Protein Alignment Asator and VRK1

DIOPT Version :10

• Sequence 1: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: XP_047287708.1
• Gene: VRK1 / 7443
• HGNCID: 12718
• Length: 422
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 124/492 - (25%)
• Similarity: 199/492 - (40%)
• Gaps: 140/492 - (28%)

  Fly   133 PRNQVAVAAKDGILVDVKAKESVKMTSEDLLQPGHVV----KERWKVVRKIGGGGFGEIYEGQDL 193
            ||.:.|.|.:         :.|.|....:....|.::    |:.|||...||.||||.||.. |:
Human     4 PRVKAAQAGR---------QSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DM 58

  Fly   194 ITREQV------ALKVE---------------SARQPKQVLK-MEVAVLKKLQGKEHVCRFIGCG 236
            .:.|.|      .:|||               .|.:|:|:.| :....||.|    .|.::.|.|
Human    59 NSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYL----GVPKYWGSG 119

  Fly   237 RNDR----FNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPS 297
            .:|:    :.:::|...|.:|.::..|..: .||..|.|:|.|:||..:|.||...::|.|||.|
Human   120 LHDKNGKSYRFMIMDRFGSDLQKIYEANAK-RFSRKTVLQLSLRILDILEYIHEHEYVHGDIKAS 183

  Fly   298 NFSVGRLPY-NCRRVYMLDFGLARQYTTGTGEVRCPRAA---------AGFRGTVRYASINAHRN 352
            |.   .|.| |..:||::|:|||.:|        ||...         ....||:.:.||:||..
Human   184 NL---LLNYKNPDQVYLVDYGLAYRY--------CPEGVHKEYKEDPKRCHDGTIEFTSIDAHNG 237

  Fly   353 REMGRHDDLWSLFYMLVEFVNGQLPWR-KIKDKEQVGLTKEKYDHRILL--------KHLPSDLK 408
            ....|..||..|.|.:::::.|.|||. .:||.:.|..:|.:|...|..        |:.|.::.
Human   238 VAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA 302

  Fly   409 QFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISATGNPSIPIKSD 473
            :::|.::.|.|.::|.|..|..:..:.:|..|.|:..     |:|.:.:.|
Human   303 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDG-----KLDLSVVEN-------------- 348

  Fly   474 YMHGNITQMTVAASNASGTEYIRKRAEIETAHITATDPLNIKEKVDKNCNATSLAQPAKGSGEPM 538
               |.:...|:..         :::.|||.                              |.||.
Human   349 ---GGLKAKTITK---------KRKKEIEE------------------------------SKEPG 371

  Fly   539 VQHGNAANNQNITSKGLQQQSTLTNSQVAIANIQSAP 575
            |:....:|.|  |.:.:|.:|  ..||.||....|.|
Human   372 VEDTEWSNTQ--TEEAIQTRS--EESQGAIHRSMSQP 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	90/305 (30%)
VRK1	XP_047287708.1	STKc_VRK1	28..328	CDD:271024	92/316 (29%)