Protein Alignment CaMKI and camk1b

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: XP_021335371.1
• Gene: camk1b / 794026
• ZFINID: ZDB-GENE-141014-1
• Length: 394
• Species: Danio rerio
• Alignment Length: 374
• Identity: 220/374 - (58%)
• Similarity: 268/374 - (71%)
• Gaps: 35/374 - (9%)

  Fly     1 MPLFGKKDSGKKAKAKDLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDK 65
            |||.....|.||          |..:|::.|:...:|||||||||.|||.|.: .:..|||.|.|
Zfish    13 MPLGEDGPSWKK----------KTANIKDIYDFKEVLGTGAFSEVMLAEEKRT-RKLVAVKCIAK 66

  Fly    66 KALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGEL 130
            |||:|||.|:||||.||.               ::.|.|||.|.:.:|.||.:||||:||:||||
Zfish    67 KALEGKENSIENEIAVLH---------------KIKHANIVSLEDIFESKSHLYLVMQLVSGGEL 116

  Fly   131 FDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKM 195
            ||||||||.|||||||.||:|||:||.|:|:.|:||||||||||||||.|::||||||||||||:
Zfish   117 FDRIVEKGFYTEKDASKLIQQILDAVKYLHDMGIVHRDLKPENLLYYSMDEESKIMISDFGLSKI 181

  Fly   196 EDSG-IMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKG 259
            |.|| :|:|||||||||||||||||||.||||.||||||:||||||||||||||||.||.|||:.
Zfish   182 EGSGSVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILRA 246

  Fly   260 DFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNF 324
            ::||||||||:||:|||.||.:||.....:||||:|||.|.||:|:.|..:|||.:||.|:||||
Zfish   247 EYEFDSPYWDDISDSAKDFIVHLMEKDPNQRYTCEQALQHPWIAGDTALDKNIHESVSAQIKKNF 311

  Fly   325 AKSRWKQAYYAATVIRQMQRMALNSNSNANFDSSNSSNQDSTTPTAATG 373
            |||:||||:.|..|:|.|:|:.|.        :|......:|.|:...|
Zfish   312 AKSKWKQAFNATAVVRHMRRLQLG--------TSQEGPPQNTLPSPCHG 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	182/274 (66%)
camk1b	XP_021335371.1	Protein Kinases, catalytic domain	29..291	CDD:473864	184/277 (66%)