Protein Alignment zfh2 and Dr

DIOPT Version :10

• Sequence 1: NP_524623.2
• Gene: zfh2 / 43795
• FlyBaseID: FBgn0004607
• Length: 3005
• Species: Drosophila melanogaster
• Sequence 2: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 538
• Identity: 119/538 - (22%)
• Similarity: 187/538 - (34%)
• Gaps: 141/538 - (26%)

  Fly  1731 AGNAVSGPSALNNSITTSTATSASGLGDTHLTSGVSSIPVDSGKATAVPPQTQLNANANSQQLAS 1795
            |||.:         ||:|::.|.|..|     |.:||..:.|...|.:.|......||    |||
  Fly    31 AGNLI---------ITSSSSNSGSNSG-----SNMSSGNMTSSNLTNLSPSHPAGLNA----LAS 77

  Fly  1796 NQKRARTRITDDQLKILRAHFDINNSPSEESIMEMSQKANLPMKVVKHWFRNTLFKERQRNKDSP 1860
            ....:...:...| .:|:.|     ...::...:..|.|.|.:..| |...:.|.|...|
  Fly    78 PTSPSALLLAHQQ-HLLQQH-----QQHQQQQQQQQQAAALQLAAV-HPPAHHLHKTTSR----- 130

  Fly  1861 YNFNNPPSTTLNLEEYERT--GQAKVTPLNDTCSVAVTGPMT--SSTISLPPSG----------- 1910
              .:|....:|..:...||  .||...|.|.|.| |.|.|::  |||...||:.
  Fly   131 --LSNFSVASLLADTRPRTPPNQAADGPQNLTSS-AATSPISQASSTPPPPPASAAAQVPANTFH 192

  Fly  1911 ------------NINLSSKENATSKVLAA--------GKANASGPVTFSATVPVSTPLSRPESTN 1955
                        ..:.::..:|..:.:||        ..|.|:.|...:::.|.||||.  .:..
  Fly   193 PAAVAHHAHLLQAAHAAAAAHAQHQAMAAQLRQQQQQADARANSPPASTSSTPSSTPLG--SALG 255

  Fly  1956 SSGNISDYIGNNIFFGQLGSKEQILPYSLDGQIKSEPQDDMIGATDFAYQTKQHSSFSFLKQQQD 2020
            |.||::.....|.....|||       ..|.::  |..::|:          |.......:::..
  Fly   256 SQGNVASTPAKNERHSPLGS-------HTDSEL--EYDEEML----------QDHEADHDEEEDS 301

  Fly  2021 LVDPPEQCLTNQNAD----TAQDQSLLAGSSLAS----NCQSQQQINIFETKSESGSSDVLSRPP 2077
            :||     :.:.|||    :..|....:|.||.|    ...|..|..|. :.:...|..|..||.
  Fly   302 IVD-----IEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTIL-SPAALASGHVPIRPT 360

  Fly  2078 SPNSGAAGNVYGSMNDLLNQQLENMGSNM-----------GPPKKMQIVGKTFEKNVAPMVTSGS 2131
            ..::.||..|..:          .||..:           |||......|...:.|..|     .
  Fly   361 PFSALAAAAVAWT----------GMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEPP-----R 410

  Fly  2132 VSTQFESNSSNSSSSSSSTSGGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPR 2196
            :......:..|            |..||.||..|:..|::.|....|...::....|..|.|:..
  Fly   411 IKCNLRKHKPN------------RKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTET 463

  Fly  2197 VIVVWFQNARQKQRKIYE 2214
            .:.:||||.|.|.:::.|
  Fly   464 QVKIWFQNRRAKAKRLQE 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zfh2	NP_524623.2	C2H2 Zn finger	561..581	CDD:275368
		C2H2 Zn finger	616..633	CDD:275368
		C2H2 Zn finger	1515..1542	CDD:275371
		C2H2 Zn finger	1543..1564	CDD:275371
		Homeodomain	1798..1857	CDD:459649	11/58 (19%)
		Homeodomain	2155..2211	CDD:459649	18/55 (33%)
		Homeodomain	2761..2817	CDD:459649
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	18/55 (33%)