Protein Alignment Tdg and Tdg

DIOPT Version :10

• Sequence 1: NP_651925.1
• Gene: Tdg / 43796
• FlyBaseID: FBgn0026869
• Length: 1738
• Species: Drosophila melanogaster
• Sequence 2: NP_766140.2
• Gene: Tdg / 21665
• MGIID: 108247
• Length: 421
• Species: Mus musculus
• Alignment Length: 451
• Identity: 168/451 - (37%)
• Similarity: 232/451 - (51%)
• Gaps: 80/451 - (17%)

  Fly   626 SEGTRCSSHASVVDPYSFMGEELHMHSPSHRHLDAVTTGPGRYGILVSNDTPECLSREMYRHSQQ 690
            :|..|..|...|...|||..:::....|:.    |||||                 :::...:..
Mouse     3 AEAARSYSLEQVQALYSFPFQQMMAEVPNM----AVTTG-----------------QQVPAVAPN 46

  Fly   691 STTVLEQTDSSSCGINFKP---MPKKRGRKKKLVAVNADTSQMTTPVDQQKVSAGRADCEDGGGD 752
            ..||.||.......:. :|   .||:|.||.:       .::...||:.:|    .|..:..|..
Mouse    47 MATVTEQQVPEDAPVQ-EPAPEAPKRRKRKPR-------AAEPQEPVEPKK----PATSKKSGKS 99

  Fly   753 QAAKPKERK---------KHDRFNGMSEEEVIKRTIPDHLCDNLDIVIVGINPGLFAAYKGHHYA 808
            ..:|.|:.|         |.|||||:||.|::.:|:||.|..||||||:||||||.||||||||.
Mouse   100 TKSKEKQEKITDAFKVKRKVDRFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYP 164

  Fly   809 GPGNHFWKCLYLAGLTQEQMSADEDHKLI-KQGIGFTNMVARATKGSADLTRKEIKEGSRILLEK 872
            ||||||||||:::||::.|::..:||.|. |.||||||||.|.|.||.||:.||.:||.|||::|
Mouse   165 GPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQK 229

  Fly   873 LQRFRPKVAVFNGKLIFEVFSGK------KEFHFGRQPDRVDGTDTFIWVMPSSSARCAQLPRAA 931
            ||:::|::||||||.|:|:||.:      |...||.||.::..|:|..:|||||||||||.|||.
Mouse   230 LQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQ 294

  Fly   932 DKVPFYAALKKFRDFLNGQIPHIDESECVFTDQRIRLCSAQQQVDIVGKINKTHQP--------P 988
            |||.:|..||..||.|.|...:.|..|..:|   ..|..||:....:....:.:.|        .
Mouse   295 DKVHYYIKLKDLRDQLKGIERNADVQEVQYT---FDLQLAQEDAKKMAVKEEKYDPGYEAAYGGA 356

  Fly   989 LGDHPSSLTVVSNCSGPIAGDAECGIVAEE---------SDQVQSEKMIPQMDPTVPSSSN 1040
            .|::|        |:|...|.|..|:.|..         ||....:.|.......:||.:|
Mouse   357 YGENP--------CNGEPCGIASNGLTAHSAEPRGEAAPSDVPNGQWMAQSFAEQIPSFNN 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdg	NP_651925.1	UDG-like	714..962	CDD:444933	129/263 (49%)
		motif A	793..797	CDD:381679	3/3 (100%)
Tdg	NP_766140.2	mug	2..340	CDD:273154	149/355 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..108		10/65 (15%)
		motif A	149..153	CDD:381679	1/3 (33%)