Protein Alignment Asator and ttbk1

DIOPT Version :10

• Sequence 1: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: XP_031758004.1
• Gene: ttbk1 / 101730492
• XenbaseID: XB-GENE-6047610
• Length: 1280
• Species: Xenopus tropicalis
• Alignment Length: 1390
• Identity: 406/1390 - (29%)
• Similarity: 581/1390 - (41%)
• Gaps: 380/1390 - (27%)

  Fly   161 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQG 225
            |:|...:|||:||||::||||||||||||..||:|||.||||||||:||||||||||||||||||
 Frog    22 DILPVSYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQG 86

  Fly   226 KEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFL 290
            |:|||||||||||::||||||||||:|||:|||:||||.|::|||||||.|||::||||||||||
 Frog    87 KDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIESIHSVGFL 151

  Fly   291 HRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREM 355
            |||||||||::||||...|:.||||||||||||..|||||.||..|||||||||||:|||:||||
 Frog   152 HRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGEVRPPRNVAGFRGTVRYASVNAHKNREM 216

  Fly   356 GRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYG 420
            ||||||||||||||||..|||||||||||||||:.|||||||:||||:||:...|||||.:|.|.
 Frog   217 GRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYDHRMLLKHMPSEFHLFLEHISTLDYF 281

  Fly   421 DRPDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISATGNPS---------------IPI 470
            .:|||.|::.:||..||.||:.|::.:||||..:..:.:.|::..|.               .|:
 Frog   282 TKPDYQMIMSVFESSMKERGITENEAFDWEKGGTEILLSTSSSTPPQQNTRQTAAMFGVVNVTPV 346

  Fly   471 KSDYMHGNITQMTVAASNASGTEYIRKRAEIETAHITATDP------LNIKEKVDKNCNATSL-- 527
            ..|.|..| |:..:...:.|..|..........|.||...|      ..|.|:.|.|.|...:
 Frog   347 PGDLMREN-TEDVLQGEHLSDQENAPPVLPCRPADITGQTPNLGFNDTEIWEETDVNRNKLRISI 410

  Fly   528 -----------------AQPAKGSGEPMVQHGNAANNQNITSKGLQQQSTLTNSQV----AIANI 571
                             :.|.:...|.......:...:.:.|....:.||...:::    :..::
 Frog   411 SKTQCLMEEDPSRGGCPSSPVRAPPESPTTQARSLRYRRVNSPESDRLSTAERAELPERRSRMDL 475

  Fly   572 QSAPS----------MIE------------REDVQYTKLEEGAPTKFITMKPNGECDNVDIAAKC 614
            .::||          |:.            |.:|..:...|.....|.:: |..|.::.| :.:.
 Frog   476 PASPSRQACSSQPAQMLSIDTGNADRQGSGRMEVSASVEHEALSNAFRSV-PLAEEEDFD-SKEW 538

  Fly   615 IFEQKHVEANDDIVG-RASLSGVEQHYKSQIKKHNS---------------PEIANKQIQRTGTV 663
            :...|..|..|...| ..|.||.......:::....               |::...:.:...||
 Frog   539 VIIDKETELKDFHPGAEPSTSGTTDEEPEELRPLEEGEDRRRPGGAEAAVRPKVHEARPRAMQTV 603

  Fly   664 TNDKTSEVNRSTEEQKSTFGRLRVLTAPPMSVHDLPSGGGHSHQV---------SDLSGKQDPYA 719
            ..::||..|...:.:...                .|....|||..         ||.||.|....
 Frog   604 AEEETSCRNEGLDSRPDA----------------TPGSPSHSHSTSLTRQRRRESDPSGPQRQVL 652

  Fly   720 ATSN--------AAPIG---------INSSSTKFGSQHGQI----FGLAAMPP---------INR 754
            :..:        ..|:.         |:.|.......| :|    |....:|.         ||.
 Frog   653 SLKHLEMNTVPRVVPLSLPYQDFKKDISDSKEMLRVPH-RIKRVDFSSVVLPAVYAPEPHIIING 716

  Fly   755 RSATSTNLRPSSSASQRINSGSTIGGAV----GNGSNTARSSVAGDHSVTQFALIDDENVSALQQ 815
            |............|.:.......:|..:    |:.|..::.|.                    ::
 Frog   717 RVPHEREEEEEEEAEEEEEEAEFLGEDIDLQSGSSSEVSQKST--------------------ER 761

  Fly   816 VTKGGALTLASQWKSQFDDSEDTTDNEWNREHQLQPNLEQLIKLDISLPLNEAKPFPQHGV---- 876
            ..:|...||.:      ||.:|:.......|:.|:  ||:..|..:.....:.|..|....
 Frog   762 SQEGAPSTLLA------DDQKDSRGKASTAENDLE--LEEGSKTLVLFSPGDMKRSPVTNELMPE 818

  Fly   877 --AGTGKLINPPGEAKGRPKRYTLNITGIENYEALRISIPNCWSEP-AMGNVLRKGLEPPAVQQA 938
              .||..::.|.|| :.:|....|::                 ||| .:.:||:...:|
 Frog   819 VDLGTLAVLTPQGE-RLQPLGSQLDV-----------------SEPGTLSSVLKSEPKP------ 859

  Fly   939 AFDDTVYRMDIARNVCVRETYSEITHLARPSTSSVLRNRLPSPFKKDSALQLNSTNDSLDKSRHR 1003
                                     |.:..:|:|       |||.|
 Frog   860 -------------------------HCSASATAS-------SPFTK------------------- 873

  Fly  1004 NSLPNVSVNDIFDDLQMKLNLDL----GSAIQENNCCISGRLEIRVIPKDTSHPDDSVYYDAMGA 1064
                   |...|..:..|.:|::    |..::.:..|..|:.|..:|.::|...:
 Frog   874 -------VERTFVHIAEKTHLNVMSSNGQLLRLDEHCTPGQFEEPIIEEETEEQE---------- 921

  Fly  1065 VKNTPTANEGHDHSDQAVNNCDEME-----ATSA----VIAFPN--------KSISKIMSPPGRD 1112
                      |...:..:|:..||.     |.||    |.|.|:        .|:|::...|...
 Frog   922 ----------HLRENGNLNSAVEMGEMDSCAVSASHGDVFAEPHVAPSLVNALSLSQLDKEPINL 976

  Fly  1113 ATEERTGASLCSLYSAGVNKLK------LNGNTAPRTQ------FKKGST-----------DGFG 1154
            |.:|.|.....::..| .::||      :|..|.||.:      |.:..|           :.|.
 Frog   977 ACKELTEQEQKNIVFA-TDRLKETEQGPINKATGPRFRSRIPVFFSEEDTGSDRSMSHSAKERFK 1040

  Fly  1155 ENESEFDFPLLNPSKIPVRQSKCASWAGADFISASKPLESAEVPQEIPYHPQSDTTYSVIDSIP- 1218
            :...:.|...|...|..||..:.|| ||:.  |||...:.....:.:......:.|:...||:|
 Frog  1041 KRSKQLDLARLVMEKRQVRLQRLAS-AGSS--SASSSDDRRRTSETLSTTGSEEDTHDSDDSVPR 1102

  Fly  1219 ----------------VR----------KTTYSIALECPP--NISDLTPGLRRRRESTEGKYVTD 1255
                            ||          |:.|.:.   ||  ..|:|...|..:|.......|:.
 Frog  1103 KVGKKKIVTPGKEDGTVRSRIPRPITPVKSNYPVV---PPVATSSNLRESLMAQRFKPSRSVVSG 1164

  Fly  1256 ------PTQLPLKFQRPRSRTSSRT--RGIPNAMLENSDDNGTVMSAEKTGHGHVVKTEGVKNFT 1312
                  |..|.::.....|...|||  :.|..|..::....|..:||....          ::.:
 Frog  1165 GGTELRPKALNMRLPPLSSPVPSRTNVKRINCAPPKSPAAPGRTLSASSRS----------QSLS 1219

  Fly  1313 TSENSSEVNPKCTISPPPGDPKIEN 1337
            .:|:.|....|..|:||...|:.::
 Frog  1220 RTESPSPSRQKRPIAPPKLQPRAQS 1244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	206/260 (79%)
ttbk1	XP_031758004.1	Protein Kinases, catalytic domain	33..294	CDD:473864	206/260 (79%)
		PHA03307	417..>650	CDD:223039	37/250 (15%)
		PHA03247	<1124..1255	CDD:223021	27/134 (20%)