Protein Alignment CaMKI and Camk1

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: XP_038962912.1
• Gene: Camk1 / 171503
• RGDID: 629473
• Length: 414
• Species: Rattus norvegicus
• Alignment Length: 371
• Identity: 217/371 - (58%)
• Similarity: 274/371 - (73%)
• Gaps: 30/371 - (8%)

  Fly     1 MPLFGKKDSGKKAKAKDLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDK 65
            ||  |..:..:..:|:|::::         |:...:|||||||||.|||.|.:. :..|:|.|.|
  Rat    32 MP--GAVEGPRWKQAEDIRDI---------YDFRDVLGTGAFSEVILAEDKRTQ-KLVAIKCIAK 84

  Fly    66 KALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGEL 130
            |||:|||.|:||||.||.               ::.|||||.|.:.||....:||:|:||:||||
  Rat    85 KALEGKEGSMENEIAVLH---------------KIKHPNIVALDDIYESGGHLYLIMQLVSGGEL 134

  Fly   131 FDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKM 195
            ||||||||.|||:|||.||.|:|:||.|:|:.|:||||||||||||||.|:||||||||||||||
  Rat   135 FDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKM 199

  Fly   196 EDSG-IMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKG 259
            ||.| :::|||||||||||||||||||.||||.||||||:||||||||||||||||.||.||||.
  Rat   200 EDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKA 264

  Fly   260 DFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNF 324
            ::||||||||:||:|||.||::||....|||:||:|||.|.||:|:.|..:|||.:||||:||||
  Rat   265 EYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNF 329

  Fly   325 AKSRWKQAYYAATVIRQMQRMALNSNSNANFDSSNSSNQDSTTPTA 370
            |||:||||:.|..|:|.|:::.|.::...  ....:|:.:..||||
  Rat   330 AKSKWKQAFNATAVVRHMRKLQLGTSQEG--QGQTASHGELLTPTA 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	180/274 (66%)
Camk1	XP_038962912.1	STKc_CaMKI_alpha	47..309	CDD:271069	182/286 (64%)