Protein Alignment Ekar and Ir68b

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Alignment Length: 674
• Identity: 119/674 - (17%)
• Similarity: 209/674 - (31%)
• Gaps: 210/674 - (31%)

  Fly   232 DLETYDLEDFKYNFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYLNLHIKKSTILESEPA 296
            ::|.::||.|:.  .:..|...:..|:.|...:.:.:.:.:.|..:|     |:.|
  Fly    72 NMEAHELEPFRR--TDSLSIFQIPAAEKGDSLVRRILDMLNPHQRRK-----HMHK--------- 120

  Fly   297 LMFDSVYVFA---IG----LQTLEQSHSLTL---LNISCEEENSWD------GGLSLINYLN--- 342
                  |:|.   .|    |:....|.:..|   |.|:..|..::|      |||.:|..|:
  Fly   121 ------YLFVWPNAGRHQLLRLFRGSWAKKLLYGLAITGRENGTFDFDPFAWGGLQVIQRLDGEV 179

  Fly   343 --AVEWKGLTG-PIQFKDGQRVQFKLDLIKLKQHSIVKVGEWTPHGHLNITEPSMFFDAGSMNVT 404
              |.:.|.|.| |::|.     .|...|:.:.:..:...|.....|........|.    :.:||
  Fly   180 PYARKVKDLRGYPLRFS-----MFTDPLMAMPRSPVETAGYQAVDGVAARVVGEML----NASVT 235

  Fly   405 LVVITILETPYVMMHYGKNFTGNERFYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEW 469
            .|                 |..:...||.|:                             ..|.:
  Fly   236 YV-----------------FPEDNESYGRCL-----------------------------PNGNY 254

  Fly   470 NGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEI 534
            .|:|:.::......|..|..:.......::...|:....:.::......:|..|. |:......:
  Fly   255 TGVVSDIVGGHTHFAPNSRFVLDCIWPAVEVLYPYTRRNLHLVVPASAIQPEYLI-FVRVFRRTV 318

  Fly   535 WIYVLIAYFLVSLCIYIVGKLS-PIEWKCINACDLENISIGNQFSLTDSFWFTI-----GTFMQQ 593
            |..:|:...:|.|..:::.:|. .|..:.:           .||..|   |:.|     .|.:.:
  Fly   319 WYLLLVTLLVVVLVFWVMQRLQRRIPRRGV-----------IQFQAT---WYEILEMFGKTHVGE 369

  Fly   594 SPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDL------------- 645
            .........|.|.....|..||.::...|.|.|.:..........::..:||
  Fly   370 PAGRLSSFSSMRTFLMGWILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDLVHLDVHIYAVTTM 434

  Fly   646 -----ASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRVNQGNYA 705
                 ::.||..||.|::.|                     .:.|....|:|...:.|......|
  Fly   435 YDAVRSALTEHQYGLLENRS---------------------RQLPLGIATSYYQPVVRRRDRRAA 478

  Fly   706 FLMESTMLDYIVQRDCNLTQIGGLLDTKGYGIA------------TPKGSPWRDKISLAILELQE 758
            |:|.    |:.. ||..........:...|.||            .|:|||:     |..||...
  Fly   479 FIMR----DFHA-RDFLAITYDSQAERPAYHIAREYLRSMICTYILPRGSPF-----LHRLESLY 533

  Fly   759 RGDIQMLYDKWWKNTDETCTR---------------KNTSKQSKANSLG---------LESIGGV 799
            .|.::..:.:.|:..| ..||               ..|...|.:|.|.         |:.:.|.
  Fly   534 SGFLEHGFFEHWRQMD-LITRVGASPDAEEFLEDLGDQTDTDSGSNELAIRNKKVVLTLDILQGA 597

  Fly   800 FVVLIAGIIVA----AVVAFFEFW 819
            |.:...||.::    ||.....||
  Fly   598 FYLWSVGIGISCLGFAVEHAHWFW 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	36/179 (20%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	65/404 (16%)
		Lig_chan	532..806	CDD:459656	60/333 (18%)
Ir68b	NP_648548.1	None