DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bip2 and taf8

DIOPT Version :9

Sequence 1:	NP_651923.2	Gene:	bip2 / 43793	FlyBaseID:	FBgn0026262	Length:	1406	Species:	Drosophila melanogaster
Sequence 2:	XP_005162360.1	Gene:	taf8 / 393256	ZFINID:	ZDB-GENE-040426-1013	Length:	308	Species:	Danio rerio

Alignment Length:	329	Identity:	64/329 - (19%)
Similarity:	118/329 - (35%)	Gaps:	89/329 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VVVAQITQTIGYSCTLSAPLELLQDILQKFVQEFARDMHRHMEHANRIEPNLKDARLSIKNLSIN 77
            |||:.:....|:.....|.:|.|.:::|.::.|..|....:.||..|..|.|.|..:::..:..|
Zfish    41 VVVSALLTECGFDSAEKAVVETLTEMMQSYITEVGRCAKANCEHTARSTPTLSDVVITLVEMGFN 105

  Fly    78 VQELLDYIGNVEPVGF----IRDVPQFPIGKSVNMNFLKPGSAETLTRPVYIFEYLPPMQDPE-- 136
            |..|..|....:.:..    |.:.|..|  ||:.       :.:..|.|.:|..:.|...||.
Zfish   106 VDTLPVYAKRSQRMVITAPPITNAPVVP--KSLT-------AGQKRTHPAHIPSHFPDFPDPHTY 161

  Fly   137 -----LREIPADVQ----KEFSEKQE-------FCSKAEYSSTNAADKLGAKHIDSISPNTVINF 185
                 .||..:|.|    |..|::::       |.:|...:.:...|.:.|..:.:..|:.:
Zfish   162 IRTPTFREPVSDYQVVREKAASQRRDVERALTRFMAKTGETQSLFKDDISAFPLIAAKPSPI--- 223

  Fly   186 RSNAFELDVGSSVREMSSVVMTTGGFISPAIEGKLPEDIIPDIVEKFLGLDAPFSPTIIVNSLQK 250
                                        |.:...||.::....:|:             .:|.::
Zfish   224 ----------------------------PYLSALLPSELELQSLEE-------------TDSSEQ 247

  Fly   251 SPQLALSDRDKTVNPRKIIPSETKIFKQNAALLTSG------HSESSIIYASNNHTMLTVTTPKK 309
            ..|:   |.|.  |...|:..::...|:|..|...|      .:|.::|   :|..:..|..||.
Zfish   248 DDQM---DNDN--NTSHIMQDDSGADKENEVLPPGGVVPSGKANEENMI---DNPYLRPVKKPKV 304

  Fly   310 NRKQ 313
            .||:
Zfish   305 RRKK 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bip2	NP_651923.2	BTP	4..80	CDD:128846	18/66 (27%)
bip2	NP_651923.2	PHD_TAF3	1342..1387	CDD:276997
taf8	XP_005162360.1	Bromo_TP	32..108	CDD:284856	18/66 (27%)
taf8	XP_005162360.1	TAF8	146..199	CDD:176263	11/52 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2389
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1475
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840