Protein Alignment Tdg and Tdg

DIOPT Version :10

• Sequence 1: NP_651925.1
• Gene: Tdg / 43796
• FlyBaseID: FBgn0026869
• Length: 1738
• Species: Drosophila melanogaster
• Sequence 2: NP_001375432.1
• Gene: Tdg / 114521
• RGDID: 620959
• Length: 410
• Species: Rattus norvegicus
• Alignment Length: 368
• Identity: 151/368 - (41%)
• Similarity: 204/368 - (55%)
• Gaps: 55/368 - (14%)

  Fly   711 PKKRGRKKKLVAVNADTSQMTTPVDQQKVSAGRADCEDGGGDQAAKPKERK---------KHDRF 766
            ||:|.||.:       .::...||:.:|.:|.:    ..|....:|.|:.|         |.|||
  Rat    54 PKRRKRKTR-------AAEAQDPVEPKKPAASK----KSGKSTKSKEKQEKITDTFKVKRKVDRF 107

  Fly   767 NGMSEEEVIKRTIPDHLCDNLDIVIVGINPGLFAAYKGHHYAGPGNHFWKCLYLAGLTQEQMSAD 831
            ||:||.|::.:|:||.|..||||||:||||||.||||||||.||||||||||:::||::.|::..
  Rat   108 NGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHM 172

  Fly   832 EDHKLI-KQGIGFTNMVARATKGSADLTRKEIKEGSRILLEKLQRFRPKVAVFNGKLIFEVFSGK 895
            :||.|. |.||||||||.|.|.||.||:.||.:||.|||::|||:::|::||||||.|:|:||.:
  Rat   173 DDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKE 237

  Fly   896 ------KEFHFGRQPDRVDGTDTFIWVMPSSSARCAQLPRAADKVPFYAALKKFRDFLNGQIPHI 954
                  |...||.||.::..|:|..:|||||||||||.|||.|||.:|..||..||.|.|.....
  Rat   238 VFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERST 302

  Fly   955 DESECVFTDQRIRLCSAQQQVDIVGKINKTHQP--------PLGDHPSSLTVVSNCSGPIAGDAE 1011
            |..|..:|   ..|..||:.........:.:.|        ..|::|        |:|...|.|.
  Rat   303 DVQEVQYT---FDLQLAQEDAKRTAVKEEKYDPGYEAAYGGACGENP--------CNGEPCGFAS 356

  Fly  1012 CGIVAEE---------SDQVQSEKMIPQMDPTVPSSSNATDGK 1045
            .|:.|..         ||....:.|.......:||.:|...|:
  Rat   357 NGLTANSAELGGESAPSDVPNGQWMAQSFAEQIPSFNNCGTGE 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdg	NP_651925.1	UDG-like	714..962	CDD:444933	129/263 (49%)
		motif A	793..797	CDD:381679	3/3 (100%)
Tdg	NP_001375432.1	mug	2..325	CDD:273154	135/286 (47%)
		motif A	134..138	CDD:381679	2/3 (67%)