Protein Alignment: Thd1 and Tdg

• Sequence 1: NP_001259060.1
• Gene: Thd1
• FlyBaseID: FBgn0026869
• Length: 1738
• Species: Drosophila melanogaster
• Sequence 2: NP_766140.2
• Gene: Tdg
• MGIID: 108247
• Length: 421
• Species: Mus musculus
• Alignment Length: 451
• Identity: 168/452 (37%)
• Similarity: 232/452 (51%)
• Gaps: 80/452 (18%)

  Fly   626 SEGTRCSSHASVVDPYSFMGEELHMHSPSHRHLDAVTTGPGRYGILVSNDTPECLSREMYRHSQQ 690
            :|..|..|...|...|||..:::....|:.    |||||                 :::...:..
Mouse     3 AEAARSYSLEQVQALYSFPFQQMMAEVPNM----AVTTG-----------------QQVPAVAPN 46

  Fly   691 STTVLEQTDSSSCGINFKP---MPKKRGRKKKLVAVNADTSQMTTPVDQQKVSAGRADCEDGGGD 752
            ..||.||.......:. :|   .||:|.||.:       .::...||:.:|    .|..:..|..
Mouse    47 MATVTEQQVPEDAPVQ-EPAPEAPKRRKRKPR-------AAEPQEPVEPKK----PATSKKSGKS 99

  Fly   753 QAAKPKERK---------KHDRFNGMSEEEVIKRTIPDHLCDNLDIVIVGINPGLFAAYKGHHYA 808
            ..:|.|:.|         |.|||||:||.|::.:|:||.|..||||||:||||||.||||||||.
Mouse   100 TKSKEKQEKITDAFKVKRKVDRFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYP 164

  Fly   809 GPGNHFWKCLYLAGLTQEQMSADEDHKLI-KQGIGFTNMVARATKGSADLTRKEIKEGSRILLEK 872
            ||||||||||:::||::.|::..:||.|. |.||||||||.|.|.||.||:.||.:||.|||::|
Mouse   165 GPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQK 229

  Fly   873 LQRFRPKVAVFNGKLIFEVFSGK------KEFHFGRQPDRVDGTDTFIWVMPSSSARCAQLPRAA 931
            ||:::|::||||||.|:|:||.:      |...||.||.::..|:|..:|||||||||||.|||.
Mouse   230 LQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQ 294

  Fly   932 DKVPFYAALKKFRDFLNGQIPHIDESECVFTDQRIRLCSAQQQVDIVGKINKTHQP--------P 988
            |||.:|..||..||.|.|...:.|..|..:|   ..|..||:....:....:.:.|        .
Mouse   295 DKVHYYIKLKDLRDQLKGIERNADVQEVQYT---FDLQLAQEDAKKMAVKEEKYDPGYEAAYGGA 356

  Fly   989 LGDHPSSLTVVSNCSGPIAGDAECGIVAEE---------SDQVQSEKMIPQMDPTVPSSSN 1040
            .|::|        |:|...|.|..|:.|..         ||....:.|.......:||.:|
Mouse   357 YGENP--------CNGEPCGIASNGLTAHSAEPRGEAAPSDVPNGQWMAQSFAEQIPSFNN 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Thd1	NP_001259060.1	UDG_like	714..962	CDD:294330	129/264 (49%)
Tdg	NP_766140.2	mug	2..340	CDD:273154	153/373 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C316586519
eggNOG	1	0.900				E1_COG3663
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0003740
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900				OOG5_130139
Panther	1	1.100			LDO	PTHR12159
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1493
TreeFam	1	0.960
	7	6.820