Protein Alignment Ekar and Ir64a

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Alignment Length: 658
• Identity: 116/658 - (17%)
• Similarity: 203/658 - (30%)
• Gaps: 202/658 - (30%)

  Fly   341 LNAVEWKGLTGPIQFKDGQRVQFKLDLIKLKQ------HSIVKVGEWTP----HGHLNITEPSMF 395
            :.|.:.:.|.....|..|..:....:|...|:      :::..|  |.|    .||:|:||...|
  Fly   221 IQATDDEDLPSIESFLGGMNLYMNTELTLAKRMSEAAHYTLFDV--WNPGLNYGGHVNLTEIGSF 283

  Fly   396 FDAGSMNV----------------------TLVVITILETPYVMMHYGKNFTGNERFY------- 431
            .....:.:                      .:||:|           .||.||...:|
  Fly   284 TPTEGIQLHTWFRTTSTVRRRMDMQHARVRCMVVVT-----------NKNMTGTLMYYLTHTMSG 337

  Fly   432 ------GFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTI 490
                  .|..::|..:.....:.::|.......|    .:.|.::||:..|::.:.|  :|...|
  Fly   338 HIDTMNRFNFNLLMAVRDMFNWTFVLSRTTSWGY----VKNGRFDGMIGALIRNETD--IGGAPI 396

  Fly   491 TY--ARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVG 553
            .|  .|...||......:.....:|:.|.|.......|:.|...::||.::....|.   ::|:.
  Fly   397 FYWLERHKWIDVAGRSWSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWILIVGCGVLT---VFILW 458

  Fly   554 KLSPIEWKC------------------------------------INAC---------------- 566
            .|:.||||.                                    |.|.
  Fly   459 FLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEY 523

  Fly   567 -DLENISIGNQFS--------------------------LTDSFWFTIGTFMQQSPDIYPRAMST 604
             |...|..|..:.                          ..:|..|.:|...||........:|.
  Fly   524 EDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSG 588

  Fly   605 RIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFF---R 666
            |.|..|...||..|...|:|::...|..|:. ..|:...||. .:.:..|..|......:|   :
  Fly   589 RCIVITSLLFSFCIYQFYSASIVGTLLMEKP-KTIKTLSDLV-HSSLKVGMEDILYNRDYFLHTK 651

  Fly   667 DSV-IETYKKIWRSMDNKK-----------PSAFTT----TYEDGIKRVNQG------------- 702
            |.| :|.|.|...|:...|           |:..:|    :|.|.:.....|
  Fly   652 DPVSMELYAKKITSVPTTKENEADEDEPVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLD 716

  Fly   703 ---------NYAFLMESTMLDYIV------QRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLA 752
                     .:||.::......|:      |..|:||::......|...| ..|.||.|..||..
  Fly   717 PETGLLRHLGFAFHVDVAAAYKIIAETFSEQDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYG 780

  Fly   753 ILELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFE 817
            :..:.|.| |...:...|.:....|.:|..:.....:   ::::....::|:....:..::...|
  Fly   781 LRRVTETG-ILTYHFNVWHSRKPPCVKKIETSDLHVD---MDTVSSALLILLFSYAITLMILGTE 841

  Fly   818 FWYNFRYN 825
            ..|:..:|
  Fly   842 ILYSKWHN 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	12/58 (21%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	94/531 (18%)
		Lig_chan	532..806	CDD:459656	70/399 (18%)
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	24/122 (20%)
		Lig_chan	563..828	CDD:459656	55/271 (20%)