Protein Alignment Ekar and LOC4576285

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_061502502.1
• Gene: LOC4576285 / 4576285
• VectorBaseID: AGAMI1_009844
• Length: 456
• Species: Anopheles gambiae
• Alignment Length: 575
• Identity: 122/575 - (21%)
• Similarity: 228/575 - (39%)
• Gaps: 190/575 - (33%)

  Fly    72 DSFETVQKVCKLIRVGV------QAVFSPTDSVLATHINSICDALDIPNIGRSAHDFSINVYPSK 130
            |||:|:.......::..      :.|.:|:...|                     ||:|::.|.
Mosquito     8 DSFDTLHPYSNTFQMPFVTPWFPEKVLTPSSGFL---------------------DFAISMRPD- 50

  Fly   131 QLVNY-AFNDVIQYLNWTRFGILHEKENGIINLHQL-------SRSFHGEVHMRQVSRDS----- 182
               :| |..|.::|..|.|...:::..:|::.|.|:       :.:||.|. :::::..|
Mosquito    51 ---HYQAIIDTVRYYGWDRIIYMYDSHDGLLRLQQIYQGLRPGNETFHVET-VKRIANVSDAIEF 111

  Fly   183 --YVSALNEFKGKEIHNIIIDTNSN-GISILLKNILQQQMNEYKYHYLFTSFDL-ETYDLEDFKY 243
              .:..||.:..|   :|::|.::. ...|::.::....:.:..||||.:...: :.::.|..:|
Mosquito   112 LRTIEELNRWSRK---HIVLDCSTELAKDIVVSHVRDITLGKRTYHYLLSGLVMDDRWESEVIEY 173

  Fly   244 NFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKK--PYLNLHIKKSTILESEPALMFDSVYVFA 306
            ..:|||.||:|||:...||:.|..        :|:  |..:....|. ::.::.|||:|:|:|..
Mosquito   174 GAINITGFRIVDTSKKYVKEFLDG--------WKRLDPTTSQGAGKE-LISAQAALMYDAVFVLV 229

  Fly   307 IGLQTL-----EQSHSLTLLN--------------ISCEEENS----WDGGLSLINYLNAVEWKG 348
            .....:     :|..:.|:.|              :.|.....    |:.|..:..||..||..|
Mosquito   230 EAFSKIMRKKPDQFRAYTMRNRGQPFNLPANGTRTLDCNTSKGWVTPWEHGDKISRYLRKVEISG 294

  Fly   349 LTGPIQF-KDGQRVQFKLDLIKLKQHS-IVKVGEWTPHGHL-------NITEPSMFFDAGSMNVT 404
            |||.|:| :||:|..:.|.::::..:| :|||.||:..|.|       ...:..|.::   .|.|
Mosquito   295 LTGDIRFNEDGKRQNYTLHVVEMTVNSAMVKVAEWSDEGGLAPVVAKYTRLKTDMHYE---RNKT 356

  Fly   405 LVVITILETPYVMMHY---GKNFTGNERFYGFCVDILETISREVGFDYILDLVPDRKYGAKDPET 466
            .:|.||:|.||:|:..   |:....||||.|:|.|:.|.:::::|.:     .|
Mosquito   357 YIVTTIIEEPYIMLRQPEPGETLETNERFEGYCKDLAELVAKKLGIN-----CP----------- 405

  Fly   467 GEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLA 531
                 ..:||.:.::                ||
Mosquito   406 -----RASQLRRCQS----------------ID-------------------------------- 417

  Fly   532 IEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISI----GNQFSLTDS 582
                            .:|||.:.||.||:.:|..|.:..::    .|:||...|
Mosquito   418 ----------------VLYIVSRFSPFEWRLVNYNDEQPDAVPQATANEFSALSS 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	84/374 (22%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	37/188 (20%)
		Lig_chan	532..806	CDD:459656	13/55 (24%)
LOC4576285	XP_061502502.1	None