Protein Alignment Taf3 and Taf3

DIOPT Version :10

• Sequence 1: NP_651923.2
• Gene: Taf3 / 43793
• FlyBaseID: FBgn0026262
• Length: 1406
• Species: Drosophila melanogaster
• Sequence 2: NP_001258271.1
• Gene: Taf3 / 100360100
• RGDID: 2324594
• Length: 930
• Species: Rattus norvegicus
• Alignment Length: 1460
• Identity: 313/1460 - (21%)
• Similarity: 469/1460 - (32%)
• Gaps: 587/1460 - (40%)

  Fly     2 MADRYASDLALVVVAQITQTIGYSCTLSAPLELLQDILQKFVQEFARDMHRHMEHANRIEPNLKD 66
            |.:.|:..|..|.||||.|.:|:.....:...||.|:||:::|:..|..||:.|...|.:|.|.|
  Rat     1 MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDD 65

  Fly    67 ARLSIKNLSINVQELLDYIGNVEPVGFIRDVPQFPIGKSVNMNFLKPGSAETLTRPVYIFEYLPP 131
            ...:.:.:.:|:.||.|||.|:|||.|...:|.||:.|:..:.|.:|||.:...|..||.:||||
  Rat    66 VGEAFQLMGVNLHELEDYIHNIEPVTFPHQIPSFPVSKNSVLQFPQPGSKDAEERKDYIPDYLPP 130

  Fly   132 MQDPELREIPADVQKEFSEKQEFCSKAEYSSTNAADKLGAKHIDSISPNTVINFRSNAFELDVGS 196
            :         ...|:|..|:|
  Rat   131 I---------VSSQEEEEEEQ-------------------------------------------- 142

  Fly   197 SVREMSSVVMTTGGFISPAIEGKLPED-------IIPDIVEKFLGLDAPFSPTIIVNSLQKSPQL 254
                    |.|.||..:.|::..|.||       :|.|  |.|||.....||.:......|.|:|
  Rat   143 --------VPTDGGTSAEAMQVPLEEDDELEEEEVIND--ENFLGKRPLDSPEVEEMPSMKRPRL 197

  Fly   255 ALSDRD-------------KTVNPRKIIPSETKIFKQNAALLTSGHSESSIIYASNNHTMLTVTT 306
            ..|..|             .::||:||.|           :|:..|.:.|        |.|...:
  Rat   198 LNSKGDSLDVVLLEAREPLSSINPQKIPP-----------MLSPVHVQDS--------TDLAPPS 243

  Fly   307 PKKNRKQKHDLICEPGQSELLTNPFEKAQEKSQRKALKMYKQTSKNQRDSSINQIQNMKKLKKKF 371
            |            ||.    :..||.|:|.
  Rat   244 P------------EPP----MLAPFAKSQL----------------------------------- 257

  Fly   372 NRGSFDPNKKHLE-KIFKKQSKLKQNDLQLDIDEKHFLQNSQTTSGLAIKANSNENALQADIPSQ 435
                  |..|.|| |.|..::|.|                   .|....|..|.:.||      .
  Rat   258 ------PIAKPLETKPFTPKTKTK-------------------ASSPGQKTKSPKAAL------S 291

  Fly   436 PPTVTSQIENNFRNSIYPVQPSVIQQTQVLLAEKKSGSEPERSKLDIFKKISKPRTPRPDIGATL 500
            |..:.|.|.:          |..|.:      ||||   |.|||        .|::|:.....|.
  Rat   292 PARLGSPIRS----------PKTIPK------EKKS---PGRSK--------SPKSPKSPKIVTH 329

  Fly   501 VP-----PGTGVSVFGSTMTPSALI-------SLPSGTTITPTPSLGLNSENKNVPSMKINPCNI 553
            ||     |.|      ...||||::       ::|...|.|| |..|
  Rat   330 VPQPPVRPET------PNRTPSAMVVEKTVKETIPVKPTQTP-PETG------------------ 369

  Fly   554 FDGTIPLTKAGVEMSIIDSPKPKKRGRKPGGKNVIKQTNVVSQPLINKVERKKSSQAITLPLSSS 618
                    |..:||.:       |:|             ||:...|:               .|.
  Rat   370 --------KLNIEMQL-------KKG-------------VVTDKTID---------------DSI 391

  Fly   619 PMIITQSSLNVSPPTEPLNLCN-TEQPSNNFLSNLYAKEKKDRKKYKSLPENVMQLDKSCSPEKA 682
            ..:|.::.....|  :|....: :|...:.|.|                |:.:..  ..|:..||
  Rat   392 DAVIARACAEREP--DPFEFSSGSESEGDTFTS----------------PKRISV--SECTTPKA 436

  Fly   683 STLHNSI-----RPTKQNNDVQCSDKFVT----ISNALSNASIYPGIQTGMVPLLPLLQFPPRPG 738
            ||..|:.     .|...:.....||...|    |...:..|.:  |..:.|.|..|.:.
  Rat   437 STSSNNFTKSLATPLPLSGGTSSSDNSWTMDASIDEVVRKAKL--GAPSNMPPTFPYIS------ 493

  Fly   739 LIPTGPGLFPAVTGLVGFGNHGNRIPISPFIDYPGPE---ESVADTVRCPP---IKDSPVTDSDQ 797
                                       ||.|..|.||   :...:..:.||   :|.....:...
  Rat   494 ---------------------------SPSISPPTPEPLHKGYEEKAKPPPSVDVKKKLKKELKT 531

  Fly   798 FLSRSSTQTDLQMDRNYCNVAPLVPDSMKFAECKSVSCASTILENPSAQATSKINTKPLLEASGN 862
            .|.:...|.|.:.:|..........|.::..|           :...|....|...|.|::  ..
  Rat   532 KLKKKEKQRDRERERERNKEKSKEKDKVRERE-----------KEKEAGKEVKYPWKELMK--DE 583

  Fly   863 PDDP----IEVSDDSDESMHNRQMVQRKTPISSPTYVKTSFAELNPSSFTSAASNGEEKSKMDLR 923
            ..||    |:..:|.|..:..:..:.|:.            .|.:............||.|.:
  Rat   584 ESDPYKFKIKEFEDIDAKVRLKDGIVRRE------------REKHKDKKKDRERGKREKDKRE-- 634

  Fly   924 NIVSLSSNEPLKKFKKLVKQSFPDVKSVPHTPASHSSFPQFNLPNFMGGDKFSLAGGADLIPLSR 988
                   .|.||:..:..|...|..:.|  .|....:.|.|             :..|..:|
  Rat   635 -------RERLKEKSREDKIKAPPTQLV--LPPKEMALPLF-------------SPAAVRVP--- 674

  Fly   989 VSDSEYSSKIVPFSSLGGTIPNQIKISEEHNIFSTFSNYEDITITPTGLTSLEPKMRKHHKKLKK 1053
                   :.:..||.:   :|.::                           .|.|.:...|:.||
  Rat   675 -------AMLPAFSPM---LPEKL---------------------------FEEKEKPKEKERKK 702

  Fly  1054 VKEGKNKKKKEKKDKSKKADQIGLPSFKSDRKIKANDKRQKKEKKKDKDKQILVHIPDDTEEFDK 1118
            .|:.|.|||:::|:|.||            .|.|..:||::::::|:|::          .:.:|
  Rat   703 DKKEKKKKKEKEKEKEKK------------EKEKEKEKREREKREKEKER----------HKHEK 745

  Fly  1119 VPLANNDEPVLKSSSMTINPSLGAATSGISPNQIPKLTLKLSGKSTLFSSSEKEMTDAGKLKQTT 1183
            :.:    |||:.:.|..                ||:|||::.               ||:.|  .
  Rat   746 IKV----EPVIPAPSPV----------------IPRLTLRVG---------------AGQDK--I 773

  Fly  1184 ILSSENKKRERDNSPELARFSPLVTGPPKNKQSETLHLGNSSTAVLPVPSPVAVRAVQLPVSQTS 1248
            ::|......|...:|.|.|..   |.||                 .|||.||.|....||
  Rat   774 VISKVVPAPEAKPAPSLNRPK---TPPP-----------------APVPIPVRVSPTPLP----- 813

  Fly  1249 SNSAGWLSNPNNSNTASSTLSASSVLLPQQLMLAPHTIMNNFVPAMCNSTGTVSKSGLCSSPPNT 1313
                             ..|.|.:.:.| .||.:|       .||:       |.:|...:|
  Rat   814 -----------------PPLLAQAAVCP-ALMPSP-------APAL-------SAAGSAKAP--- 843

  Fly  1314 SEENANAMQIAESSRPSSYV--DAEGNRIWICPACGKVDDGSAMIGCDGCDAWYHWICVGITFAP 1376
                   ::...:...|:||  |..||:|||||.|.|.||||.|||||.||.||||.||||..||
  Rat   844 -------VRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMAAP 901

  Fly  1377 KDNDDWFCRVCVTKKRIHGSEKKKRRNKKK 1406
            .:...|||..|..|.:   .:||.:|.|.:
  Rat   902 PEEMQWFCPKCANKIK---KDKKHKRRKHR 928

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Taf3	NP_651923.2	HFD_TAF3	4..95	CDD:467041	34/90 (38%)
		TNG2	<1289..1387	CDD:227367	42/99 (42%)
		PHD_TAF3	1342..1387	CDD:276997	29/44 (66%)
Taf3	NP_001258271.1	HFD_TAF3	3..94	CDD:467041	34/90 (38%)
		Herpes_BLLF1	<235..>463	CDD:282904	42/241 (17%)
		PTZ00121	<556..>662	CDD:173412	15/106 (14%)
		PHD_TAF3	867..912	CDD:276997	4/44 (9%)