Protein Alignment Ekar and LOC1270566

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_309276.5
• Gene: LOC1270566 / 1270566
• VectorBaseID: AGAMI1_006865
• Length: 939
• Species: Anopheles gambiae
• Alignment Length: 895
• Identity: 327/895 - (36%)
• Similarity: 499/895 - (55%)
• Gaps: 99/895 - (11%)

  Fly    23 VRIGAIFSNQPG-MYNSELAFRYAIHRLNMDK---SLLPETTVDYYVEYVNRFDSFETVQKVCKL 83
            :.:||||...|. .|.||:||||||.|:||.:   .|:|      .|.||:..||::|.:|||:|
Mosquito    33 IPVGAIFHQVPDHSYESEIAFRYAIERVNMHEKHFELVP------IVRYVSPDDSYKTERKVCEL 91

  Fly    84 IRVGVQAVFSPTDSVLATHINSICDALDIPNI---------GRSAHD---FSINVYPSKQLVNYA 136
            ...||.|||.|:..:.:..:.|||..|:||:|         |....|   .:||:||...:::.|
Mosquito    92 AAEGVTAVFGPSSILTSGIVGSICKTLEIPHIITHWDPEPFGGLDPDLQAMTINLYPEADVLSRA 156

  Fly   137 FNDVIQYLNWTRFGILHEKENGIINLHQLSRSFHG----EVHMRQV-SRDSYVSALNEFKGKEIH 196
            ..|:|...:|..|.|:::.:.|::.|..:.: .||    .:.:||: ....|...|.:.:.....
Mosquito   157 LADLIVDYSWKSFTIIYDSDEGLMRLKDILQ-IHGPSDSPITVRQIDDNPDYRPLLKDIQTSGES 220

  Fly   197 NIIIDTNSNGISILLKNILQQQMNEYKYHYLFTSFDLETYDLEDFKYNFVNITSFRLVDTADVGV 261
            :||::...:.|..||:...:.:|.|....|:.||.|..|.|.|:.:|:..|||:.||:||....:
Mosquito   221 HIILEIRPDRILELLRQAKEVKMLEEYQSYIITSLDAHTIDFEELRYSRSNITALRLMDTKSFDI 285

  Fly   262 KQILKD-----------IGLYSHHIFKKPYLNLHIKKSTILESEPALMFDSVYVFAIGLQTLEQS 315
            |..:.|           ..:...|:                .:|.||..|:|.::|..::.|:.:
Mosquito   286 KNAVHDWEQGEARMKRQFRVSPEHV----------------HTESALYNDAVKIYATAIRELDAT 334

  Fly   316 HSLTLLNISCEEEN--SWDGGLSLINYLNAVEWKGLTGPIQFKD-GQRVQFKLDLIKL-KQHSIV 376
            ..:|...:||..:|  .|..||.:|||:......|:||||.|.| |:|..|.||:|:| |.....
Mosquito   335 EEITPSKLSCGSKNLRQWPFGLRIINYMKVKTEHGITGPIIFDDFGRRAHFHLDIIELSKDEGFK 399

  Fly   377 KVGEWTPHGHLNITEP-----SMFFDAGSMNVTLVVITILETPYVMMHY---GKNFTGNERFYGF 433
            |:..|.|...:|.|..     |...:: ..|.|.:|.:.:..|::|...   |:...||.||.|:
Mosquito   400 KIATWDPTHGVNYTRSQGEVYSQIVES-LQNKTFIVASRIGAPFLMFKEKKDGEFLEGNNRFEGY 463

  Fly   434 CVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVI 498
            .:::::.||:.:||.|.::||||.|||:.:..|.:|:|:|..|:..||||||..:||||.|.:.:
Mosquito   464 SLELIDGISKILGFQYRMELVPDGKYGSYNKVTKKWDGLVKHLLDRKADLAVCDLTITYERRTAV 528

  Fly   499 DFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCI 563
            |||.|||.||||||:..|..:|..||||::||::::|||...||..||:.::::.:::|.:|:..
Mosquito   529 DFTMPFMTLGISILYAKPVQQPKDLFSFLSPLSLDVWIYTATAYLGVSVLLFVLSRMAPADWENP 593

  Fly   564 NACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAA 628
            :.|..:|..:.|.:.:.::.|.|:|:.|.|..||.|:|:|||:::..|.||:||:::||||||||
Mosquito   594 HPCKQDNDEVENIWDMLNALWLTMGSIMGQGCDILPKAISTRLVAGMWWFFALIMLSSYTANLAA 658

  Fly   629 FLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYE 693
            |||.|||...||:|||||.|::|.||.|..||||.||:.|...||:::|.||::.:||.||.:.:
Mosquito   659 FLTMERMDATIESAEDLAKQSKIKYGVLMGGSTMAFFQTSNFSTYQRMWASMESVRPSVFTKSND 723

  Fly   694 DGIKRVNQGN--YAFLMESTMLDYIVQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILEL 756
            :|..||.:|.  ||||||||.|:||.:|.|:|||||||||:||||||.|..||:|..||.|:|::
Mosquito   724 EGRDRVIKGKRMYAFLMESTSLEYITERYCDLTQIGGLLDSKGYGIAMPVNSPYRTAISGAVLKM 788

  Fly   757 QERGDIQMLYDKWWKNT--DETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFW 819
            ||.|.:..|..:|||..  ...||....|  :..|.||:.::|||||||..|...|.::...||.
Mosquito   789 QEEGKLHQLKTRWWKEMRGGGQCTEVPNS--AGENELGIGNVGGVFVVLALGCFCAFIIGILEFL 851

  Fly   820 YNFRYNYEATPSQSVVNNKYNQDGILESERNYTPPDRSFWIEIAEELRYA 869
            :|.|.                    :..|...||     |..:..|:::|
Mosquito   852 WNVRK--------------------VAVEEKITP-----WDALKAEMKFA 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	123/401 (31%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	175/373 (47%)
		Lig_chan	532..806	CDD:459656	131/277 (47%)
LOC1270566	XP_309276.5	None