Protein Alignment Ekar and LOC1273165

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_061503118.1
• Gene: LOC1273165 / 1273165
• VectorBaseID: AGAMI1_009742
• Length: 1024
• Species: Anopheles gambiae
• Alignment Length: 926
• Identity: 332/926 - (35%)
• Similarity: 508/926 - (54%)
• Gaps: 75/926 - (8%)

  Fly    23 VRIGAIFSNQPGMYNSELAFRYAIHRLNMDKSLLPETTVDYYVEYVNRFDSFETVQKVCKLIRVG 87
            ::||.:|.....  ::||||:||:..:|.:|.......::.....|...|.|:..:|:|:|::.|
Mosquito    51 IKIGGLFDGDTD--DAELAFQYAVEAVNNEKLSYSNYQLEAQAVQVKYGDQFDVSKKLCRLLKTG 113

  Fly    88 VQAVFSPTDSVLATHINSICDALDIPNIGRSAHDF----SINVYPSKQLVNYAFNDVIQYLNWTR 148
            |..:|.|:....|.|:.|:||..::|:|......:    ::|::|...::...|.|::....|..
Mosquito   114 VAGIFGPSSPKSALHVQSVCDEKEMPHIETRWDAYTKLPTLNLHPHPHIMGRVFLDLVVAFEWKD 178

  Fly   149 FGILHEKENGIINLHQLSRSFHGE---VHMRQVS---RDSYVSALNEFKGKEIHNIIIDTNSNGI 207
            |.||:|....:..:..|.:.:..:   |.:||:.   ..:|.:.|...|..|...||:..:...:
Mosquito   179 FTILYESGPWLPGISDLLKMYDPKGYTVTVRQLDLGLNGNYRAVLRRVKLSEDKRIILACSIESM 243

  Fly   208 SILLKNILQQQMNEYKYHYLFTSFDLETYDLEDFKYNFVNITSFRLVDTADVGVKQILKDIGLYS 272
            ..:||...|..:....:..:.||.||.|.|||.::|:..|||..||:|..:..:||: .|. |.:
Mosquito   244 PEVLKQAQQVGLLTDHHQIIITSLDLHTIDLEPYQYSGTNITGVRLIDPEEEKIKQV-ADF-LNA 306

  Fly   273 HHIFKKPYLNLHIKKSTI-LESEPALMFDSVYVFAIGLQTL---EQSHSLTLLNISCEEENSWDG 333
            ..|.|.  |.||...:.. :..:.|||:|:|.:||..|:.|   |....|..:::.|::..:|..
Mosquito   307 SQIAKT--LELHDGLNPAKMRVKTALMYDAVLLFAEALKHLIGSEPPRLLEPISLKCDDPTTWKN 369

  Fly   334 GLSLINYLNAVEWKGLTGPIQF-KDGQRVQFKLDLIKLKQHSIVKVGEWTPHGHLNIT----EPS 393
            |.|:|||:.:....|||..|:| ..|.|..|.||||:|....:.|||.|.....||.|    :.:
Mosquito   370 GYSVINYMKSSTIHGLTRSIKFDHQGHRSDFLLDLIELGPAGLEKVGVWNSTEGLNFTRKTEQAA 434

  Fly   394 MFFDAGSM-NVTLVVITILETPYVMMHYGK-NFTGNERFYGFCVDILETISREVGFDYILDLVPD 456
            ...|.|:: |.|.:|:|.:..||.|:.... ..:|||||.||.:|::..:|..:||:|...|..|
Mosquito   435 HAMDDGTLQNRTFLVLTAISPPYGMLKDSPIKLSGNERFEGFGIDLIHELSLMLGFNYTFILQED 499

  Fly   457 RKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPT 521
            ..||:.:.:|.:|||||.:|::::||||:..:|||..|||.:|||.|||||||||||:.||.||.
Mosquito   500 GVYGSLNRDTKKWNGMVQELLEWRADLAITDLTITSDRESAVDFTMPFMNLGISILFRKPTKEPP 564

  Fly   522 RLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFT 586
            .|||||:|.:.::|:|:..||.:||:.::::|::||.||.....|..|...:.||||.::|.|||
Mosquito   565 SLFSFMSPFSKQVWLYLGGAYMMVSMSLFVLGRISPKEWDNPYPCIEEPEELENQFSFSNSMWFT 629

  Fly   587 IGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQ-TE 650
            ||..:||..:|.|:|.:||.::|.|.||:||:|:|||||||||||.|::::||.||||||:. ..
Mosquito   630 IGALLQQGSEIAPKAPATRAVASIWWFFTLIMVSSYTANLAAFLTVEQVVSPINNAEDLAAAGGA 694

  Fly   651 ISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRVNQGNYAFLMESTMLDY 715
            :.||....|||::||:|:...||.|:::.| .......|::..:|::||...|||||||||.::|
Mosquito   695 VKYGAKRDGSTISFFKDAEYGTYAKMYQFM-MANQDLLTSSNPEGLQRVKTENYAFLMESTSIEY 758

  Fly   716 IVQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWKNTDETCTRK 780
            ||:|:|::||||||||.||||||..|.||:|..:|.|:|.|||:|.:..|..||||........:
Mosquito   759 IVERECDVTQIGGLLDDKGYGIAMRKNSPYRSALSEAVLRLQEQGVLTSLKRKWWKEKRGGGACE 823

  Fly   781 NTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFWYN-FRYNYEATPSQSVVNNKYNQDG- 843
            ||.::..|.:|.|.::|||||:||.|.:.|..|:|.|...: .|...|...|.|       :||
Mosquito   824 NTMEEGGALALELANVGGVFVLLIVGCVAALFVSFCEMLCDVHRRTRELKQSTS-------EDGA 881

  Fly   844 ---------------------------------ILESERNYTPPDRSFWIEIAEELRYASWCMNK 875
                                             |....|.:..|.|.   |:..|||:.:.|...
Mosquito   882 EELDMDNVGGVFFVLFVGCSFASLFGCCELFFVIAHRARRHKVPFRE---ELMAELRFVAKCHGN 943

  Fly   876 QKRPALTRTCSKCTIP 891
            .| |...|..|..:.|
Mosquito   944 TK-PVRHRKSSSASGP 958

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	111/380 (29%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	179/370 (48%)
		Lig_chan	532..806	CDD:459656	129/274 (47%)
LOC1273165	XP_061503118.1	None