Protein Alignment Ekar and Ir7e

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 696
• Identity: 133/696 - (19%)
• Similarity: 225/696 - (32%)
• Gaps: 226/696 - (32%)

  Fly   236 YDLEDFKYNFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYLNLHIKKSTILESEPALMFD 300
            |||...:.|.:|....|.|                            ||:....||...|:|:
  Fly    11 YDLSGEQMNHINEFVARAV----------------------------LHVVHHYILSVTPSLV-- 45

  Fly   301 SVYVFAIGLQTLEQSHSLTLL---NISCEEEN--------SWD-GGLSLINYLNAVEWKGLTGPI 353
                             |||.   |.:|...|        .|. ..|.::|.|..|.|..:.|..
  Fly    46 -----------------LTLCCRSNHTCNFYNKMMSTLFREWGLAPLQIVNVLRGVPWHPVPGRR 93

  Fly   354 QFKDGQRVQF-----KLDLIKLKQHSIVKVGEWTPHGHLNITEPSMFFDA------GSMNVTLVV 407
            .|    .|.|     ..:.|:::.:|    .|:..:.|..|     |..|      |.|.:
  Fly    94 HF----NVIFTDSFAAFEEIRMEYYS----REYNYNEHYFI-----FLQARDRLLQGEMRL---- 141

  Fly   408 ITILE--TPYVMMHYG---KNFTGNERFYGF-------CVDI-LETISREVGFDYI-LDLVPDRK 458
              |.:  ..|.::|..   :...|:..||.:       |.|: .:.|:|..|...: .||.| ||
  Fly   142 --IFDYCWRYRLIHCSIQVQKSNGDILFYSYYPFGEHGCSDMEPQLINRYNGSMLVEPDLFP-RK 203

  Fly   459 ----YGA----------------KDPE-----TGEWNG----MVAQLMKY--------------- 479
                :|.                :|.|     .|.:.|    .:|:.|.:
  Fly   204 LRNFFGCPLRCALWDVPPFLTLDEDQEEVLRVNGGYEGRLLLALAEKMNFTIAVRKVHVNMRDEA 268

  Fly   480 -------KADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSF---MNPLAIEI 534
                   :.||.:|.:..|.||..|...:..:..  ...:|.|..|. ..|.||   ..|..::|
  Fly   269 LEMLRRDEVDLTLGGIRQTVARGMVATSSHNYHQ--TREVFGVLASS-YELSSFDILFYPYRLQI 330

  Fly   535 WIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDI-Y 598
            |:.:|....|.:|...|||::.                   :..:...||..:.......|.: .
  Fly   331 WMGILGVVALSALIQLIVGRML-------------------RERMGSRFWLNLELVFVGMPLLEC 376

  Fly   599 PRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQ------TEISYGTLD 657
            ||:.:.|:.......::|||...|...|...:.|.::....:..|.|..:      |.|....||
  Fly   377 PRSHTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTIESLVQKNFTVVLTPIVQEVLD 441

  Fly   658 SGSTMTFFRDSVIETYKKI---------WRSMDNKKPSA------FTTTYEDGI-KRVNQGNYAF 706
            ...::...|..::|...::         .:...:...||      |.....|.: :|..||:.|.
  Fly   442 EIPSVQHMRFRLLEANSELDPLYFLEANHQLRQHVTASALDIFIHFNRLSADKVHQRGEQGSGAH 506

  Fly   707 LMESTMLDYIVQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWK 771
            .       .||..|....|:...|....:.|         |:::..|:.::..| :..::.:|
  Fly   507 F-------EIVPEDIISMQLTMYLAKHSFLI---------DQLNEEIMWMRSVG-LLSVWSRW-- 552

  Fly   772 NTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFE 817
            ...|:..|...|.|    .||...:..:|::::.|:||..:|...|
  Fly   553 ELSESYLRNEQSFQ----VLGTMELYAIFLMVLVGLIVGLLVFILE 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	33/170 (19%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	83/459 (18%)
		Lig_chan	532..806	CDD:459656	53/296 (18%)
Ir7e	NP_001138176.1	Periplasmic_Binding_Protein_Type_2	218..>313	CDD:473866	15/96 (16%)