Protein Alignment CaMKI and Phkg2

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_081164.2
• Gene: Phkg2 / 68961
• MGIID: 1916211
• Length: 406
• Species: Mus musculus
• Alignment Length: 294
• Identity: 110/294 - (37%)
• Similarity: 165/294 - (56%)
• Gaps: 32/294 - (10%)

  Fly    29 EKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLE-------NEIRVLRRFS 86
            :||:...::|.|..|.||....: :.|:.|||||::..|.:...|.||       .|:.:||:.:
Mouse    22 QKYDPKDIIGRGVSSVVRRCVHR-ATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVA 85

  Fly    87 ANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQ 151
            .              ||:|:.|:::||..|.::||.:|:..|||||.:.||.:.:||:...::|.
Mouse    86 G--------------HPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRS 136

  Fly   152 ILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLS-KMEDSGIMATACGTPGYVAPEV 215
            :||||.::|...:|||||||||:|.   ||:.:|.:||||.| .:|....:...||||||:|||:
Mouse   137 LLEAVSFLHANNIVHRDLKPENILL---DDNMQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEI 198

  Fly   216 L------AQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISES 274
            |      ....|||.||:|:.|||.:.||.|.|||:......:...|::|.::|.||.||:.|.:
Mouse   199 LKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDRSNT 263

  Fly   275 AKHFIKNLMCVTVEKRYTCKQALGHAWISGNEAS 308
            .|..|..|:.|..|.|.|.:|||.|.:....|.|
Mouse   264 VKDLISKLLQVDPEARLTAEQALQHPFFERCEGS 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	108/285 (38%)
Phkg2	NP_081164.2	Protein Kinases, catalytic domain	13..291	CDD:473864	108/286 (38%)
		Calmodulin-binding (domain-N). /evidence=ECO:0000250	306..330
		Calmodulin-binding (domain-C). /evidence=ECO:0000250	346..370