Protein Alignment Ekar and Ir60a

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Alignment Length: 666
• Identity: 127/666 - (19%)
• Similarity: 227/666 - (34%)
• Gaps: 185/666 - (27%)

  Fly   299 FDSVYVFAIGLQTLEQSHSLTLL---NISCEEENSWDGGLSLI---------------------- 338
            |..::.|....:...::::|.|:   ::|...:...:|...||
  Fly    59 FAQIFFFRNPKERFTRAYNLMLVHAFHLSSPADQIQEGFSKLINEAVTNPGPPDREELFQMRVAS 123

  Fly   339 --NYLNAVEWKGLTGPIQFKDGQRVQF-KLDLIK-LKQHSIVKVGEWTPHGHLNITEPSMFFDAG 399
              |..|..|.|   |.:...|...:.. .:|.:| |.:..||::..|.|.....:    :|.:|.
  Fly   124 DYNITNGTEDK---GELILADNYVIVVDSVDRLKELMKKKIVEMRSWNPGARFLV----LFHNAT 181

  Fly   400 SMNVTLVVIT-----ILETPYV----------MMHYGKNFTGNERFYGFCVDILETISREVGFDY 449
            ..|..|.|.:     ::|..||          .|:|  |...|:.:......||..  :.||..:
  Fly   182 CRNRPLGVASNIFKDLMEMFYVHRVALLYANSTMNY--NLLVNDYYSNVNCRILNV--QSVGQCH 242

  Fly   450 ILDLVPDRKYGAKDPETGEWNGMV-AQLMKYKADLAVGSMTITYARESVIDFTKPFMN----LGI 509
            ...|.|:             |.:| |.:..|.:..:..:.|. :|..|:   :.||:.    ||:
  Fly   243 DGKLYPN-------------NAVVKASMQDYVSGFSPRNCTF-FACSSI---SAPFVEADCILGL 290

  Fly   510 SILFKVPTSEPTRLFSFM-NPLAIEIWIYVLIAYFLVSLC-IYIVGKL-SPIEWKCI------NA 565
            .:          |:..|| |.|..::          ...| :...|:: .|..|..:      |.
  Fly   291 EM----------RILGFMKNRLKFDV----------NQTCSLESRGEMDGPANWTGLLGKVQNNE 335

  Fly   566 CDLENISIGNQF---SLTDSFWFTIGTFMQQSPDIYPRAMSTR---------IISSTWGFFSLII 618
            ||   ...|..:   .:.|.||.: .|::|.:...|.:....|         ..:.||..|.||:
  Fly   336 CD---FVFGGYYPDNEVADHFWGS-DTYLQDAHTWYIKMADRRPAWQALVGIFEAYTWIGFILIL 396

  Fly   619 VASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNK 683
            :.|:     .|..|..||.|........|.|.|:  .|....::......:.||.:..:.::
  Fly   397 IISW-----LFWFTLVMILPEPKYYQQLSLTAIN--ALAVTISIAVQERPICETTRLFFMAL--- 451

  Fly   684 KPSAFTTTYEDGIKRVNQGNYAFLMESTMLD--YIVQRDCNLTQIGGLLDTKGYGIATPKGSPWR 746
                  |.|  |:..|  ..|...|.:|..|  |:.|.| .||::            ...|.|:.
  Fly   452 ------TLY--GLNVV--ATYTSKMIATFQDPGYLHQLD-ELTEV------------VAAGIPFG 493

  Fly   747 DKISLAILELQERGDIQMLYDKWWKNTDE--TCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIV 809
            ..        :|..|       |::|.|:  .....|.|.:....|..||::......:::..:.
  Fly   494 GH--------EESRD-------WFENDDDMWIFNGYNISPEFIPQSKNLEAVKWGQRCILSNRMY 543

  Fly   810 AAVVAFFEFWYNFRYNYEATPSQSVVNN----KYNQDGILESERNYTPPDRSFWIEIAEELRYAS 870
            .......:..|.|..|..::|.|.::..    .:..:.|:...|     |...:.:|..:.||.:
  Fly   544 TMQSPLADVIYAFPNNVFSSPVQMIMKAGFPFLFEMNSIIRLMR-----DVGIFQKIDADFRYNN 603

  Fly   871 WCMNK--QKRPALTRT 884
            ..:|:  :.||....|
  Fly   604 TYLNRINKMRPQFPET 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	21/119 (18%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	82/411 (20%)
		Lig_chan	532..806	CDD:459656	57/297 (19%)
Ir60a	NP_611901.1	None