Protein Alignment Asator and ttbk2b

DIOPT Version :10

• Sequence 1: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: NP_001313220.1
• Gene: ttbk2b / 569881
• ZFINID: ZDB-GENE-030131-8246
• Length: 928
• Species: Danio rerio
• Alignment Length: 1056
• Identity: 350/1056 - (33%)
• Similarity: 490/1056 - (46%)
• Gaps: 223/1056 - (21%)

  Fly   154 SVKMTSEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVA 218
            :|:.|  |:|..|.:|:|||:|::||||||||||||..|.:.:..||||||||:|||||||||||
Zfish     4 TVEQT--DILAVGSMVRERWRVLKKIGGGGFGEIYEVLDHVNQVSVALKVESAQQPKQVLKMEVA 66

  Fly   219 VLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIES 283
            |||:||||:|||||:|||||||||||||:|||:|||:|||....|.||:|||||||.|||:||||
Zfish    67 VLKRLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRNMSHGTFSVSTTLRLGRQILEAIES 131

  Fly   284 IHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASIN 348
            ||||||||||||||||::|||...||..||||||||||:|....|||.||..|||||||||||||
Zfish   132 IHSVGFLHRDIKPSNFAMGRLNSTCRTCYMLDFGLARQFTNSCQEVRPPRPVAGFRGTVRYASIN 196

  Fly   349 AHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEH 413
            ||:|:||||||||||||||||||:.|||||||||||||||..||.|:||:||||||.:...|.:|
Zfish   197 AHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKIKDKEQVGNMKETYNHRLLLKHLPDEFSVFFDH 261

  Fly   414 IQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKVDS---TAIGNISATGNPSIPIKSDYM 475
            |.:|.|..:|||.:|:.:|:..||...|.|:|||||||:||   ..:|.::.|..
Zfish   262 ISNLDYYTKPDYQLLMSVFDNSMKSYNVVENDPYDWEKLDSEDTLNVGTLATTAQ---------- 316

  Fly   476 HGNITQMTVA---ASNAS---------GTEYIRKRAEIETAHITATDPL----------NIKEKV 518
              .:|::|.|   .:|||         .||.:.:...:..|...|..|.          :::...
Zfish   317 --QLTRLTPAYLGMANASAIPGDLQRENTEDVLQGERLSEADNCAPIPTQPALGTDVWEDVEHSR 379

  Fly   519 DKNCNATSLAQPAKGSGEPMVQHGNAANNQNITSKGLQQQSTLTNSQVAIANIQSAPSMIEREDV 583
            |:|.|..........|.|...:.||.:.|    |..:|.......|:..:.: ..||.:......
Zfish   380 DRNLNHVQPQIRKVASEEERSKEGNQSPN----SGSIQGSPRRVRSETLLID-HMAPLLRRMRHS 439

  Fly   584 QYTKLE-----EGAPT--KFI-----TMKPNGECDNVDIAAKCIFEQKHVEANDDIVGRASLSGV 636
            |...|:     |..||  :|:     ..:|....|.    |.|..||..:|   |..|.||...|
Zfish   440 QSMGLDKRLTPEPKPTIERFLEAYLGKQRPGLPQDR----AVCRVEQGSLE---DEEGAASSGYV 497

  Fly   637 EQHYKSQIKKHNSPEIANKQIQRTGTVTNDKTSEVNRSTEEQKSTFGRLRVLTAPPMSVHDLPSG 701
            ..:.....::.:|.|....:::........|..|..||....:|:    ..|..|......||
Zfish   498 AVNLSPVPQEGDSQEWVLVELEGGSGSAGSKPDEEERSGISPRSS----SPLALPRTWSDPLP-- 556

  Fly   702 GGHSHQVSDLSGKQDPYAATSNAAP-----------IGINSSSTKFGSQHGQIFGLAAMPPINRR 755
                .:.|:|||..|.:....:..|           ||::              ||..:|.|  :
Zfish   557 ----QRTSNLSGSVDFHTGVCHTGPPFARLPGLSGVIGLS--------------GLRRLPAI--Q 601

  Fly   756 SATSTNL------RPSSSASQRINSGSTIGG--AVGNGSNTA---RSSVAGDHSVTQFALIDDEN 809
            .||..:|      :.||:|.|.:......|.  ...|.|.||   .:.|...:|.::.:...|||
Zfish   602 PATLAHLNRAHLEQSSSAAVQTVQPQQKTGDDFQPNNPSGTAEKEHNHVPAANSPSRSSNKPDEN 666

  Fly   810 VSALQQVTK----------GGALTLASQWKSQFDDSEDTTDNEWNREHQLQPNLEQLIKLDISLP 864
            :.:::...|          ||    .|...:|.:.:..:.|.......:|.|...::...|...|
Zfish   667 MISVKAFDKDVESDSGCPDGG----PSSTPNQGEMTGHSVDAAPASPRELSPRASRIPVRDPDSP 727

  Fly   865 LNEAKPFPQHGVAGTGKLINPPGEAKGRPKRYTLNITGIENYEALRISIPNCWSEPAMGNVLRKG 929
            ..:..|.|          ::|                      :|.:|   |...|:.  :||..
Zfish   728 TRKCFPAP----------LSP----------------------SLSLS---CEHFPSA--LLRDK 755

  Fly   930 LEPPAVQQAAFDDTVYRMDIARNVCVRETYSEITHLARPSTSSVLRNR-----LPSPFKKDSALQ 989
            ...|...:.:.......:.::.:.....:.|:|   .||.:.:::.::     :|.|......|:
Zfish   756 FTFPTGSRGSDWQVEEPLSLSSSSGPLSSKSKI---PRPISPTLVSDQISARFIPRPPPGKPPLR 817

  Fly   990 LNSTNDSLDKSRHRNSLPNVSVNDIFDDLQMKLNLDLGSAIQENNC-----CISGRLEIRVIPKD 1049
            ....|   .:.|:|....:....|:.|:|...:....|..:..:.|     |...|
Zfish   818 TGGEN---RRRRYRIRASSTGDTDLLDNLSQLMQERGGLTVCSSRCQRTTACSLQR--------- 870

  Fly  1050 TSHPDDSVYYDAMGAVKNTPTANEGHDHSDQAVNNCDEMEATSAVIAFPNKSISKIMSPPGR-DA 1113
                          ::.::|:..|| .|| |:.::|.                   .|||.| ..
Zfish   871 --------------SLSSSPSRFEG-AHS-QSPSSCS-------------------ASPPPRISD 900

  Fly  1114 TEERTGASLCSLYSAG 1129
            .....|:..||...||
Zfish   901 LRVNQGSGFCSRVRAG 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	192/260 (74%)
ttbk2b	NP_001313220.1	STKc_TTBK	20..281	CDD:270919	192/260 (74%)
		PHA03307	398..>743	CDD:223039	80/418 (19%)