Protein Alignment CaMKI and Pnck

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_036170.1
• Gene: Pnck / 93843
• MGIID: 1347357
• Length: 343
• Species: Mus musculus
• Alignment Length: 327
• Identity: 195/327 - (59%)
• Similarity: 248/327 - (75%)
• Gaps: 19/327 - (5%)

  Fly    21 LNKQV-SIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHF-AVKIIDKKALKGKEESLENEIRVLR 83
            |.||. .|...|.:...||:||||||.||:.:.|  .|. |:|.|.||||:|||..:||||.|||
Mouse     4 LKKQTEDISSVYEIREKLGSGAFSEVMLAQERGS--AHLVALKCIPKKALRGKEALVENEIAVLR 66

  Fly    84 RFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHL 148
            |.|               |||||.|.:.:|..|.:||.|||||||||||||:|:|||||||||||
Mouse    67 RIS---------------HPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHL 116

  Fly   149 IRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMATACGTPGYVAP 213
            :.|:|.||.|:|..|:||||||||||||.:|.:|||||:|||||||::...::.|||||||||||
Mouse   117 VGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAP 181

  Fly   214 EVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHF 278
            |:|.|||||||||||::|||||||||||||||||:|..||:|||:..:|||||:||:||||||.|
Mouse   182 ELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDF 246

  Fly   279 IKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIRQMQ 343
            |::|:....:||:||:|||.|.||||:.|..|:|.|:||||::||||::.||:|:.|.:.:|.::
Mouse   247 IRHLLERDPQKRFTCQQALQHLWISGDAAFDRDILGSVSEQIQKNFARTHWKRAFNATSFLRHIR 311

  Fly   344 RM 345
            ::
Mouse   312 KL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	171/274 (62%)
Pnck	NP_036170.1	STKc_CaMKI_beta	11..287	CDD:271071	181/292 (62%)
		Calmodulin-binding. /evidence=ECO:0000250	290..311		9/20 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	314..343		195/327 (60%)