Protein Alignment Tdg and Tdg-ps

DIOPT Version :10

• Sequence 1: NP_651925.1
• Gene: Tdg / 43796
• FlyBaseID: FBgn0026869
• Length: 1738
• Species: Drosophila melanogaster
• Sequence 2: XP_006521693.1
• Gene: Tdg-ps / 545124
• MGIID: 3645587
• Length: 421
• Species: Mus musculus
• Alignment Length: 436
• Identity: 162/436 - (37%)
• Similarity: 227/436 - (52%)
• Gaps: 80/436 - (18%)

  Fly   641 YSFMGEELHMHSPSHRHLDAVTTGPGRYGILVSNDTPECLSREMYRHSQQSTTVLEQTDSSSCGI 705
            |||:.:::....|:.    ||.||                 :::...:....||.||...:...:
Mouse    18 YSFLFQQMMAEVPNM----AVMTG-----------------QQVPAVAPNMATVTEQQVPTDAPV 61

  Fly   706 NFKP---MPKKRGRKKKLVAVNADTSQMTTPVDQQKVSAGRADCEDGGGDQAAKPKERK------ 761
            . :|   .||:|.||.:       .::...||:.:|    .|..:..|....:|.|:.|
Mouse    62 Q-EPAPEAPKRRKRKPR-------AAEPQEPVEPKK----PATSKKSGKSTKSKEKQEKITDAFK 114

  Fly   762 ---KHDRFNGMSEEEVIKRTIPDHLCDNLDIVIVGINPGLFAAYKGHHYAGPGNHFWKCLYLAGL 823
               |.|||||:||.|::.:|:||.|..||||||:||||||.||||||||.||||||||||:::||
Mouse   115 VKRKVDRFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGL 179

  Fly   824 TQEQMSADEDHKLI-KQGIGFTNMVARATKGSADLTRKEIKEGSRILLEKLQRFRPKVAVFNGKL 887
            ::.|::...||.|. |.||||||||.|.|.||.||:.||.:||.|||::|||:::|::||||||.
Mouse   180 SEVQLNHMNDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKC 244

  Fly   888 IFEVFSGK------KEFHFGRQPDRVDGTDTFIWVMPSSSARCAQLPRAADKVPFYAALKKFRDF 946
            |:|:||.:      |...||.||.::..|:|..:|||||||||||.|||.|||.:|..||..||.
Mouse   245 IYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQ 309

  Fly   947 LNGQIPHIDESECVFTDQRIRLCSAQQQVDIVGKINKTHQP--------PLGDHPSSLTVVSNCS 1003
            |.|...:.|..|..:|   ..|..||:....:....:.:.|        ..|::|        |:
Mouse   310 LKGIERNADVQEVQYT---FDLQLAQEDAKKMAVKEEKYDPGYKAAYGGAYGENP--------CN 363

  Fly  1004 GPIAGDAECGIVAEES---------DQVQSEKMIPQMDPTVPSSSN 1040
            |...|.|..|:.|..:         |....:.|.......:||.:|
Mouse   364 GEPCGIASNGLTAHSAEPRGEAAPGDVPNGQWMAQSFAEQIPSFNN 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdg	NP_651925.1	UDG-like	714..962	CDD:444933	129/263 (49%)
		motif A	793..797	CDD:381679	3/3 (100%)
Tdg-ps	XP_006521693.1	mug	2..340	CDD:273154	148/357 (41%)
		motif A	149..153	CDD:381679	3/3 (100%)