Protein Alignment Ekar and grik5l

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_001072565.1
• Gene: grik5l / 780020
• XenbaseID: XB-GENE-5860197
• Length: 479
• Species: Xenopus tropicalis
• Alignment Length: 459
• Identity: 175/459 - (38%)
• Similarity: 267/459 - (58%)
• Gaps: 35/459 - (7%)

  Fly   405 LVVITILETPYVMMHYGKNFTGNERFYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEW 469
            |.|.||:|.|:.|    |..:|.|   |||:|:|..:::.:||:|.:..|.|.:||||| :.|.|
 Frog    43 LTVTTIMEQPFSM----KTESGME---GFCIDLLSELAQSLGFNYTIKEVKDGRYGAKD-QDGNW 99

  Fly   470 NGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILF-KVPTSEPTRLFSFMNPLAIE 533
            ||||.::::.:|||||..:|||.|||..:.||||||..|||||. |...||.:.||.|:.|.:.|
 Frog   100 NGMVGEVLRKEADLAVAPLTITGARERELAFTKPFMQTGISILLRKDDVSENSYLFGFLTPFSKE 164

  Fly   534 IWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIY 598
            .||.:|:||.:.|||:::||:|||.||       .|..:..|.|:..:|.||.:|.|..|..:.:
 Frog   165 TWIGILVAYVVTSLCLFLVGRLSPCEW-------TELSTEQNNFNFLNSLWFGVGAFTLQGAEPH 222

  Fly   599 PRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERM-INPIENAEDLASQTEISYGTLDSGSTM 662
            |:::|.|||:..|..||:::||:|.|:.||||.::.| ...|:..|||.:|..:.:||::|.||.
 Frog   223 PKSVSARIIAVIWWIFSIVLVAAYIASFAAFLNSDSMQTTNIQTFEDLVNQRTLEFGTINSSSTF 287

  Fly   663 TFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRVNQGNYAFLMESTMLDYIVQRDCNLTQIG 727
            .||::|...||:.|:..||.:|......::.:|::||.:.|||||.||.|.|.:|.:.|:|.:..
 Frog   288 QFFKNSKNPTYRMIYEYMDKRKDELLVKSFAEGVRRVKESNYAFLGESVMQDIMVAKHCDLVRAP 352

  Fly   728 GLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKANSLG 792
            .::..:|||||....||....:|:||||..|.|:|:.|..|||   |.||   |..:.:..|.:.
 Frog   353 QIIAGRGYGIAASLDSPLIKPLSVAILEQTESGNIEYLRKKWW---DNTC---NMKRSAGWNPVQ 411

  Fly   793 LESIGGVFVVLIAGIIVAAVVAFFEFWYNFRYN-----------YEATPSQSVVNNKYNQDGILE 846
            ..::||:|::|..|:.:..:.|..|.....|.|           :.....:.:..||.|| |..:
 Frog   412 PHTLGGIFLILGIGLALGVIAALVELVLKARNNADQQKKSCCSAFSEEMGERLGTNKENQ-GASD 475

  Fly   847 SERN 850
            |.::
 Frog   476 SAKS 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605
		PBP2_iGluR_Kainate	402..771	CDD:270432	154/367 (42%)
		Lig_chan	532..806	CDD:459656	104/274 (38%)
grik5l	NP_001072565.1	PBP2_iGluR_non_NMDA_like	41..396	CDD:270403	155/370 (42%)