DRSC/TRiP Functional Genomics Resources

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Protein Alignment CaMKI and Camk1g

DIOPT Version :10

Sequence 1:NP_524622.1 Gene:CaMKI / 43792 FlyBaseID:FBgn0016126 Length:405 Species:Drosophila melanogaster
Sequence 2:NP_878262.1 Gene:Camk1g / 171358 RGDID:621800 Length:476 Species:Rattus norvegicus


Alignment Length:343 Identity:190/343 - (55%)
Similarity:256/343 - (74%) Gaps:19/343 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 GKKAKAKDLKELNKQ-VSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEE 73
            |:| :.:|.....|| .:|.:.:....:||:||||||.|.:.:.: |:.||:|.| ||:...::.
  Rat     2 GRK-EEEDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVT-GKLFALKCI-KKSPAFRDS 63

  Fly    74 SLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKG 138
            ||||||.||:               |:.|.|||.|.:.||..:..||||:||:||||||||:|:|
  Rat    64 SLENEIAVLK---------------RIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERG 113

  Fly   139 SYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMAT 203
            .|||||||.:|:|:|.||.|:||.|:||||||||||||.:|:::|||||:||||||||.:|:|:|
  Rat   114 VYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGVMST 178

  Fly   204 ACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYW 268
            ||||||||||||||||||.||||.||||||:|||||||||||:|.::.||.:|.:|.:||:||:|
  Rat   179 ACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFW 243

  Fly   269 DEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQAY 333
            |:||||||.||.:|:.....:||||::||.|.||.||.|..|:|:.:||.|::||||||:|:||:
  Rat   244 DDISESAKDFICHLLEKDPNERYTCEKALRHPWIDGNTALHRDIYPSVSLQIQKNFAKSKWRQAF 308

  Fly   334 YAATVIRQMQRMALNSNS 351
            .||.|:..|:::.:|.:|
  Rat   309 NAAAVVHHMRKLHMNLHS 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CaMKINP_524622.1 STKc_CaMKI 27..301 CDD:270985 160/273 (59%)
Camk1gNP_878262.1 STKc_CaMKI_gamma 19..303 CDD:271068 175/300 (58%)
Autoinhibitory domain 277..317 21/39 (54%)
Calmodulin-binding 297..318 12/20 (60%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 326..387 1/1 (100%)

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