSEKNRINPAYDILNIKSTGP 428

  Fly   376 VKVGEWTPHGHLNITEPSMFFDAGS--------MNVTLVVITILETP--YVMMHYG--------- 421
            ::||.|:.|...::..|...:...|        :|..:....:::.|  :|....|
plant   429 LRVGYWSNHTGFSVAPPETLYSKPSNTSAKDQRLNEIIWPGEVIKPPRGWVFPENGKPLKIGVPN 493

  Fly   422 ----KNFTGNER----FYGFCVDILETISREVGFDYILDLVP---DRKY-----GAKDPETGEWN 470
                ||:...::    ..|||:||         |:..:.|:|   .|.|     |.|:|   .::
plant   494 RVSYKNYASKDKNPLGVKGFCIDI---------FEAAIQLLPYPVPRTYILYGDGKKNP---SYD 546

  Fly   471 GMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISIL--FKVPTSEPTRLFSFMNPLAIE 533
            .:::::.....|:|||.:||...|...:|||:||:..|:.::  .|...|.|   :||:.|..||
plant   547 NLISEVAANIFDVAVGDVTIITNRTKFVDFTQPFIESGLVVVAPVKGAKSSP---WSFLKPFTIE 608

  Fly   534 IWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQF------SLTDSFWFTIGTFMQ 592
            :|......:..|...|:|                ||: ....:|      .:...|||:..|...
plant   609 MWAVTGALFLFVGAVIWI----------------LEH-RFNEEFRGPPRRQIITVFWFSFSTMFF 656

  Fly   593 QSPDIYPRAMST--RIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGT 655
            ...:   ..:||  |.:...|.|..|||.:||||:|.:.||.:::.:.||..:.|.:..| ..|.
plant   657 SHRE---NTVSTLGRFVLLVWLFVVLIINSSYTASLTSILTVQQLTSRIEGMDTLIASNE-PIGV 717

  Fly   656 LDSGSTMTFFRDSVIETYKKIWRSMDNK---KPSAF-----TTTYEDGIKR-VNQGNYAFLMEST 711
            .|.    ||           .|:.:.|:   .||..     ...|...::| ...|..|.:::.
plant   718 QDG----TF-----------AWKFLVNELNIAPSRIIPLKDEEEYLSALQRGPRGGGVAAIVDE- 766

  Fly   712 MLDYI----VQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWKN 772
             |.||    ...:|....:|......|:|.|..:.||....:|.|||:|.|.|.::.:..| |..
plant   767 -LPYIKALLSNSNCKFRTVGQEFTRTGWGFAFQRDSPLAVDMSTAILQLAEEGKLEKIRKK-WLT 829

  Fly   773 TDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFF---EFW 819
            .|..||.:.:..::  ..:.::|..|:|  ||.|::....:..|   .||
plant   830 YDHECTMQISDTEN--YQISVQSFWGLF--LICGVVWFIALTLFCWKVFW 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	87/429 (20%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	100/418 (24%)
		Lig_chan	532..806	CDD:459656	71/294 (24%)
GLR3.5	NP_001324013.1	PBP1_GABAb_receptor_plant	49..444	CDD:380645	87/430 (20%)
		GluR_Plant	485..828	CDD:270404	96/396 (24%)