Protein Alignment Ekar and grid1b

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_009304811.1
• Gene: grid1b / 557511
• ZFINID: ZDB-GENE-121214-84
• Length: 1048
• Species: Danio rerio
• Alignment Length: 930
• Identity: 266/930 - (28%)
• Similarity: 450/930 - (48%)
• Gaps: 143/930 - (15%)

  Fly     8 LLFQFLSYGL------GVPPLVRIGAIFSNQPGMYNSELAFRYAIHRLNMDKSLLPETTVDYYVE 66
            ||...||:|:      |...::.|||||.....  ..:..|:.||..|:::..:|....:.:.::
Zfish     3 LLIICLSFGILQCSSAGADSIIHIGAIFEENAA--RDDEVFQLAISDLSLNDDILQSEKITHSIK 65

  Fly    67 YVNRFDSFETVQKVCKLIRVGVQAVFSPTDSVLATHINSICDALDIPNI-------GRSAHDFSI 124
            |:...:.|:.||:.|:|:..|:.|:.:.|....|:.:.|:.||:.||::       |.......:
Zfish    66 YIEPNNPFQAVQEACELMTQGILALVTSTGCASASALQSLTDAMHIPHLYVQRNAEGSPRTACQL 130

  Fly   125 NVYPSKQLVNYA------FNDV----IQYLNWTRFGILHEKENGIINLHQLSRSFHGEVHMRQVS 179
            |..|..:....|      ..||    :..|.|.:|.:.::.:..|..|         :|.:.|.|
Zfish   131 NPSPDGERYTLAARPPVRLGDVMLTLVGELRWQKFIVFYDSDYDIRGL---------QVFLDQTS 186

  Fly   180 RDSYVSALNEFKGKEIHNIIIDTNSNGI-SILLKNILQQQMNEY-------------KYHYLFTS 230
            |          :|.::....:|.|.:|: |.|..::..:::|.|             :...:|..
Zfish   187 R----------QGLDVSLQRVDRNISGVFSSLFTSMRTEELNRYRDTLRRAILLLSPRGAQVFIH 241

  Fly   231 FDLET-YDLEDFKYNFVN--ITSFRLVDTA--DVG----VKQIL---KDIGL----YSHHIF--- 276
            ..:|| ...:|..:.|||  |:...:::.|  .:|    |:||.   :|..:    .||.|.
Zfish   242 QAVETNLASKDSHWVFVNEEISDTEILELAHSSLGRMTVVRQIFPLWRDSSVSCMRNSHRISSLL 306

  Fly   277 ---KKPYLNLHIKKSTILESEPALMFDSVYVFAIGL-QTLEQS--HSLTLLNISCEEENSWDGGL 335
               ::.||.       .||.....::|||.:.|... :.||..  ||:..||...:....|:||.
Zfish   307 CDPQEGYLQ-------SLEVSNLYLYDSVLMLANAFYRKLEDRKWHSMASLNCIRKSTKPWNGGW 364

  Fly   336 SLINYLNAVEWKGLTGPIQFKD---GQRVQFKL---DLIKLKQHSIVKVGEW-TPHGHLNITEPS 393
            |::..:......||||.:.|.:   ...|||::   ...:.....|.::..| :.|| ||.:...
Zfish   365 SMLETIQKGRITGLTGIMDFMENGSNSHVQFEILGTSFSETFGKDIKRLATWDSVHG-LNGSLKE 428

  Fly   394 MFFDAGSMNVTLVVITILETPYVMMHYGKNFTGN-ERFYGFCVDILETISREVGFDYILDLVPDR 457
            ...:.|...||:.|:|:||.|:||:  .:|..|. :|:.||.:|:||.:::.:||.|.:..|.|.
Zfish   429 SRIENGMQGVTVKVVTLLEDPFVMV--AENILGQPKRYKGFSIDVLEALAKILGFKYDIYQVADS 491

  Fly   458 KYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTR 522
            |||:: ...|.||||:.:|:..:|||||.::|||..||:|:||:|.:|:..:.||.:.| .|...
Zfish   492 KYGSQ-LSNGSWNGMIGELINKRADLAVSAITITPERENVVDFSKRYMDYSVGILHRKP-EEKIN 554

  Fly   523 LFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWK----CINACDLENISIGNQFSLTDSF 583
            :||...|..:.:|..:..|..:|.:.|:::.::..:..:    ..:|..:.|       ||..:.
Zfish   555 IFSLFAPFDLAVWACIAAAIPVVGVLIFLLTRMQMLRSQNPPGAHHASSMSN-------SLHSAI 612

  Fly   584 WFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQ 648
            |...|.|:||..|....:::.||:..:|..|:||:.:|||||||||||..||.|.|...:|||.|
Zfish   613 WIVYGAFVQQGGDSVVGSVALRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNTIRTFQDLARQ 677

  Fly   649 TEISYGTLDSGSTMTFFR---------DSVIETYKKIWRSMDNKKPSAFT-TTYEDGIKRVNQGN 703
            .:.:|||:...:...:|:         ||   ||.::||::.......|: ::..:||::..:|.
Zfish   678 MDFAYGTVRDSAVYDYFKAKGTNPLEQDS---TYAELWRTISKNNGQDFSVSSPSEGIRKAKKGP 739

  Fly   704 YAFLMESTMLDY--IVQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLY 766
            ||||.:..:::|  :...||.:|..|..:.:||||||...|||:||.||..||||||:||:.:|.
Zfish   740 YAFLWDMAVVEYAALTDDDCTITVSGNSMSSKGYGIAMQHGSPYRDLISQKILELQEKGDLDVLK 804

  Fly   767 DKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFWYNFRYNYEATPS 831
            .|||..|.......:::.|....||.|.|..|||.:|.||:::|.:||..|.|:|
Zfish   805 QKWWPRTGRCDLNSHSNAQPDGRSLKLHSFAGVFCILAAGLLLACLVAALEMWWN---------- 859

  Fly   832 QSVVNNKYNQDGILESERNY 851
                :|:..|:...|..::|
Zfish   860 ----SNRCRQEQPKEVTKDY 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	97/428 (23%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	139/385 (36%)
		Lig_chan	532..806	CDD:459656	97/289 (34%)
grid1b	XP_009304811.1	PBP1_iGluR_delta_1	25..426	CDD:380615	97/429 (23%)
		Periplasmic_Binding_Protein_Type_2	437..809	CDD:473866	139/385 (36%)