Protein Alignment Ekar and si:ch211-264f5.8

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_017207885.1
• Gene: si:ch211-264f5.8 / 100331381
• ZFINID: ZDB-GENE-081104-209
• Length: 1063
• Species: Danio rerio
• Alignment Length: 874
• Identity: 321/874 - (36%)
• Similarity: 481/874 - (55%)
• Gaps: 81/874 - (9%)

  Fly     2 LIASGFLLFQFLSYGLG------VPPL--VRIGAIFSNQPGMYNSE-LAFRYAIHRLN--MDKSL 55
            |:.|..|||..|...:.      ||.|  ||:.||..:|......| ||...|...:|  |:...
Zfish     7 LLLSIHLLFLVLLLTMAPSSHSQVPALSAVRMAAILDDQSACGRGERLALALARENINSLMEGPA 71

  Fly    56 LPETTVDYYVEYVNRFDSFETVQKVCKLIRVGVQAVFSPTDS-VLATHINSICDALDIPNIGRSA 119
            .....||.:  .:.|...:||...:|:::..||.:|..|..| ...:.::.||...:||:|....
Zfish    72 RARVEVDIF--ELQRDSQYETTDTMCQILPKGVVSVIGPASSPASGSTVSHICGEKEIPHIKIGP 134

  Fly   120 HD---------FSINVYPSKQLVNYAFNDVIQYLNWTRFGILHEKENGIINLHQLSRSFHGEVHM 175
            .:         .|:.:|||.:.::.|...:::...:....::..|...::.|.:|.|.|
Zfish   135 EETPRLPYLRFASVTLYPSNEDLSLAIGAILRSFGYPTASLICAKAECLLRLEELVRHF------ 193

  Fly   176 RQVSRDSY-----------VSALNEFKGKEIHNIIIDTNSNGISILLKNILQQQMNEYKYHYLFT 229
             .:||::.           ...|.|.:..::..||||.|::...::||...:..|....|.|:.|
Zfish   194 -LISRETLSVRMLDENLDPTPLLKEIRDDKVATIIIDANASVSILILKKASELGMTSAFYKYILT 257

  Fly   230 SFDLETYDLEDFKYNFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYLNLHIKKSTILESE 294
            :.|.....|:|...:..||..|.:::.:.....:.::.             |||..::...|...
Zfish   258 TMDFPLLRLDDVVNDQSNIVGFSMLNNSHPFYLEFIRS-------------LNLSWREGCDLSPY 309

  Fly   295 P------ALMFDSVYVFAIGLQTLEQSHSLTLLNISCEEENSWDGGLSLINYLNAVEWKGLTGPI 353
            |      |||||:|:|....::.|.:|..:.:..:||.....|..|.||:|||..||:.||||.:
Zfish   310 PGPALSSALMFDAVHVVVGAVRELNRSQEIGVKPLSCTSSLIWQHGTSLMNYLRMVEYDGLTGRV 374

  Fly   354 QFKD-GQRVQFKLDLIKLKQHSIVKVGEWTPHGHLNITEPSMFFDAGS--MNVTLVVITILETPY 415
            :|.. |||..:.|.:::..:....::|.|..:..|.:...|:..:...  .|.||.|.||||.||
Zfish   375 EFNSKGQRTNYTLRILEKFKGGHKEIGVWYSNNTLAMNSTSLDINTSETLANKTLTVTTILENPY 439

  Fly   416 VMM--HYGKNFTGNERFYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMK 478
            ||.  :| ::|.|::::.|||||:|..::..:.|.:.:.||.|..|||.:| .|.|.|||.:|:.
Zfish   440 VMRKENY-QDFQGSDQYEGFCVDMLRELADILKFSFRIKLVDDGLYGAPEP-NGSWTGMVGELIN 502

  Fly   479 YKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYF 543
            .||||||...|||..||.||||:|||||||||||::|........|||::|.:..:|:::|:||.
Zfish   503 RKADLAVAGFTITSEREKVIDFSKPFMNLGISILYRVHIGRKPGYFSFLDPFSPAVWLFMLLAYL 567

  Fly   544 LVSLCIYIVGKLSPIEWKCINAC-----DLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMS 603
            .||..:::..:|||.||.....|     ||    :.||::|.:|.||.||.||||..:|.|||:|
Zfish   568 AVSCVLFLAARLSPYEWYNPFPCWRERRDL----LENQYTLGNSLWFPIGGFMQQGSEIMPRALS 628

  Fly   604 TRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRDS 668
            ||.:|..|..|:|||::|||||||||||.:||..|||:|||||.||.|.|||:..|||||||.:|
Zfish   629 TRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESAEDLADQTNIQYGTIQGGSTMTFFMNS 693

  Fly   669 VIETYKKIWRSMDNKKPSAFTTTYEDGIKRVNQGNYAFLMESTMLDYIVQRDCNLTQIGGLLDTK 733
            ..:||:::|..|.:|:||.|..:.|:||.||....||||:||||.:|..:.:|||||||||||||
Zfish   694 RYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSKYAFLLESTMNEYHRRLNCNLTQIGGLLDTK 758

  Fly   734 GYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKANSLGLESIGG 798
            ||||..|.|||:||:|:|.||:|||...:::|..:||:.  ..|.::   :..:|..||:::|||
Zfish   759 GYGIGMPLGSPFRDEITLGILQLQENNRLEILKRRWWEG--GKCLKE---EDHRAKGLGMDNIGG 818

  Fly   799 VFVVLIAGIIVAAVVAFFEFWYNFRYNYE 827
            :|||||.|:|:|..||..||.::.|.:.|
Zfish   819 IFVVLICGLIIAVFVAIMEFVWSTRRSAE 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	94/396 (24%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	194/375 (52%)
		Lig_chan	532..806	CDD:459656	141/278 (51%)
si:ch211-264f5.8	XP_017207885.1	PBP1_iGluR_Kainate_KA1_2	35..413	CDD:380616	95/399 (24%)
		Periplasmic_Binding_Protein_Type_2	426..796	CDD:473866	194/375 (52%)