Protein Alignment Asator and CSNK1G1

DIOPT Version :10

• Sequence 1: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: NP_001316534.1
• Gene: CSNK1G1 / 53944
• HGNCID: 2454
• Length: 475
• Species: Homo sapiens
• Alignment Length: 481
• Identity: 127/481 - (26%)
• Similarity: 223/481 - (46%)
• Gaps: 47/481 - (9%)

  Fly   151 AKESVKMTSEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKM 215
            ::.|...:|..:|..|    ..::|.:|||.|.|||:..|::|.|.|.||:|:|..:.....|.:
Human    26 SRPSGSSSSSGVLMVG----PNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHL 86

  Fly   216 EVAVLKKL----QGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQ 276
            |....|:|    :|...|..|..||   ::|.:|::|.|.:|.:|.....| .|:|.|.|.:.:|
Human    87 EYRFYKQLGSAGEGLPQVYYFGPCG---KYNAMVLELLGPSLEDLFDLCDR-TFTLKTVLMIAIQ 147

  Fly   277 ILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRV-YMLDFGLARQYTTGTGEVRCP-RAAAGFR 339
            :|..:|.:||...::||:||.||.:||.......| :::|||||::|.....:...| |......
Human   148 LLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLT 212

  Fly   340 GTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDK------EQVGLTKEKYDHRI 398
            ||.||.|||.|..:|..|.|||.:|.:|.:.|:.|.|||:.:|..      :::|.||.......
Human   213 GTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEA 277

  Fly   399 LLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDW-EKVDSTAIGNISA 462
            |.::.|.::..:|.:::.|.:.::|||..|..||....:::|......||| .:...|.:|::..
Human   278 LCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHV 342

  Fly   463 TGNPSIPIKSDYMHGNITQMTVAASNASGTEYIRKRAEIETAHITATDPLNIKEKVDKNCNATSL 527
            ....|...:..:.|.:.........|.:.:...|...||:.:..|.|..|......|::..:..:
Human   343 DSGASAITRESHTHRDRPSQQQPLRNQNVSSERRGEWEIQPSRQTNTSYLTSHLAADRHGGSVQV 407

  Fly   528 AQPAKGS---GEPMVQHGNAANNQNITSKGLQQQSTLTNSQVAIANIQSAPSMIEREDVQYTKLE 589
            .....|.   .:|...|.||.    ||:          :::|.:  ::.|..::..:...::: .
Human   408 VSSTNGELNVDDPTGAHSNAP----ITA----------HAEVEV--VEEAKCIMFHKPWHWSQ-S 455

  Fly   590 EGAPTKFITMKPNGECDNVDIAAKCI 615
            .....||:...      |:::..|||
Human   456 SAVKMKFVVFL------NMNVNFKCI 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	91/272 (33%)
CSNK1G1	NP_001316534.1	STKc_CK1_gamma	43..331	CDD:271028	96/291 (33%)
		CK1gamma_C	331..429	CDD:463640	17/101 (17%)