Protein Alignment Asator and ttbk1b

DIOPT Version :10

• Sequence 1: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: XP_021328804.1
• Gene: ttbk1b / 100000353
• ZFINID: ZDB-GENE-100609-5
• Length: 1219
• Species: Danio rerio
• Alignment Length: 1333
• Identity: 391/1333 - (29%)
• Similarity: 546/1333 - (40%)
• Gaps: 407/1333 - (30%)

  Fly   149 VKAKESVKMTSE--DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQ 211
            |...|::....|  |:|....:||:||||::||||||||||||..||:|||.||||||||:||||
Zfish     8 VHGDENMNGAGEQVDILPSNCLVKDRWKVLKKIGGGGFGEIYEAYDLLTRENVALKVESAQQPKQ 72

  Fly   212 VLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQ 276
            |||||||||||||||.|||:||||||||:||||||||||:|||:|||:||||.||:|||||||.|
Zfish    73 VLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFSMSTTLRLGKQ 137

  Fly   277 ILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGT 341
            ||::||:||||||||||||||||::||||..||:.||||||||||||...||||.||:.||||||
Zfish   138 ILESIEAIHSVGFLHRDIKPSNFAMGRLPSTCRKCYMLDFGLARQYTNTNGEVRPPRSVAGFRGT 202

  Fly   342 VRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSD 406
            |||||||||:|:||||||||||||||||||..|||||||||||||||..||:|:||:||||:|::
Zfish   203 VRYASINAHKNKEMGRHDDLWSLFYMLVEFTVGQLPWRKIKDKEQVGQIKERYEHRMLLKHMPAE 267

  Fly   407 LKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEK------------------VD 453
            ...|.:|:..|.|..:|||.:|:.:||..||.|.:.|::||||||                  ..
Zfish   268 FHIFYDHVLDLDYFTKPDYQLLMSVFENSMKDRVITENEPYDWEKSGTDTALPTSTHTPPQQNTR 332

  Fly   454 STA--IGNISATGNP-SIP-------IKSDYMH-----------GNITQMTVAASNASG---TEY 494
            .||  :|.::.|..| .:|       ::.:::.           ...|:...||.....   |::
Zfish   333 QTAAIVGVVNVTPVPGELPRENTDDVLQDEHLSDQENAPPALIPSRPTEPAPAAPAGEAWDETDF 397

  Fly   495 IRK--RAEIETAHITATDPLNIKEKVDKNCNATSLAQPAKGSGE-------PMVQHGNAANNQNI 550
            .|.  |..|....:.|.|.       |:.........||:| ||       |..:..|:..::.:
Zfish   398 NRNQLRISISKTQVAAEDG-------DEPAGGGRSVSPARG-GEGDAQARPPRYRRVNSPESERL 454

  Fly   551 T-----SKGLQQQSTLTNSQVAIANIQSA-PSMI-------------EREDVQYTKLEEGAPTKF 596
            :     ..|..::|.|........::.|: |:.:             .|.||.....:|.....|
Zfish   455 SGAEDRGDGADKRSRLDMLGSPSRHVYSSQPAQMLSLEGGQGERLAGGRHDVSADGDQEAHSNAF 519

  Fly   597 ITMKPNGECDNVDIAAKCIFEQKHVEANDDIVG-RASLSG-----------VEQHYKSQIKKHN- 648
            |...|..|.::.| :.:.:...|..|..|.:.| ..:.||           :|.|.:.:.:.|.
Zfish   520 IRSVPLAEEEDFD-SREWVMIDKETELKDFLPGAEPTTSGTTDEEPEELRPLEDHEERRRRVHGG 583

  Fly   649 -----------------------------------------------------------SPEIAN 654
                                                                       ||..:.
Zfish   584 AEAVVRPKTQRGMMIVAEEEGAGPSPGHSSCHTLPRSCPRRRESEPFGPDGPDIAVAEPSPSFSQ 648

  Fly   655 KQIQRTGTVT-----NDKTSEV-----------NRSTEEQKSTFGRLRVLTAPPMSVHD------ 697
            .:::|...|:     :|...||           .||:|  .|..|....|.||....||
Zfish   649 TRMKRVDFVSGVLMFDDLREEVVKTGGSGSDGSPRSSE--GSPEGAASTLLAPAHRDHDQEEGSR 711

  Fly   698 ----LPSGGGHSHQVSDLSGKQDPYAAT-----------------------------SNAAPIGI 729
                :.:|.|   |||...|:....|.|                             :.||.|..
Zfish   712 TLVLVSAGNG---QVSPGDGQGTLAALTPQGERPVPEESEPGTLSSVIKSEPRPIVMTTAAVITS 773

  Fly   730 NSSSTKFGSQHGQIFGLAAMPPINRRSATSTNLRPSS------------SASQRINSGSTIGGAV 782
            .|||..|.........:|....:|..:|..   |||.            ...:...||..:  .:
Zfish   774 GSSSPPFTKVERTFIHIAETSHLNVMTARH---RPSGFDEPISVERDEMGEEKEDRSGQLV--EI 833

  Fly   783 GNGSNTARSSVAGDHSVTQFALIDDEN-------VSALQQVTKGGALTLASQ-----------WK 829
            ...|...:....||....:.:..:.|.       :|:.::..   .:.||.|           .:
Zfish   834 ERNSKGIKVEREGDEKKKEESEAEKEKQEVENVIISSREEAE---TVFLAEQPVSIAIKENISIE 895

  Fly   830 SQFDDSEDTTDNEWNREHQLQPNL--------EQLIKLDISLPLNEA---KPFPQHGVAGTGKLI 883
            ::.||.:|....|..:|.:..|::        |...:.|:|.|..|:   ||.||.
Zfish   896 TKLDDEQDGVTTEKEQEQEESPSVSPEQNRDAEVEDEKDVSPPEVESPDRKPLPQR--------- 951

  Fly   884 NPPGEAKGRPKRYTLNITGIENYEALRISIPNCWSEPAMGNVLRKGLEPPAVQQAAFDDTVYRMD 948
                                      |..||...||...|:..........:|:..   ......
Zfish   952 --------------------------RSRIPVLMSEDETGSDKSSQTSQEQLQRTR---KSRHQQ 987

  Fly   949 IARNVCVRETYSEITHLARPSTSSVLRNRLPSPFKKDSALQLNSTNDSLD-KSRHRNSLPNVSVN 1012
            :||.|..|:.    ||:.|..::|.....|.:...:|.|.|.:.:....| |.:.|...|...:.
Zfish   988 LARLVLERKQ----THMMRSRSASSHSPTLSTTASEDEAHQSDDSAKGADGKIKSRIPRPVTPIR 1048

  Fly  1013 DIFDDL---------------QMKLNLDLGSAIQENNCCISGRLEIRV---IPKDTSHPDDSVYY 1059
            ..:|.|               |.:.|..:...||:     |..|...:   .||....|.
Zfish  1049 GSYDLLKCATLPQTQRSVSFIQYRTNSSINPKIQK-----SASLHTNIHQQPPKPQLRPS----- 1103

  Fly  1060 DAMGAVKNTP--TANEGHDHSDQAVNNCDEMEATSAVIAFPN--KSISKIMSPPGRDATEERTGA 1120
                  |..|  ..:.|..|:..:......:..|||    ||  :|||
Zfish  1104 ------KTLPPLPPSSGPSHTQGSRTATRTVTRTSA----PNATRSIS----------------- 1141

  Fly  1121 SLCSLYSAGVNKLKLNGNTAPRTQFKKGSTDGFGENESEFDFPLLNPSKIPVRQSKCASWA---- 1181
                              |:||:         :|.:.::      :||...:|:...|:..
Zfish  1142 ------------------TSPRS---------YGTSRTD------SPSPQRIRRQLAANETQRQA 1173

  Fly  1182 -----GADFISASKPLESAEVPQEIPYHPQSDT 1209
                 ....:|.|||.:|. .|::...||.:.|
Zfish  1174 QQPRPPVPSVSKSKPQDST-TPRKSKSHPSTST 1205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	200/260 (77%)
ttbk1b	XP_021328804.1	Protein Kinases, catalytic domain	33..294	CDD:473864	200/260 (77%)