Protein Alignment CaMKI and Camk4

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: XP_006525606.1
• Gene: Camk4 / 12326
• MGIID: 88258
• Length: 497
• Species: Mus musculus
• Alignment Length: 383
• Identity: 155/383 - (40%)
• Similarity: 225/383 - (58%)
• Gaps: 49/383 - (12%)

  Fly    31 YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKI----IDKKALKGKEESLENEIRVLRRFSANHFD 91
            :.:...||.||.|.|...:.|.:. :.:|:|:    :|||.::       .||.||
Mouse    70 FEVESELGRGATSIVYRCKQKGTQ-KPYALKVLKKTVDKKIVR-------TEIGVL--------- 117

  Fly    92 GKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEAV 156
                  .||:||||::|.|.:|..:::.||:||||||||||||||||.|:|:||:..::||||||
Mouse   118 ------LRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAV 176

  Fly   157 DYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSK-MEDSGIMATACGTPGYVAPEVLAQKP 220
            .|:||.|:||||||||||||.:|..|:.:.|:|||||| :|...:|.|.||||||.|||:|....
Mouse   177 AYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCA 241

  Fly   221 YGKAVDVWSIGVISYILLCGYPPFYDE-NDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMC 284
            ||..||:||:|:|:||||||:.||||| .|..:|.:||..::.|.||:|||:|.:||..:|.|:.
Mouse   242 YGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIV 306

  Fly   285 VTVEKRYTCKQALGHAWISGNEASSRNIH-GTVSEQLKKNFAKSRWKQAYYAATVIRQMQRMALN 348
            :..:||.|..|||.|.|::|..|:.  :| .|..::|::..|:.:.|.|..|...   ..|:...
Mouse   307 LDPKKRLTTFQALQHPWVTGKAANF--VHMDTAQKKLQEFNARRKLKAAVKAVVA---SSRLGSA 366

  Fly   349 SNSNANFDSSNSSNQDSTTPTAATGAWTSNVL-----------SSQQSVQSHAQEMNK 395
            |:|:.:...::.::.|   |.:...|..|..|           ..|...::.|.||.|
Mouse   367 SSSHTSIQENHKASSD---PPSTQDAKDSTDLLGKKMQEEDQEEDQVEAEASADEMRK 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	132/275 (48%)
Camk4	XP_006525606.1	STKc_CaMKIV	66..359	CDD:270987	142/313 (45%)