Protein Alignment CaMKI and camk2a

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: XP_012813848.1
• Gene: camk2a / 100101771
• XenbaseID: XB-GENE-868353
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 373
• Identity: 145/373 - (38%)
• Similarity: 199/373 - (53%)
• Gaps: 39/373 - (10%)

  Fly    29 EKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKE-ESLENEIRVLRRFSANHFDG 92
            |:|.|...||.||||.||.. .|...|:.:|.|||:.|.|..:: :.||.|.|:.|
 Frog    11 EEYQLFEELGKGAFSIVRRC-VKVLSGQEYAAKIINTKKLSARDHQKLEREARICR--------- 65

  Fly    93 KCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVD 157
                  .|.|||||:|.::..::...|||.:||||||||:.||.:..|:|.||||.|:||||||.
 Frog    66 ------LLKHPNIVRLHDSISEEGHHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVL 124

  Fly   158 YMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMAT---ACGTPGYVAPEVLAQK 219
            :.|:.|||||||||||||..|....:.:.::||||: :|..|....   ..|||||::||||.:.
 Frog   125 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA-IEVEGEQQAWFGFAGTPGYLSPEVLRKD 188

  Fly   220 PYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMC 284
            |||||||:|:.|||.||||.|||||:||:...|:.||..|.::|.||.||.::..||..|..::.
 Frog   189 PYGKAVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 253

  Fly   285 VTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIRQMQRMALNS 349
            :...||.|..:||.|.|||.....:..:|...:....|.|...|..:.....|::.........|
 Frog   254 INPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKS 318

  Fly   350 NSNANFD------------------SSNSSNQDSTTPTAATGAWTSNV 379
            .||...|                  |:|::.:|..|...:..|...|:
 Frog   319 GSNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKDFSLAAQNENI 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	127/275 (46%)
camk2a	XP_012813848.1	STKc_CaMKII	11..302	CDD:270988	134/307 (44%)
		CaMKII_AD	384..511	CDD:285524