Protein Alignment Ekar and GLR2.9

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_001325277.1
• Gene: GLR2.9 / 817458
• AraportID: AT2G29100
• Length: 942
• Species: Arabidopsis thaliana
• Alignment Length: 1013
• Identity: 215/1013 - (21%)
• Similarity: 372/1013 - (36%)
• Gaps: 249/1013 - (24%)

  Fly     6 GFLLFQFLSYGLGVPPL--VRIGAIFSNQPGMYNSELAFRYAIHRLNMDKSLLPETTV-----DY 63
            ||||   :..|||....  :::|.:..                  ||...|.:..|::     |:
plant    16 GFLL---MGVGLGQNQTSEIKVGVVLD------------------LNTTFSKICLTSIKMAVSDF 59

  Fly    64 YVEYVNRF--------DSFE-TVQ---KVCKLIRV-GVQAVFSPTDSVLATHINSICDALDIPNI 115
            |.::.|..        ||.| |||   ....||:. .|.|:..|.:|:.|..:..:.:...:|.|
plant    60 YADHPNYLTRLTLHVRDSMEDTVQASAAALDLIKTEQVSAIIGPINSMQADFMIKLANKTQVPTI 124

  Fly   116 GRSAHDFSINVYPSKQLVNYAFND---------VIQYLNWTRFGILHEKENGIINLHQLSRSFHG 171
            ..||....:....|...|....:|         :.::..|.|...::           :...| |
plant   125 TFSATSPLLTSIKSPYFVRATIDDSSQVRAIASIFKFFRWRRVVAIY-----------VDNEF-G 177

  Fly   172 EVHMRQVSRDSYVSALNEFKGKEIHNIII--DTNSNGISILLKNILQQQMNEYKYHYLFTSFDLE 234
            |..|     .....||.:.   |:...:|  :...:.|...|:.::::|...:..| :.:|..|.
plant   178 EGFM-----PFLFDALQDV---EVKRSVIPPEAIDDEIQKELRKLMERQARVFVVH-MESSLALR 233

  Fly   235 TYDL--------EDFKYNFVN--------ITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYLNL 283
            .:.:        |.:.:...|        |.:.|.::|.: ||      :|:.||....|...:.
plant   234 VFQIARDIGMMEEGYVWLMTNGMTHMMRHINNGRSLNTIE-GV------LGVRSHVPKSKELGDF 291

  Fly   284 HIKKSTILESEPALMFDSVYVFAIGLQTLEQSHSLTLLNISCEEENS----WDGGL--------- 335
            .::.....|.|...|.|.:.|||     |....|:|.|..:.|:.|:    :|.|.
plant   292 RLRWKRTFEKENPSMRDDLNVFA-----LWAYDSITALAKAVEKANTKSLWYDNGSTLSKNRTDL 351

  Fly   336 ----------SLINYLNAVEWKGLTGPIQFKDGQRVQFKLDLIKLKQHSIVKVGEWTPH-GHLNI 389
                      ||....:.|.:.||.|..:..|||....|.::|....:....:|.|||. |.::.
plant   352 GNVGVSLYGPSLQKAFSEVRFNGLAGEFKLIDGQLQSPKFEIINFVGNEERIIGFWTPRDGLMDA 416

  Fly   390 TEPSM-----------------------------------FFDAGSMNVTLVVITILETPYVMMH 419
            |..:.                                   |||  .:.||:..||..:||
plant   417 TSSNKKTLGPVIWPGKSKIVPKGWEIPGKKLRVGVPMKKGFFD--FVKVTINPITNKKTP----- 474

  Fly   420 YGKNFTGNERFYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLA 484
                       .|:.::|.|...:|:.:     ||.......:.|  ..:|.:|.|:.....|..
plant   475 -----------TGYAIEIFEAALKELPY-----LVIPEYVSFESP--NNYNNLVYQVYDKTWDAV 521

  Fly   485 VGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCI 549
            ||.:|||..|....|||.||...|:|::..|..:|....:.|:.|.::|:|:.....:..:...:
plant   522 VGDITITANRSLYADFTLPFTESGVSMMVPVRDNENKDTWVFLEPWSLELWVTTGCFFVFIGFVV 586

  Fly   550 YIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGT--FMQQSPDIYPRAMSTRIISSTWG 612
            ::      .|.: :|. |...   ..|:.:..|.||:..|  |..:...:...|   |.:...|.
plant   587 WL------FEHR-VNT-DFRG---PPQYQIGTSLWFSFSTMVFAHRENVVSNLA---RFVVVVWC 637

  Fly   613 FFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTE-ISYGTLDSGSTMTFFRDSVIETYKKI 676
            |..|::..||||:|.:|||.:.:...:.|..||....: :.|   ..|:   |.:|.::    .:
plant   638 FVVLVLTQSYTASLTSFLTVQSLQPTVTNVNDLIKNRDCVGY---QGGA---FVKDILL----GL 692

  Fly   677 WRSMDNKKPSAFTTTYEDGI-KRVNQGNYAFLMESTMLDYIVQRDCN-LTQIGGLLDTKGYGIAT 739
            ....|..||.......:|.: |..::|..|...|...|..|:.:.|: ...:.....|.|:|.|.
plant   693 GFHEDQLKPFDSAKDADDLLSKGKSKGIAAAFDEVAYLKAILSQSCSKYVMVEPTFKTGGFGFAF 757

  Fly   740 PKGSPWRDKISLAILELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLI 804
            ||.||...:.|.|||.|.:....|.:.|:|:...:: |....|:..|  |.|.|.|..|:|  ||
plant   758 PKNSPLTGEFSRAILNLTQNNVTQQIEDRWFPKKND-CPDPMTALSS--NRLNLSSFLGLF--LI 817

  Fly   805 AGIIVA----AVVAFF--------------EFWYNFRYNYEATPSQSVVNNKYNQDGI--LESER 849
            ||..::    ..||.|              ..|...::.::....:.:.::.:....|  :.|..
plant   818 AGTAISFSLLVFVALFLYEHRHTLGDDSEDSLWRKLKFLFKIFDEKDMNSHTFKNSAIHNISSPM 882

  Fly   850 NYTPPDRSF-----WIEIAE-----ELRYASWCMNKQK 877
            .:..|..|.     |.:...     |||..|:..::::
plant   883 THKTPSPSTVQITPWPQSPSQNREFELRRVSFSPSEER 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	86/434 (20%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	92/373 (25%)
		Lig_chan	532..806	CDD:459656	69/278 (25%)
GLR2.9	NP_001325277.1	PBP1_GABAb_receptor_plant	33..415	CDD:380645	86/432 (20%)
		GluR_Plant	445..788	CDD:270404	94/391 (24%)
		Lig_chan	568..821	CDD:459656	71/281 (25%)