Protein Alignment RunxA and runx2b

DIOPT Version :10

• Sequence 1: NP_001259747.1
• Gene: RunxA / 4379817
• FlyBaseID: FBgn0083981
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: XP_073788384.1
• Gene: runx2b / 405788
• ZFINID: ZDB-GENE-040629-4
• Length: 646
• Species: Danio rerio
• Alignment Length: 394
• Identity: 150/394 - (38%)
• Similarity: 194/394 - (49%)
• Gaps: 91/394 - (23%)

  Fly    86 RTLGDFLTEHPGELIRTSSPLFVCTVLPPHWRSNKTLPVAFKVVSLGDIMDGTMVTVRAGNDENY 150
            |::.:.:.:||.||:||.||.|:|:|||.|||.|||||||||||:||::.|||:|||.|||||||
Zfish   244 RSMAEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENY 308

  Fly   151 CAELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTITVSTNPPHIATYNKAIKVTVDGPREPRS 215
            .|||||.:.|||||||:||||||||||||||||||||||.||||.:|||::|||||||||||||.
Zfish   309 SAELRNASGVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR 373

  Fly   216 --------------KTMLSLLGQQQQFHFAF---GQRPFHFSTDPLSGFRMPPIGNC------QS 257
                          ...||.|.:.:|.....   .|.|....:.|.|   ..|.|..      |:
Zfish   374 HRPKLDDSPKAGLFSDRLSELERIRQTTMRVTVPTQTPRPSLSSPNS---YTPQGQTQITDPRQA 435

  Fly   258 ASNTHWGYGSAASAYSPYLASSGLSSCTTP----------------------------------- 287
            .|:..|.|.....:|...:||..:.| |||
Zfish   436 QSSPPWSYDQTYPSYLSPMASPSVHS-TTPLSSSRATGLPSISDVPRRLPGSTDLSPFPGQFERQ 499

  Fly   288 -------TSAQFNNPAL----GFTCSSNDQSNNQDFGGATNRDCV-PMLPDSTASDLDQHLSS-- 338
                   |.::|::|.:    .||.:....:.....|.|.....: |..|.||.|......||
Zfish   500 FPAFSSLTESRFSSPRMHYPATFTYTPTPVTTGMSLGSAHYHTYLPPPYPGSTQSQSGPFQSSST 564

  Fly   339 ---LVGSTSGQMTHHSLLGAGGQTSISSTVNGASGGGSAGAGTA-------GGGAGSGGGAGGGA 393
               ..|::||  ::...:..||:.|.:..:...:   ||..||:       ....||||..|.|:
Zfish   565 PYLYYGASSG--SYQFSMVPGGERSPTRMMPPCT---SASTGTSLVNPNLPVQADGSGGVEGDGS 624

  Fly   394 GGNS 397
            ..||
Zfish   625 HSNS 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RunxA	NP_001259747.1	Runt	88..216	CDD:459963	96/141 (68%)
runx2b	XP_073788384.1	None